Non-invasive Brain Stimulation
Theta-burst Stimulation for Memory Improvement in Mild Cognitive Impairment
This trial is testing whether transcranial magnetic stimulation can help improve memory for people with mild cognitive impairment. The study will enroll people with MCI who will be randomly assigned to receive active or sham brain stimulation, where they won't know if they're receiving the real treatment or not.
Behavioral Intervention
High-Intensity Exercise for Cognitive Impairment with HIV
This trial will study if exercise can help people 50+ living with HIV who have suboptimal cognition. 60 participants in Alabama will be monitored over 3 months to measure the effects of exercise.
Neuromodulation
Cognitive Walking + Brain Stimulation for Older Adults
This trial aims to test if using a combination of cognitive walking exercises and electrical brain stimulation can help older adults improve their cognitive and walking functions. The study will compare the effects of real brain stimulation with fake
Behavioural Intervention
Combination Therapies + Lifestyle Modifications for Traumatic Brain Injury
This trial tests if combining talking therapy, brain exercises, and lifestyle changes can help people with neurocognitive disorders live better lives by improving their thinking, brain function, and daily habits.
Popular Filters
Trials for Dementia Patients
Behavioural Intervention
Cognitive Rehabilitation for Stroke-Related Cognitive Impairment
This trial will compare two approaches to cognitive rehabilitation in adults with stroke and persistent mild to moderate cognitive impairment. One approach will add in-lab training on everyday activities and procedures to transfer improvements to daily life; the other approach will add in-lab training on relaxation, healthy nutrition, and healthy sleep with procedures to promote integration of lifestyle changes into everyday life. Both interventions will involve 35 hours of training. Testing will happen before and after treatment, and at 6- and 12-month follow-ups.
Behavioural Intervention
ToolboxDetect Cognitive Screening for Cognitive Impairment
This trial will test a new strategy for detecting cognitive decline in primary care settings. The strategy, called ToolboxDetect, will provide an efficient and sensitive cognitive screen that can be easily implemented in everyday clinical settings.
Monoclonal Antibodies
JNJ-63733657 for Alzheimer's Disease
This trial is testing a new drug called JNJ-63733657 to see if it can help slow down the worsening of symptoms in patients with Alzheimer's disease. The goal is to see if the drug can help maintain brain function and daily living skills better.
Alpha-2 Adrenergic Agonist
Dexmedetomidine for Postoperative Cognitive Dysfunction
This trial is testing whether the drug Dexmedetomidine can prevent postoperative cognitive dysfunction (POCD), which is when patients have trouble thinking and remembering after surgery.
Trials for Alzheimer's Disease Patients
Behavioural Intervention
Cognitive Rehabilitation for Stroke-Related Cognitive Impairment
This trial will compare two approaches to cognitive rehabilitation in adults with stroke and persistent mild to moderate cognitive impairment. One approach will add in-lab training on everyday activities and procedures to transfer improvements to daily life; the other approach will add in-lab training on relaxation, healthy nutrition, and healthy sleep with procedures to promote integration of lifestyle changes into everyday life. Both interventions will involve 35 hours of training. Testing will happen before and after treatment, and at 6- and 12-month follow-ups.
Behavioural Intervention
ToolboxDetect Cognitive Screening for Cognitive Impairment
This trial will test a new strategy for detecting cognitive decline in primary care settings. The strategy, called ToolboxDetect, will provide an efficient and sensitive cognitive screen that can be easily implemented in everyday clinical settings.
Monoclonal Antibodies
JNJ-63733657 for Alzheimer's Disease
This trial is testing a new drug called JNJ-63733657 to see if it can help slow down the worsening of symptoms in patients with Alzheimer's disease. The goal is to see if the drug can help maintain brain function and daily living skills better.
Alpha-2 Adrenergic Agonist
Dexmedetomidine for Postoperative Cognitive Dysfunction
This trial is testing whether the drug Dexmedetomidine can prevent postoperative cognitive dysfunction (POCD), which is when patients have trouble thinking and remembering after surgery.
Trials With No Placebo
Behavioural Intervention
Cognitive Rehabilitation for Stroke-Related Cognitive Impairment
This trial will compare two approaches to cognitive rehabilitation in adults with stroke and persistent mild to moderate cognitive impairment. One approach will add in-lab training on everyday activities and procedures to transfer improvements to daily life; the other approach will add in-lab training on relaxation, healthy nutrition, and healthy sleep with procedures to promote integration of lifestyle changes into everyday life. Both interventions will involve 35 hours of training. Testing will happen before and after treatment, and at 6- and 12-month follow-ups.
Behavioural Intervention
ToolboxDetect Cognitive Screening for Cognitive Impairment
This trial will test a new strategy for detecting cognitive decline in primary care settings. The strategy, called ToolboxDetect, will provide an efficient and sensitive cognitive screen that can be easily implemented in everyday clinical settings.
Alpha-2 Adrenergic Agonist
Dexmedetomidine for Postoperative Cognitive Dysfunction
This trial is testing whether the drug Dexmedetomidine can prevent postoperative cognitive dysfunction (POCD), which is when patients have trouble thinking and remembering after surgery.
Behavioural Intervention
Cognitive Rehabilitation for Traumatic Brain Injury
This trial will assess two different approaches to brain injury rehabilitation delivered remotely via tele-rehabilitation, with the goal of helping Veterans build personal strengths and better accomplish their goals.
View More Related Trials
Frequently Asked Questions
Introduction to mci
What are the top hospitals conducting mci research?
In the quest to better understand and combat Mild cognitive impairment (MCI), several top hospitals have emerged as pioneers in clinical trials. In Toronto, Sunnybrook Health Sciences Centre leads the way with six ongoing MCI trials and a total of 19 groundbreaking studies conducted thus far. Since its first recorded trial in 2010, this esteemed institution has been at the forefront of MCI research, bringing hope to countless individuals affected by cognitive decline.
Meanwhile, Northwestern University in Chicago stands out with its four active MCI trials and a notable history of 16 previous studies. Having initiated their first recorded trial back in 1999, this hospital has remained dedicated to advancing our understanding of MCI for over two decades.
Further south in Nashville, Vanderbilt University Medical Center joins the ranks with four ongoing MCI trials and an impressive track record of 26 completed investigations since their inaugural trial also in 1999. Their commitment to cutting-edge research continues to contribute significantly towards unlocking new insights into this condition.
On the east coast, Wake Forest University Health Sciences is making substantial strides with four active MCI trials and a legacy of 14 previously conducted studies. Their first recorded mci trial took place ten years ago when they began pushing boundaries through innovative approaches towards addressing cognitive impairment.
Last but not least, we find the University of Alabama at Birmingham joining forces against MCI with three current clinical trials and twelve past endeavors under their belt since initiating their pioneering investigation back in2007.The collective efforts showcased by these hospitals demonstrate that progress is being made each day towards unraveling the mysteries surrounding Mild Cognitive Impairment. Through dedication, innovation,and collaboration among medical professionals across various locations worldwide; scientific advancements are being achieved which give renewed hope for finding effective treatments or preventive measures against this challenging condition affecting numerous individuals globally
Which are the best cities for mci clinical trials?
When it comes to clinical trials for MCI (Mild cognitive impairment), several cities stand out as prime destinations. Anchorage, Alaska leads the way with 25 active trials investigating treatments like Bevacizumab, Ramipril, and Intensity-Modulated Radiation Therapy. Boston, Massachusetts follows closely behind with 15 ongoing studies focusing on interventions such as Gemcitabine and JNJ-63733657. New york, New York also offers a wealth of opportunities with 15 active trials exploring treatments like Nicotine Transdermal Patch and Methylphenidate. These cities showcase their commitment to advancing MCI research by providing access to cutting-edge clinical trials that have the potential to improve patient outcomes and enhance our understanding of this condition.
Which are the top treatments for mci being explored in clinical trials?
Clinical trials are actively exploring various treatments for mild cognitive impairment (MCI). The top contenders in this field include:
- Exercise, which is currently being investigated in two active MCI trials. Since its introduction in 2006, it has been a relatively popular treatment option with a total of 18 clinical trials dedicated to MCI.
- Dexmedetomidine Hydrochloride Group, an emerging player with two ongoing MCI trials since its debut in 2018. Although still relatively new, it shows promise as a potential treatment option.
- Memantine, another notable candidate that is currently involved in two active MCI studies. It first entered the scene back in 2004 and has accumulated a respectable number of 13 clinical trials focused on treating MCI.
As researchers delve deeper into these investigations, they bring us closer to finding effective solutions for individuals living with mild cognitive impairment.
What are the most recent clinical trials for mci?
Recent clinical trials have provided valuable insights into the management of mild cognitive impairment (MCI). Phase 4 trial results indicate that methylphenidate may hold promise in addressing MCI symptoms. Another noteworthy study, conducted during Phase 1, focused on evaluating the effectiveness of Treatment Arm (1) for individuals with MCI. Furthermore, researchers explored the potential benefits of psilocybin at a dose of 1.5 mg in patients with MCI during a Phase 2 trial. Additionally, another Phase 2 trial investigated CI-581a+CI-581b as a potential treatment option for MCI. Finally, an ongoing Phase 4 trial is examining Condition 2 to further understand its impact on managing this condition. These diverse studies contribute significantly to our understanding and future approaches towards tackling MCI effectively.
What mci clinical trials were recently completed?
In recent years, several clinical trials investigating potential treatments for MCI have been completed. These trials include one sponsored by Merck Sharp & Dohme Corp., assessing the effectiveness of Donepezil and concluding in March 2021. Another trial, led by Massachusetts General Hospital, focused on Bacillus Calmette-Guerin (BCG) therapy and was also completed in March 2021. In July 2020, Sage Therapeutics wrapped up a trial evaluating SAGE-718. While these studies offer valuable insights into potential interventions for MCI, it is important to continue research efforts to further advance our understanding and treatment options for this condition.