Intermittent Catheter for Urinary Retention

(ConCaRe™ Trial)

BK
SW
MJ
Overseen ByMackenzie Juckett
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Hollister Incorporated
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial focuses on understanding the experiences of people using intermittent catheters to manage urinary retention or incomplete bladder emptying. The goal is to gather information from participants about their current catheter use and any challenges or benefits they encounter. As an observational study, it records participants' experiences without altering their treatment. This trial suits adults who use intermittent catheters and are willing to share their experiences through regular online questionnaires. As an unphased trial, it offers participants the chance to contribute valuable insights that could enhance future care for catheter users.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It focuses on self-reporting about catheter use, so it's likely you can continue your medications, but you should confirm with the trial organizers.

What prior data suggests that intermittent catheters are safe for managing urinary retention?

Research shows that intermittent catheters are generally safe for adults needing assistance with urinary retention. Studies have found that these catheters reduce the risk of urinary tract infections compared to other methods. Some research suggests that specially coated catheters, such as prelubricated or hydrophilic ones, offer even greater safety for long-term use. Overall, patients using intermittent catheters report fewer changes in their urinary tract, indicating good safety.12345

Why are researchers excited about this trial?

Unlike traditional indwelling catheters that remain in the bladder, intermittent catheters are used temporarily and removed after each use, reducing the risk of infection and complications. Researchers are excited about intermittent catheters because they offer more control and comfort, allowing individuals to manage their bladder on their own schedule. This method also has the potential to improve quality of life by minimizing the need for continuous catheterization and healthcare support.

What evidence suggests that using an intermittent catheter is effective for managing urinary retention?

Studies have shown that intermittent catheters effectively manage urinary retention. One study found that patients using these catheters had significantly less residual urine in their bladders. Another study reported that normal bladder function returned in about 36% to 44% of patients using intermittent catheters. Over time, many patients improved their ability to empty their bladders, with some no longer needing catheters. This evidence suggests that intermittent catheters can be a reliable option for managing urinary retention.23467

Who Is on the Research Team?

DN

Diane Newman, D.N.P. F.A.A.N. B.C.B.-P.M.D.

Principal Investigator

University of Pennsylvania

JS

Jessica Simmons, DNP, APRN, FNP-C, CWON, DNC

Principal Investigator

Hollister Incorporated

Are You a Good Fit for This Trial?

Inclusion Criteria

Is performing transurethral intermittent catheterization.
Uses intermittent catheter(s) from any manufacturer as a form of management for urinary retention or incomplete bladder emptying.
Must be able to provide informed consent and have no cognitive impairment that would hinder the ability to provide informed consent or self-reported data.
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Data Collection

Participants self-report on attributes of their prescribed intermittent catheters and various aspects of using an intermittent catheter

5 years

Follow-up

Participants are monitored for safety and effectiveness after data collection

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Intermittent Catheter

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Standard of CareExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Hollister Incorporated

Lead Sponsor

Trials
14
Recruited
6,200+

Parexel

Industry Sponsor

Trials
322
Recruited
137,000+
Peyton Howell profile image

Peyton Howell

Parexel

Chief Executive Officer

Master of Healthcare Administration from The Ohio State University, Bachelor of Arts in Health Communications from the University of Illinois

Dr. Austin Smith profile image

Dr. Austin Smith

Parexel

Chief Medical Officer since 2023

MD from the Royal College of Surgeons in Ireland

Technomics Research

Industry Sponsor

Trials
5
Recruited
880+

Citations

Effects of clean intermittent catheterization and transurethral ...

The results revealed that the residual urine volume was markedly lower in patients with urinary retention who received intermittent ...

Effectiveness and safety of intermittent catheterisation for the ...

Normal voiding was restored in 25 (35.7%) patients in group I and 26 (44%) patients in group II. The point estimate of the probability of ...

A Real-world Data Analysis of Intermittent Catheterization ...

The primary outcome measures were the proportion of patients with at least one ssUTI (prescription of a nonspecific antibiotic with a UTI-related diagnosis, ...

Urinary Retention Evaluation and Catheterization ...

A UR evaluation and catheterization algorithm was developed to improve patient safety by increasing appropriate use of bladder scanners and catheterization.

Intermittent Catheters

The probability of bladder voiding function recovery and arrest of self-catheterization was 24.5%, 54%, 59%, 72%, and 77% at 4, 8, 12, 52, and 78 weeks, ...

Intermittent Catheters for Chronic Urinary Retention: A Health ...

This review evaluates the effectiveness, safety, patient preference, cost-effectiveness, and budget impact of different types of intermittent catheter (IC).

VIII. Evidence Review | Infection Control

Studies of patients with neurogenic bladder most consistently found a decreased risk of CAUTI with intermittent catheterization.