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Probiotic

Spiced Yogurt for Metabolic Health

N/A
Recruiting
Research Sponsored by University of Alabama, Tuscaloosa
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up pre/post each four-week study arm

Summary

This trial aims to study how spices can help promote a healthy gut by acting as prebiotics. The researchers are looking to understand the effects of spice-derived compounds on the gut and overall health. They

Who is the study for?
This trial is for individuals with Metabolic Syndrome or Cardiometabolic Syndrome. Specific eligibility criteria are not provided, but typically participants should be adults who meet the diagnostic criteria for these conditions and are able to consume yogurt.
What is being tested?
The study is testing whether adding spices to yogurt can improve gut health and cardiometabolic profile by acting as a prebiotic. The effects on gut microbiota and related metabolic outcomes will be measured before and after consuming the spiced yogurt.
What are the potential side effects?
While specific side effects are not listed, common ones may include digestive discomfort such as bloating or gas due to changes in gut bacteria from the prebiotic effect of spices.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~pre/post each four-week study arm
This trial's timeline: 3 weeks for screening, Varies for treatment, and pre/post each four-week study arm for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Concentration of fecal short chain fatty acids including acetate, proprionate, and butyrate
Concentration of serum ghrelin (pg/mL)
Concentration of serum leptin
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Intervention Arm - Yogurt with added SpicesExperimental Treatment1 Intervention
Consumption of twice daily yogurt with added spices for four weeks.
Group II: Sham Arm - Yogurt without added SpicesPlacebo Group2 Interventions
Consumption of twice daily yogurt without added spices for four weeks.

Find a Location

Who is running the clinical trial?

McCormick Science InstituteOTHER
11 Previous Clinical Trials
1,149 Total Patients Enrolled
University of Alabama, TuscaloosaLead Sponsor
47 Previous Clinical Trials
17,761 Total Patients Enrolled
~10 spots leftby Dec 2025
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