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Procedure

Automated vs Fixed Oxygen Therapy for Chronic Respiratory Disease

N/A

Recruiting

Research Sponsored by West Park Healthcare Centre

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Current prescription for supplemental oxygen therapy

Be older than 18 years old

Must not have

Inability to communicate in English

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 24 hour

Awards & highlights

No Placebo-Only Group

Summary

This trial is comparing two ways to give oxygen to people w/ chronic respiratory disease to see if one is better. FixedO2 vs AutoO2. Goal is to keep oxygen levels (SpO2) in the target range of 92-96%.

Who is the study for?

This trial is for people with stable chronic respiratory diseases who are already on prescribed oxygen therapy. Participants must be able to communicate in English and should not have any issues that could affect the accuracy of oximetry readings.

What is being tested?

The study compares two methods of oxygen delivery: AutoO2, which adjusts oxygen flow automatically based on real-time needs using pulse oximetry, and FixedO2, a standard method with preset oxygen levels for different activities.

What are the potential side effects?

Potential side effects may include discomfort from wearing the device used to measure SpO2 or skin irritation. There might also be risks associated with incorrect oxygen levels due to machine error.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am currently prescribed supplemental oxygen.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I cannot communicate in English.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 24 hour

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~24 hour

This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 hour for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Daily time spent normoxic as defined by an arterial oxygen saturation measured by pulse oximetry (SpO2), between 92 to 96%, will be expressed a function of total time recorded SpO2.

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: AutoO2Experimental Treatment1 Intervention

Automated Titration of Oxygen (Auto-O2) using a closed-loop system in which the oxygen flow to the participant is continuously adjusted on the basis of pulse oximetry signals to maintain a target range of oxygen saturation to meet the patient's immediate needs.

Group II: FixedO2Active Control1 Intervention

Fixed flow oxygen delivery administered using manual flow meters according to standard clinical procedures.

0 / 2Eligibility criteria met