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Cognitive Behavioral Therapy

Cognitive Behavioural Therapy for Postpartum Depression

N/A

Waitlist Available

Led By Ryan Van Lieshout, MD, PHD

Research Sponsored by McMaster University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Infants must be between 4-12 months old at enrollment

Meets diagnostic criteria for comorbid psychiatric conditions

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

No Placebo-Only Group

Summary

This trial will study whether online group CBT for maternal postpartum depression leads to greater improvements in infant emotion regulation than treatment as usual.

Who is the study for?

This trial is for English-speaking women over 18 living in Ontario with postpartum depression, as indicated by an EPDS score of at least 10. Their infants should be aged between 4-8 months. Women with bipolar disorder, current psychotic disorders, substance abuse issues, or certain personality disorders cannot participate.

What is being tested?

The study tests if adding online group cognitive behavioral therapy (CBT) to the usual treatment helps improve how babies manage their emotions better than just the usual treatment alone. The effects will be checked right after and six months post-treatment.

What are the potential side effects?

Since this trial involves psychological therapy rather than medication, typical side effects associated with drugs are not expected. However, participants may experience emotional discomfort discussing personal topics during CBT sessions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My infant is between 4 to 12 months old.

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I have been diagnosed with a mental health condition.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Infant Temperament

Infant emotion regulation

Maternal Anxiety

+1 more

Secondary study objectives

Brain-to-brain Synchrony (fNIRS)

Epigenetic Analyses

Parent-Child Early Relational Assessment (PCERA)

+1 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Treatment (9-week online CBT group)Experimental Treatment1 Intervention

Participants assigned to the treatment group will continue to receive any healthcare they might already be receiving (e.g. family doctor, midwife, Obstetrician/Gynecologist, etc.) and participate in a 9-week group Cognitive Behavioral Therapy (CBT) intervention for Postpartum Depression (PPD) delivered via Zoom by two trained psychologists, social workers, nurses, and/or psychiatrists.

Group II: Control (treatment as usual)Active Control1 Intervention

The control group will receive standard postnatal care from their obstetrician, midwife, and/or family physician

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Group Cognitive Behavioural Therapy (CBT)

2020

N/A

~160

0 / 2Eligibility criteria met