~2 spots leftby Jul 2025

Observational Study of HIV+ Deceased Donor Transplant for HIV+ Recipients

Recruiting in Palo Alto (17 mi)
+12 other locations
CD
Overseen byChristine Durand, MD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Recruiting
Sponsor: Johns Hopkins University
No Placebo Group

Trial Summary

What is the purpose of this trial?

HIV-infected (HIV+) individuals who agree to accept and receive a solid organ transplant from an HIV+ deceased donor will be followed to determine the safety and efficacy of this practice. Some HIV+ individuals who receive a solid organ transplant from HIV-uninfected (HIV-) donors will also be followed.

Research Team

CD

Christine Durand, MD

Principal Investigator

Johns Hopkins University

Eligibility Criteria

Inclusion Criteria

All individuals with end-stage organ disease and HIV infection who meet standard clinical criteria for transplantation and the study inclusion

Treatment Details

Interventions

  • HIV-infected deceased donor organ (Virus Therapy)
Participant Groups
2Treatment groups
Experimental Treatment
Group I: HIV D-/R+Experimental Treatment0 Interventions
HIV-infected individuals who accept an organ from an HIV-uninfected deceased donor
Group II: HIV D+/R+Experimental Treatment1 Intervention
HIV-infected individuals who accept an organ from an HIV-infected deceased donor

Find a Clinic Near You

Who Is Running the Clinical Trial?

Johns Hopkins University

Lead Sponsor

Trials
2,366
Recruited
15,160,000+
Theodore DeWeese profile image

Theodore DeWeese

Johns Hopkins University

Chief Executive Officer since 2023

MD from an unspecified institution

Allen Kachalia profile image

Allen Kachalia

Johns Hopkins University

Chief Medical Officer since 2023

MD from an unspecified institution

University of Maryland, Institute of Human Virology

Collaborator

Trials
1
Recruited
130+

Emory University

Collaborator

Trials
1,735
Recruited
2,605,000+
Dr. R. Donald Harvey profile image

Dr. R. Donald Harvey

Emory University

Chief Medical Officer

MD from Emory University School of Medicine

Dr. George Painter profile image

Dr. George Painter

Emory University

Chief Executive Officer since 2013

PhD in Synthetic Organic Chemistry from Emory University

University of Maryland

Collaborator

Trials
171
Recruited
325,000+
Mr. Pearson profile image

Mr. Pearson

University of Maryland

Chief Executive Officer since 2019

B.S. in Business Administration from the University of Delaware, B.S. in Accounting from the University of Maryland University College, M.S. in Finance from Loyola University

Dr. Stuart McIntosh profile image

Dr. Stuart McIntosh

University of Maryland

Chief Medical Officer

MD

Methodist Health System

Collaborator

Trials
156
Recruited
4,826,000+
James C. Scoggin, Jr. profile image

James C. Scoggin, Jr.

Methodist Health System

Chief Executive Officer since 2019

BBA in Finance from Texas A&M University

Martin L. Koonsman profile image

Martin L. Koonsman

Methodist Health System

Chief Medical Officer

MD from Texas Tech University School of Medicine

Columbia University

Collaborator

Trials
1,529
Recruited
2,832,000+
Dr. Katrina Armstrong profile image

Dr. Katrina Armstrong

Columbia University

Chief Executive Officer

MD from Johns Hopkins University, MS in Epidemiology from Harvard School of Public Health

Dr. Katrina Armstrong profile image

Dr. Katrina Armstrong

Columbia University

Chief Medical Officer

MD from Harvard Medical School

Icahn School of Medicine at Mount Sinai

Collaborator

Trials
933
Recruited
579,000+
Dr. Brendan Carr profile image

Dr. Brendan Carr

Icahn School of Medicine at Mount Sinai

Chief Executive Officer since 2024

MD, MA, MS

Dr. Vicki LoPachin profile image

Dr. Vicki LoPachin

Icahn School of Medicine at Mount Sinai

Chief Medical Officer

MD, FACP, MBA

Weill Medical College of Cornell University

Collaborator

Trials
1,103
Recruited
1,157,000+
Dr. Robert Min profile image

Dr. Robert Min

Weill Medical College of Cornell University

Chief Executive Officer since 2024

MD, MBA

Dr. Adam R. Stracher profile image

Dr. Adam R. Stracher

Weill Medical College of Cornell University

Chief Medical Officer since 2024

MD

Georgetown University

Collaborator

Trials
355
Recruited
142,000+
Dr. Ivica Labuda profile image

Dr. Ivica Labuda

Georgetown University

Chief Executive Officer since 2022

PhD in Biochemistry and Molecular & Cellular Biology from Slovak Academy of Sciences, University of Graz, and Rutgers University

Dr. Richard Ascione profile image

Dr. Richard Ascione

Georgetown University

Chief Medical Officer since 2023

MD from Georgetown University Medical School

University of Colorado, Denver

Collaborator

Trials
1,842
Recruited
3,028,000+
Aviva Abosch profile image

Aviva Abosch

University of Colorado, Denver

Chief Medical Officer since 2019

MD

Uday B. Kompella profile image

Uday B. Kompella

University of Colorado, Denver

Chief Executive Officer since 2015

PhD in Pharmaceutical Sciences