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Cognitive Training
Community-Based Cognitive Training in Early Schizophrenia (COTES Trial)
San Francisco, CA
N/A
Waitlist Available
Led By Sophia Vinogradov, MD
Research Sponsored by University of California, San Francisco
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, post-training, 6 month follow-up
Awards & highlights
No Placebo-Only Group
Summary
The purpose of this study is to determine whether cognitive training exercises can improve cognitive functioning in young patients with recent-onset schizophrenia, schizoaffective, schizophreniform, and psychosis NOS who are being treated in community mental health settings. We will investigate the effects of web-based cognitive training exercises delivered on a portable laptop computer. The findings will provide us with valuable information on whether cognitive training can improve the cognition and functioning of young individuals early in the course of schizophrenia.
Eligible Conditions
- Schizophrenia
- Psychosis
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline, post-training, 6 month follow-up
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, post-training, 6 month follow-up
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Auditory Processing Speed
Functioning
Neurocognition
+1 moreSecondary study objectives
Functional Capacity
Internalized Stigma
Social Functioning
Other study objectives
Feasibility and Acceptability
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
3Treatment groups
Experimental Treatment
Active Control
Group I: Targeted Cognitive Training - TCTExperimental Treatment1 Intervention
Neuroadaptive cognitive training
Group II: General Cognitive Exercises (GCE)Experimental Treatment1 Intervention
Neuroadaptive cognitive training
Group III: Treatment as UsualActive Control1 Intervention
Treatment as Usual
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Neuroadaptive cognitive training
2013
Completed Phase 2
~470
Find a Location
Closest Location:Prevention and Recovery in Early Psychosis (PREP) Program· San Francisco, CA
Who is running the clinical trial?
University of California, San FranciscoLead Sponsor
2,616 Previous Clinical Trials
17,771,527 Total Patients Enrolled
17 Trials studying Schizophrenia
1,708 Patients Enrolled for Schizophrenia
Sophia Vinogradov, MDPrincipal InvestigatorUniversity of California, San Francisco
13 Previous Clinical Trials
3,262 Total Patients Enrolled
10 Trials studying Schizophrenia
1,555 Patients Enrolled for Schizophrenia