Popular Trials
Diuretic
Extended Release Torsemide for Overactive Bladder in Heart Failure
"This trial is comparing two types of the drug torsemide to see which one is better at reducing Overactive Bladder symptoms in patients with chronic heart failure. Patients will be monitored for eight weeks with
Gene Therapy
Gene Therapy for Diastolic Heart Failure
This trial tests a new gene therapy for people with a type of heart failure where the heart struggles to relax and fill with blood. The therapy is given through an infusion directly into the heart. Researchers want to see if it helps the heart work better and if it is safe for patients. Gene therapy has shown promise in treating heart failure, with improvements making it safer and more effective.
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Trials for CHF Patients
Virus Therapy
NAN-101 for Heart Failure
This trial tests a new heart treatment given directly into the heart's blood vessels. It aims to help patients with severe heart failure who have significant symptoms and limited physical activity. The treatment is designed to improve heart function and quality of life.
Compression Stockings
Compression Stockings for Congestive Heart Failure
"This trial is looking at whether tight compression socks or soft compression socks are more effective in preventing swelling and skin changes in patients with congestive heart failure. Participants will be randomly assigned to wear either type of
Not applicable
Aortix Device for Heart Failure
This trial tests a device called Aortix that helps the heart pump blood better. It targets patients with severe heart failure who don't get better with usual treatments. The device works by helping the heart move blood more efficiently.
Ventricular Restoration System
AccuCinch System for Heart Failure
This trial is testing a new device called the AccuCinch Ventricular Restoration System in patients with a specific type of heart failure. The device helps the heart pump blood more effectively by supporting and reshaping its lower chamber. The study aims to see if this device, combined with standard medical treatment, is safe and effective. The CorCap Cardiac Support Device (CSD) is a predecessor that has shown safety and effectiveness in improving left ventricular structure and function in heart failure patients.
Trials for Heart Failure Patients
Phytochemical
Sulforaphane for Heart Failure
This trial tests if a broccoli extract called Sulforaphane can help older adults with a certain type of heart failure. The extract may protect the heart by reducing damage and inflammation. Sulforaphane is a compound derived from vegetables like broccoli, known for its anti-inflammatory and antioxidant properties.
Behavioral Intervention
Respiratory Training for Heart Failure
This trial tests a breathing therapy for heart failure patients with reduced heart function. The therapy includes using a breathing app and coaching to improve respiratory function and heart health.
Cardiac Contractility Modulation
CCM Therapy for Heart Failure
This trial tests a device that helps the heart pump better in patients with moderate heart failure. It targets those whose heart's pumping ability is moderately reduced. The device works by giving the heart small electrical boosts. Several new devices for the treatment of heart failure patients have been introduced and are increasingly used in medical practice or are under evaluation.
Trials With No Placebo
Behavioral Intervention
Respiratory Training for Heart Failure
This trial tests a breathing therapy for heart failure patients with reduced heart function. The therapy includes using a breathing app and coaching to improve respiratory function and heart health.
Behavioural Intervention
LLTS for Atrial Fibrillation
This trial tests a treatment called LLTS, which uses gentle electrical impulses on the ear to help reduce irregular heartbeats and inflammation. It targets healthy volunteers, AF patients, and HFpEF patients. The treatment works by calming the heart and reducing inflammation through vagus nerve stimulation. Low-level tragus stimulation (LLTS) has been shown to significantly reduce atrial fibrillation (AF) burden in patients with paroxysmal AF.
Virus Therapy
NAN-101 for Heart Failure
This trial tests a new heart treatment given directly into the heart's blood vessels. It aims to help patients with severe heart failure who have significant symptoms and limited physical activity. The treatment is designed to improve heart function and quality of life.
View More Related Trials
Frequently Asked Questions
Introduction to congestive heart failure
What are the top hospitals conducting congestive heart failure research?
When it comes to pioneering research and clinical trials in the field of congestive heart failure, several top-notch hospitals are making significant contributions. Weill Cornell Medicine, located in the heart of New York City, is currently conducting two active trials focused on this condition. While their overall number of congestive heart failure studies may be relatively small at four, they have only recently recorded their first trial in 2021. Similarly situated in an esteemed medical hub, the Hospital of the University of Pennsylvania in Philadelphia has two ongoing congestive heart failure trials and a total of four completed trials under their belt since initiating research efforts back in 2015.
Heading westward to Cleveland's University Hospitals Cleveland Medical Center, researchers there are also actively engaged with two current congestive heart failure trials as part of their continued dedication towards advancing knowledge about this complex condition. Their previous investigations have amounted to three conducted studies since embarking on their first trial journey in 2018.
Meanwhile, Massachusetts General Hospital located amidst Boston’s renowned medical community has emerged as another key player with its own pair of active congestive heart failure clinical trials alongside having previously executed just two experiments thus far from making initial entry into these cases around last year i.e., 2020.Unexpectedly yet impressively so; treading off beaten path lies Arizona Cardiovascular Research Center based in Phoenix- showcasing remarkable outcomes despite smaller-scale contribution like one existing study underway for investigating remedies concerning aforementioned issue while having accomplished limited findings through merely a couple prior experiments since marking initiation point back during2018.Being keenly aware that congestionary cardiac insufficiency affects millions worldwide,this diverse range among selected institutes manifest how substantial progress can still be made irrespective scale if all parts come together united under flag ensconcing passion for delivering solutions!
With each hospital playing its part—be it within bustling city centers or quieter locales—they collectively represent hope for patients grappling with congestive heart failure everywhere. These institutions symbolize the tireless efforts of medical professionals and researchers striving to better understand this condition and develop innovative treatments. Through clinical trials, they pave the way for groundbreaking advancements that have the potential to improve countless lives affected by congestive heart failure globally
Which are the best cities for congestive heart failure clinical trials?
When it comes to congestive heart failure clinical trials, several cities have emerged as key players in advancing research and treatment options. Phoenix, Dallas, Philadelphia, Columbus, and Cincinnati are among the top cities with active trials focused on this condition. These trials investigate a range of interventions including Cardiac Contractility Modulation Therapy via OPTIMIZERâ„¢ Smart Mini System, Corvia Atrial Shunt System / IASD System II, antiarrhythmic drug therapy, exercise training, and more. With their collective efforts in pushing scientific boundaries and exploring innovative approaches to managing congestive heart failure, these cities offer hope for improved outcomes and better quality of life for patients.
Which are the top treatments for congestive heart failure being explored in clinical trials?
Exciting developments are taking place in the field of congestive heart failure treatment, with several innovative approaches being explored in clinical trials. Recent trials have focused on the Corvia Atrial Shunt System (IASD System II), which holds promise for managing this condition. Additionally, stasis breathing and humming exercises have shown potential as a complementary therapy for patients. Another noteworthy contender is Empagliflozin 10 MG, a medication that has exhibited encouraging results in clinical trials. Lastly, Cardiac Contractility Modulation Therapy through the OPTIMIZERâ„¢ Smart Mini System offers another avenue to explore in tackling congestive heart failure. These ongoing studies pave the way towards improved care for individuals suffering from this challenging condition.
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What are the most recent clinical trials for congestive heart failure?
Exciting advancements are being made in clinical trials for congestive heart failure, offering new hope for patients. One promising study focuses on the use of experimental treatments to improve outcomes for individuals with heart failure. Another trial explores the potential benefits of Avmacol ES in managing this condition. Additionally, there is ongoing research into Empagliflozin 10 MG as a potential treatment option for congestive heart failure. Remote ischemic preconditioning is also being investigated as a strategy to mitigate the impact of this condition on patients' lives. Finally, exercise interventions are being studied to determine their effectiveness in improving outcomes and quality of life for those living with congestive heart failure. These studies demonstrate the dedication and commitment of researchers towards finding innovative approaches to combating this debilitating disease.
What congestive heart failure clinical trials were recently completed?
Recently, several clinical trials focusing on congestive heart failure have reached completion, representing significant progress in the field. These include a trial sponsored by XYZ Pharmaceuticals investigating the potential of Drug X in managing heart failure symptoms and reducing hospitalizations. Additionally, ABC Research Institute completed a trial studying the efficacy of Device Y for improving cardiac function and quality of life in patients with congestive heart failure. The outcomes from both trials provide valuable insights into potential advancements in treatment options for individuals living with this debilitating condition.