Popular Trials
Behavioural Intervention
Exercise + BH4 for Heart Failure
This trial is studying how impaired muscle blood flow contributes to exercise intolerance in Veterans with heart failure and a reduced ejection fraction. They hope to develop strategies for restoring exercise tolerance and slowing disease progression in this patient group.
Behavioural Intervention
Acipimox + Empagliflozin for Heart Failure and Type 2 Diabetes
This trial will look at how a certain type of medication affects people with type 2 diabetes and heart failure. The medication may provide extra fuel for the heart and improve its function. The researchers will measure
Behavioural Intervention
Ketone Ester for Heart Failure
This trial is looking at how a ketone drink can impact exercise capacity and other heart-related factors in patients with heart failure. Patients with heart failure often struggle with fatigue and shortness of breath, limiting
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Trials With No Placebo
CAR T-cell Therapy
CAR T-Cell Therapy for Pediatric Cancer
This trial is for patients ≤ 21 years old with relapsed/refractory B7-H3+ solid tumors, investigating the use of autologous T cells genetically engineered to express B7-H3-CARs. The study will evaluate the safety and maximum tolerated dose of B7-H3-CAR T cells.
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Frequently Asked Questions
Introduction to adrenal insufficiency
What are the top hospitals conducting adrenal insufficiency research?
Although adrenal insufficiency may not be as widely known as other medical conditions, there are hospitals dedicated to pushing the boundaries of research and treatment in this field. One such hospital is Montefiore Medical Center located in the Bronx. Currently, they have one active clinical trial specifically focused on adrenal insufficiency, highlighting their commitment to advancing knowledge and improving outcomes for patients with this condition. What sets Montefiore apart is that they were also the first to record an adrenal insufficiency trial in 2022. This pioneering effort demonstrates their determination to explore new avenues of understanding and potential treatments for adrenal insufficiency, which affects individuals when their adrenal glands do not produce enough hormones essential for bodily functions.
Located at a prime location within New york City, Montefiore Medical Center's dedication showcases why it has become a renowned institution in healthcare research and patient care. By prioritizing clinical trials related to adrenal insufficiency, they aim to enhance our knowledge base about this lesser-known condition while striving towards better management strategies and potentially groundbreaking therapies. The efforts of institutions like Montefiore allow us to envision a future where those living with adrenal insufficiency can experience improved quality of life through innovative interventions derived from cutting-edge research conducted right here in the Bronx.
Which are the best cities for adrenal insufficiency clinical trials?
When it comes to clinical trials for adrenal insufficiency, the Bronx in New york takes center stage with one active trial. This study focuses on patients who are suspected to have adrenal insufficiency and aims to provide valuable insights into diagnosis and treatment options. While other cities may have more ongoing trials in different areas of research, the Bronx offers a unique opportunity for individuals dealing specifically with this condition to participate in cutting-edge research that can potentially improve their quality of life.
Which are the top treatments for adrenal insufficiency being explored in clinical trials?
In the realm of adrenal insufficiency, clinical trials focus on uncovering innovative treatments. Leading the charge is osilodrostat—a promising drug currently being explored in four active trials for this condition. Another contender gaining attention is levoketoconazole, which has shown potential and is under investigation in three ongoing clinical studies. These two treatments stand out among others, offering hope for improved management of adrenal insufficiency symptoms and quality of life for patients affected by this disorder.
What are the most recent clinical trials for adrenal insufficiency?
Recent clinical trials have brought hope for individuals with adrenal insufficiency. One noteworthy study explores the efficacy of a potential new treatment called CBP-307, which aims to restore hormone levels and alleviate symptoms associated with adrenal insufficiency. Another trial focuses on the use of gene therapy as a promising approach to address the underlying causes of this condition. These advancements in research offer promising possibilities for improved management and outcomes for those affected by adrenal insufficiency.
What adrenal insufficiency clinical trials were recently completed?
Recently, a number of clinical trials investigating adrenal insufficiency have been completed, bringing us closer to advancements in the treatment of this condition. These trials include research on innovative therapies such as Uproleselan and mRNA-1273, sponsored by Washington University School of Medicine and the National Cancer Institute respectively. Another significant trial was conducted by AgenTus Therapeutics in their study on agenT-797. By analyzing these results, researchers hope to enhance our understanding of adrenal insufficiency and develop more effective treatments for patients suffering from this disorder.