Role of Desloratadine in Reducing Inflammation From Occupational Heat Strain
Palo Alto (17 mi)Overseen byLynneth Stuart-Hill, PhD
Age: 18 - 65
Sex: Male
Travel: May be covered
Time Reimbursement: Varies
Trial Phase: N/A
Waitlist Available
Sponsor: University of Victoria
No Placebo Group
Trial Summary
What is the purpose of this trial?This trial investigates whether desloratadine can reduce inflammation in firefighters exposed to high heat. Firefighters often face extreme temperatures that can cause harmful inflammation. Desloratadine, typically used for allergies, may help by stabilizing certain cells in the body. Desloratadine also has anti-inflammatory activity.
Eligibility Criteria
Treatment Details
3Treatment groups
Experimental Treatment
Group I: No InterventionExperimental Treatment1 Intervention
No intervention: neither drug nor placebo
Group II: Inert PlaceboExperimental Treatment1 Intervention
Placebo 10mg compounded to oral pill
Group III: DesloratadineExperimental Treatment1 Intervention
Desloratadine (Aerius) 10mg compounded to oral pill
Find a clinic near you
Research locations nearbySelect from list below to view details:
University of VictoriaVictoria, Canada
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Who is running the clinical trial?
University of VictoriaLead Sponsor