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Problem Solving Therapy for Suicide Prevention in Veterans

N/A
Recruiting
Led By Sherry A Beaudreau, PhD
Research Sponsored by VA Office of Research and Development
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
No current prescription for anti-psychotics if prescribed for a psychotic disorder
>= 60 years old
Must not have
Current prescription for anti-psychotics if prescribed for a psychotic disorder, and not prescribed for depression without psychosis
Diagnosis of dementia; evidence that cognitive impairment is indicative of possible dementia based on a positive cognitive telephone screen (>=10 errors on the Blessed cognitive screen)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change across 11 timepoints: baseline, after each of the 6 weekly treatment sessions, posttreatment (7 weeks), 1-, 3-, and 6-month follow-up.
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to help older Veterans at risk for suicide by teaching them problem-solving skills and providing safety planning. The goal is to see if this method can better reduce suicidal thoughts and increase reasons for living.

Who is the study for?
This trial is for older Veterans (60+) with depression, anxiety, PTSD or similar conditions who have had suicidal thoughts but are not at imminent risk. They must be able to understand English and participate in therapy without severe cognitive impairment from dementia or recent head injury. Those with certain psychiatric disorders, substance abuse issues, unstable medical conditions, or currently in individual psychotherapy are excluded.
What is being tested?
The study compares usual VA care for suicide prevention with an addition of Problem Solving Therapy (PST) to see if it better reduces suicide risk among older Veterans. PST aims to improve coping strategies and has shown promise in pilot studies for reducing late-life suicide risk.
What are the potential side effects?
Problem Solving Therapy may cause emotional discomfort as individuals confront personal challenges during sessions. There might also be temporary increases in distress as participants learn new problem-solving skills.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am not currently taking anti-psychotics for a psychotic disorder.
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I am 60 years old or older.
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I have been diagnosed with depression, anxiety, PTSD, or similar conditions.
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I have been diagnosed with depression, anxiety, or PTSD.
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I have not had a head injury in the last year.
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I do not have any severe or unstable long-term illnesses.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I am currently taking anti-psychotics for a psychotic disorder, not just for depression.
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I have been diagnosed with dementia based on a cognitive phone test.
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I do not have depression, anxiety, or PTSD.
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I do not have any severe or unstable chronic illnesses.
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I am younger than 60 years old.
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My senses (sight, hearing, etc.) are not good enough for tests or treatment.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change across 11 timepoints: baseline, after each of the 6 weekly treatment sessions, posttreatment (7 weeks), 1-, 3-, and 6-month follow-up.
This trial's timeline: 3 weeks for screening, Varies for treatment, and change across 11 timepoints: baseline, after each of the 6 weekly treatment sessions, posttreatment (7 weeks), 1-, 3-, and 6-month follow-up. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Geriatric Suicide Ideation Scale (GSIS)
Reasons for Living - Older Adult Scale (Short RFL-OA)
Secondary study objectives
DKEFS Verbal Fluency Test
Oral Trail Making Test (OTMT)
WAIS Digit Span subtest (Digits Forward and Backward)
+1 more
Other study objectives
Suicide attempts

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Active treatment plus EUCExperimental Treatment1 Intervention
Veterans randomized to this condition received the treatment plus EUC.
Group II: Enhanced Usual Care (EUC)Active Control1 Intervention
Active comparator (EUC only).

Find a Location

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor
1,664 Previous Clinical Trials
3,765,633 Total Patients Enrolled
Sherry A Beaudreau, PhDPrincipal InvestigatorVA Palo Alto Health Care System, Palo Alto, CA
1 Previous Clinical Trials
10 Total Patients Enrolled
Sherry Ann Beaudreau, PhDPrincipal InvestigatorVA Palo Alto Health Care System, Palo Alto, CA

Media Library

Problem Solving Therapy (PST) plus EUC Clinical Trial Eligibility Overview. Trial Name: NCT04763330 — N/A
Suicidal Thoughts Research Study Groups: Enhanced Usual Care (EUC), Active treatment plus EUC
Suicidal Thoughts Clinical Trial 2023: Problem Solving Therapy (PST) plus EUC Highlights & Side Effects. Trial Name: NCT04763330 — N/A
Problem Solving Therapy (PST) plus EUC 2023 Treatment Timeline for Medical Study. Trial Name: NCT04763330 — N/A
~48 spots leftby Mar 2026