← Back to Search

SECM Capsule Imaging for Eosinophilic Esophagitis

N/A

Waitlist Available

Led By Guillermo Tearney, MD, PhD

Research Sponsored by Massachusetts General Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

12 years of age or older undergoing endoscopic biopsy for evaluation of EoE

Must not have

Esophageal fistula and/or esophageal strictures with a stricture diameter that is smaller than the diameter of the capsule

Inability to swallow pills and capsules

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 10 minutes (roughly the amount of time it takes to image the esophagus via secm capsule)

Awards & highlights

No Placebo-Only Group

Summary

This trial is comparing a new, non-invasive way of diagnosing a condition called eosinophilic esophagitis to the current standard of care, which involves taking a tissue sample through a scope.

Who is the study for?

This trial is for individuals aged 12 or older who are undergoing an endoscopic biopsy to evaluate Eosinophilic Esophagitis. Participants must be able to swallow pills and capsules, and cannot have esophageal strictures narrower than the capsule or esophageal fistula.

What is being tested?

The study is testing a new imaging technique called SECM Tethered Capsule Endoscopy (TCE) against the standard biopsy method for diagnosing Eosinophilic Esophagitis in the esophagus.

What are the potential side effects?

Potential side effects may include discomfort from swallowing the SECM capsule, risk of gagging, and possible irritation of the esophagus. However, specific side effects will depend on individual reactions to the capsule.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 12 or older and getting a biopsy to check for EoE.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I have a narrow or blocked esophagus smaller than a capsule.

Select...

I cannot swallow pills or capsules.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 10 minutes (roughly the amount of time it takes to image the esophagus via secm capsule)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~10 minutes (roughly the amount of time it takes to image the esophagus via secm capsule)

This trial's timeline: 3 weeks for screening, Varies for treatment, and 10 minutes (roughly the amount of time it takes to image the esophagus via secm capsule) for reporting.