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Virus Therapy

HIV D-/R+ for HIV/AIDS

N/A
Recruiting
Led By Christine Durand, MD
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
All individuals with end-stage organ disease and HIV infection who meet standard clinical criteria for transplantation and the study inclusion
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion, up to 4 years
Awards & highlights
No Placebo-Only Group

Summary

HIV-infected (HIV+) individuals who agree to accept and receive a solid organ transplant from an HIV+ deceased donor will be followed to determine the safety and efficacy of this practice. Some HIV+ individuals who receive a solid organ transplant from HIV-uninfected (HIV-) donors will also be followed.

Eligible Conditions
  • HIV/AIDS

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~one year, two years, 3 years, 4 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and one year, two years, 3 years, 4 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Survival
Secondary study objectives
Antiretroviral resistance and X4 tropic virus
Graft rejection
Graft survival
+8 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: HIV D-/R+Experimental Treatment0 Interventions
HIV-infected individuals who accept an organ from an HIV-uninfected deceased donor
Group II: HIV D+/R+Experimental Treatment1 Intervention
HIV-infected individuals who accept an organ from an HIV-infected deceased donor

Find a Location

Who is running the clinical trial?

University of Maryland, Institute of Human VirologyUNKNOWN
Emory UniversityOTHER
1,691 Previous Clinical Trials
2,603,691 Total Patients Enrolled
University of MarylandOTHER
165 Previous Clinical Trials
304,465 Total Patients Enrolled
~9 spots leftby Jul 2025
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