Behavioral Nudges for Medication Adherence in Cardiovascular Disease

Recruiting in Palo Alto (17 mi)

+4 other locations

Overseen byMichael Ho, MD, PhD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University of Colorado, Denver

No Placebo Group

Trial Summary

What is the purpose of this trial?This trial aims to see if sending text message reminders and encouragements can help patients with cardiovascular conditions take their medication more regularly. The study focuses on patients who often forget or have trouble keeping up with their medication. By using simple text messages, the researchers hope to improve medication adherence and overall health outcomes.

Eligibility Criteria

This trial is for patients in Colorado with conditions like atrial fibrillation, coronary artery disease, diabetes, high cholesterol, or high blood pressure. They must be taking specific medications for these conditions and have a phone and mailing address listed in their electronic health records.

Inclusion Criteria

I have diabetes and am on medication for it.

I have heart disease and am taking specific heart medications.

I have high blood pressure and am on medication like Beta-blockers or ACE inhibitors.

+2 more

Exclusion Criteria

Patients with a mailing address outside of the state of Colorado

I do not speak English or Spanish.

You are pregnant at the time of the data collection.

+2 more

Participant Groups

The study is testing whether personalized text message reminders can help people with chronic cardiovascular diseases take their medication regularly. It aims to see if this 'nudge' approach improves adherence to prescribed drug regimens.

4Treatment groups

Experimental Treatment

Active Control

Group I: Optimized nudge plus AI Chat BotExperimental Treatment1 Intervention

An optimized nudge text will be delivered to patients to remind them to refill their medications at days 1 and 3 after they have been labeled as non-adherent. If the patient has not filled their medication on days 5 and 7, in addition to receiving an optimized nudge text, an AI will conduct interactive chat via a chat bot to assess barriers filling the medication as described in Aim 1 above. If they still have not filled the medication, they will receive another message on day 10.

Group II: Optimized nudgeExperimental Treatment1 Intervention

An optimized nudge text will be delivered to patients to remind them to refill their medications at days 1, 3, 5, 7 and 10 after they have been labeled as non-adherent.

Group III: Generic NudgeExperimental Treatment1 Intervention

A generic reminder text will be delivered to patients to refill their medication at days 1, 3, 5, 7 and 10 after they been labeled as non-adherent.

Group IV: Usual CareActive Control1 Intervention

This group will not receive an intervention. We have included a usual care group to demonstrate the impact of the text messaging interventions above and beyond usual care given that many prior medication adherence interventions have demonstrated small to negligible effects.