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One (1) TMS treatment per day plus CBT-I for Mild Cognitive Impairment

N/A

Waitlist Available

Research Sponsored by Beth Israel Deaconess Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

* Aged 65 years or older

* Speak and read English

Timeline

Screening 3 weeks

Treatment Varies

Follow Up week 3, week 13, 6 months

Summary

The goal of this study is to test a new way to improve sleep quality in persons living with mild cognitive impairment. The treatment combines a safe and gentle way to stimulate the brain, called transcranial magnetic stimulation, with a psychological treatment, called cognitive behavioral therapy for insomnia.

Eligible Conditions

Mild Cognitive Impairment
Insomnia

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ week 3, week 13, 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~week 3, week 13, 6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and week 3, week 13, 6 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Insomnia Severity Index

Paired Associative Learning test (CANTAB)

Spatial Working Memory test (CANTAB)

Secondary study objectives

Center for Epidemiologic Studies Depression scale

Match to Sample Visual Search test (CANTAB)

Multidimensional Fatigue Symptoms Inventory

+7 more

Other study objectives

Cortical Plasticity

Trial Design

2Treatment groups

Active Control

Group I: One (1) TMS treatment per day plus CBT-IActive Control2 Interventions

One (1) daily treatment of intermittent theta-burst stimulation (iTBS) applied to the left dorsolateral prefrontal cortex (L-DLPFC) for 10 days (2 weeks) followed by a 9-week Internet-delivered cognitive behavioral therapy for insomnia (CBT-I) program

Group II: Two (2) TMS treatments per day plus CBT-IActive Control2 Interventions

Two (2) daily treatments, spaced 1 hour apart, of intermittent theta-burst stimulation (iTBS) applied to the left dorsolateral prefrontal cortex (L-DLPFC) for 10 days (2 weeks) followed by a 9-week Internet-delivered cognitive behavioral therapy for insomnia (CBT-I) program

0 / 6Eligibility criteria met