Multiple Myeloma (MM) Quality of Life (QOL) Study

Recruiting in Palo Alto (17 mi)

+2 other locations

Overseen by Elizabeth K O'Donnell, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Massachusetts General Hospital

No Placebo Group

Trial Summary

What is the purpose of this trial?

The main purpose of this study is to examine differences in quality of life and psychological distress for both Multiple Myeloma patients receiving treatment and their caregivers and to assess patient and caregiver prognostic understanding (understanding of the likely course of a disease over time) of Multiple Myeloma to guide development of more personalized treatment plans. This study looks to further understand quality of life changes throughout multiple myeloma therapy for both patients and caregivers to help determine ways to improve patient and caregiver understanding of illness and in turn, tailor customized treatment that best aligns with patient preferences. The study will use a series of questionnaires to measure quality of life, mood, coping strategies, and prognostic understanding.

Eligibility Criteria

Inclusion Criteria

Adult patients (greater than 18 years) receiving active therapy for MM.

For patients with newly diagnosed MM, patients are eligible while undergoing induction therapy prior to received autologous stem cell transplant but not after.

Ability to read questions in English or willing to complete questionnaires with the assistance of an interpreter.

Treatment Details

Interventions

• Questionnaire (Behavioral Intervention)

Participant Groups

Group I: Newly Diagnosed MM 1st Line and Caregivers Experimental Treatment 1 Intervention

This research study's procedures include screening for eligibility, participant designation of a caregiver and a series of questionnaires. * Patients will be asked to identify a caregiver (e.g. a relative or friend) upon whom they rely for help and has an in-person contact with the patient at least 2x per week. * Both patients with or without identified caregivers will complete a one time series of questionnaires. * The questionnaires are completed one time only and measure quality of life, mood, coping strategies, and prognostic understanding and can be completed in the hospital, clinic, over the email, or telephone with assistance provided as needed.Questionnaires take approximately 20 minutes to complete.

Group II: MM receiving 1-3 prior lines of therapy and Caregivers Experimental Treatment 1 Intervention

This research study's procedures include screening for eligibility, participant designation of a caregiver and a series of questionnaires. * Patients will be asked to identify a caregiver (e.g. a relative or friend) upon whom they rely for help and has an in-person contact with the patient at least 2x per week. * Both patients with or without identified caregivers will complete a one time series of questionnaires. * The questionnaires are completed one time only and measure quality of life, mood, coping strategies, and prognostic understanding and can be completed in the hospital, clinic, over the email, or telephone with assistance provided as needed.Questionnaires take approximately 20 minutes to complete

Group III: MM patients receiving ≥ 4 lines of therapy and Cargivers Experimental Treatment 1 Intervention

This research study's procedures include screening for eligibility, participant designation of a caregiver and a series of questionnaires. * Patients will be asked to identify a caregiver (e.g. a relative or friend) upon whom they rely for help and has an in-person contact with the patient at least 2x per week. * Both patients with or without identified caregivers will complete a one time series of questionnaires. * The questionnaires are completed one time only and measure quality of life, mood, coping strategies, and prognostic understanding and can be completed in the hospital, clinic, over the email, or telephone with assistance provided as needed.Questionnaires take approximately 20 minutes to complete

Find a Clinic Near You

Research Locations Nearby Select from list below to view details:

Massachusetts General Hospital Cancer Center Boston, MA

Dana-Farber Cancer Institute Boston, MA

Beth Israel Deaconess Medical Center Boston, MA

Who Is Running the Clinical Trial?

Massachusetts General Hospital Lead Sponsor

Kully Family Foundation Collaborator

References