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Behavioural Intervention

Home-Based Exercise for Primary Progressive Aphasia (HEPPA Trial)

N/A
Waitlist Available
Led By Louis Bherer
Research Sponsored by Montreal Heart Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
A clinical diagnosis of Primary Progressive Aphasia
Must not have
Any severe respiratory disease (e.g., asthma, COPD, COVID-19)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months post-intervention
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing a new exercise program that can be done at home by adults with Primary Progressive Aphasia. The goal is to see if the program is practical and effective.

Who is the study for?
This trial is for adults with Primary Progressive Aphasia, a type of language disorder. Participants should be clinically diagnosed and able to perform basic exercises at home.
What is being tested?
The study tests a new exercise program done at home designed for people with language disorders like Primary Progressive Aphasia. It's a pilot study, meaning it's an early test to see if the idea is feasible.
What are the potential side effects?
Since this is an exercise-based intervention, potential side effects may include muscle soreness, fatigue, or injury from physical activity. Specific risks will depend on individual health conditions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I have been diagnosed with Primary Progressive Aphasia.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I do not have severe respiratory issues like asthma, COPD, or COVID-19.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months post-intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months post-intervention for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Evaluate the compliance rate of a 6-month exercise intervention in individuals with Primary Progressive Aphasia
Evaluate the program completion rate of a 6-month exercise intervention in individuals with Primary Progressive Aphasia
Evaluate the recruitment rate of a 6-month exercise intervention in individuals with Primary Progressive Aphasia
+2 more
Secondary study objectives
Document change in balance performance
Document change in lower limb muscle strength
Document change in upper limb muscle strength
+17 more
Other study objectives
Document Cognitive Reserve
Document changes in anxiety
Document changes in depressive symptomatology
+7 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Home-based multicomponent exercise intervention programExperimental Treatment1 Intervention

Find a Location

Who is running the clinical trial?

Montreal Heart InstituteLead Sponsor
123 Previous Clinical Trials
80,747 Total Patients Enrolled
Louis BhererPrincipal InvestigatorCentre ÉPIC, Institut de cardiologie de Montréal
~5 spots leftby Nov 2025
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