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Behavioral Intervention

Neurobehavioral Therapy for Epilepsy and Depression

N/A
Waitlist Available
Led By Melissa Fadipe, MSN, APRN, FNP-C
Research Sponsored by The University of Texas Health Science Center, Houston
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
English speaking veterans
Has an active clinical diagnosis of major depressive disorder based on the International Classification of Diseases, 10th version (ICD-10)
Must not have
Have an ICD-10 diagnosis of psychogenic non-epileptic seizures or conversion disorder.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, end of session 12(12 weeks form baseline)
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to test if an online group therapy with text messaging can help Veterans with epilepsy and major depressive disorder.

Who is the study for?
This trial is for veterans who have both epilepsy and major depressive disorder. It's designed to see if they can benefit from an online group therapy program that also uses text messaging.
What is being tested?
The study is testing the effectiveness of Neurobehavioral Therapy (NBT) delivered through an online platform with supplementary text messages, specifically aimed at helping veterans manage epilepsy and depression.
What are the potential side effects?
Since this trial involves therapy rather than medication, side effects are minimal but may include discomfort discussing personal issues or potential stress from participation in group discussions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am a veteran and I speak English.
Select...
I have been diagnosed with major depression.
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I have been diagnosed with epilepsy and had at least one seizure in the last five years.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I have been diagnosed with seizures not caused by epilepsy.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, end of session 12(12 weeks form baseline)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, end of session 12(12 weeks form baseline) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Enrollment rate
Retention rate
User satisfaction as assessed by The Participant Satisfaction Survey
Secondary study objectives
Change in depression as assessed by the Patient Health Questionnaire-9 (PHQ-9)
Change in efficacy in the self management of epilepsy as assessed by the Epilepsy Self-Efficacy Scale (ESES)
Change in quality of Life as assessed by the Quality of Life in Epilepsy Inventory-10 (QOLIE-10)
+1 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Neurobehavioral therapyExperimental Treatment1 Intervention

Find a Location

Who is running the clinical trial?

The University of Texas Health Science Center, HoustonLead Sponsor
957 Previous Clinical Trials
348,040 Total Patients Enrolled
8 Trials studying Epilepsy
493 Patients Enrolled for Epilepsy
Melissa Fadipe, MSN, APRN, FNP-CPrincipal InvestigatorThe University of Texas Health Science Center, Houston
~8 spots leftby Feb 2025