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Trials for Indigestion Patients
Behavioural Intervention
Virtual Reality for Indigestion
This trial is testing whether using virtual reality can help people with functional dyspepsia feel better. Functional dyspepsia causes stomach pain and discomfort, and typical treatments don't always work. Virtual reality might help by distracting and relaxing patients, making their symptoms less noticeable.
Amino Acid
Glutamine for Indigestion
This trial is studying the effects of glutamine on patients with functional dyspepsia, a condition causing stomach discomfort. Glutamine is a protein building block that provides energy to gut cells and helps keep the gut lining strong. Researchers want to see if glutamine can improve symptoms and compare its safety and effectiveness. Glutamine has been studied for its potential benefits in reducing neurotoxicity in patients receiving chemotherapy, showing some degree of benefit in reducing symptoms like paresthesias and constipation.
Trials With No Placebo
Vagus Nerve Stimulator
Vagal Nerve Stimulation for Indigestion and Gastroparesis
This trial tests a treatment that sends mild electrical pulses to the outer ear to help people with stomach issues like functional dyspepsia and gastroparesis. The goal is to see if this can improve communication between the brain and stomach and reduce symptoms. Gastric electrical stimulation (GES) has been proposed as an effective treatment option for patients with gastroparesis that does not respond to other treatments.
Prokinetic Agent
Domperidone for Gastrointestinal Disorders
This trial studies how well domperidone works in treating patients aged 16 and older with gastrointestinal disorders. Domperidone helps the stomach move food more effectively by making its muscles contract. This can reduce symptoms like pain, bloating, nausea, and vomiting.
Non-invasive Brain Stimulation
Brain Stimulation for Gastrointestinal Disorders
This trial is testing a non-invasive brain stimulation technique called rTMS on healthy people and those with IBS or FD. The goal is to see if it can help regulate automatic body functions like digestion and heart rate by changing brain activity. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation technique that has been used to treat various neurological and psychiatric conditions, including major depression, migraine-associated headaches, and obsessive-compulsive disorder.
Frequently Asked Questions
Introduction to dyspepsia
What are the top hospitals conducting dyspepsia research?
When it comes to cutting-edge clinical trials focused on dyspepsia, several hospitals are at the forefront of research and innovation. Massachusetts General Hospital in Boston leads the way with two ongoing dyspepsia trials and a total of two completed studies dedicated to understanding this condition. Since recording their first trial in 2018, they have been committed to advancing knowledge and treatment options for patients experiencing dyspepsia.
Joining them is the Mayo Clinic in Florida, located in Jacksonville. This renowned institution has initiated one active clinical trial specifically targeting dyspepsia, with a single completed study as well. Interestingly, both the Mayo Clinic Florida branch and Torsak Vimoktayon hospital share similar numbers - each conducting one active trial and holding an equally impressive record of one all-time study conducted since their inaugural dyspepsia trials recorded in 2023.
Furthermore, Vanda Investigational Site based out of Rochester plays its part by actively participating in one current dyspepsia trial while having accomplished a previously held investigation prior to that year; tracing back only until 2022.
These institutions signify the dedication present within medical communities across different locations when it comes to studying and addressing gastrointestinal disorders such as dyspepsia. By continuously pushing boundaries through meticulous research efforts, these hospitals pave the way for advancements that will ultimately improve outcomes for individuals experiencing digestive issues.
Which are the best cities for dyspepsia clinical trials?
When it comes to dyspepsia clinical trials, several cities show promise as key locations for research. Jacksonville, Florida leads the way with 3 ongoing trials exploring treatments like Glutamine Group and Experimental interventions. Rochester, Minnesota follows closely behind with 2 active studies focusing on Tradipitant and Ondansetron 8mg among other options. Boston, Massachusetts also joins the ranks with 2 ongoing trials investigating Cognitive Behavioral Therapy and taVNS alongside other potential approaches. Additionally, Nashville in Tennessee offers a single active trial studying magnetogastrogram and Hamilton in Ontario explores treatment options such as gluten-free diets through one active trial. These cities serve as hubs for dyspepsia clinical research, providing opportunities for individuals seeking improved management of this condition.
Which are the top treatments for dyspepsia being explored in clinical trials?
The field of dyspepsia treatment is actively exploring several promising options in clinical trials. One such option is tradipitant, which currently has one active trial dedicated to dyspepsia and was first listed in 2022. Another avenue being explored is cognitive behavioral therapy, with one ongoing trial specific to dyspepsia and its first listing also occurring in 2022. Additionally, ondansetron 8mg shows potential as a treatment for dyspepsia, with one active trial and an all-time total of one dedicated study since it was initially listed in 2019. These innovative approaches offer hope for improving the management of this challenging condition.
What are the most recent clinical trials for dyspepsia?
Exciting advancements in dyspepsia research have led to several recent clinical trials that offer hope for improved treatment options. One notable trial involves the use of a glutamine group, which has shown promise in addressing dyspeptic symptoms. Additionally, tradipitant is being investigated as a potential therapeutic option for individuals with dyspepsia. Furthermore, ondansetron 8mg has been studied in relation to its efficacy in managing this condition. Although not as recent, the cross-over of ketotifen and domperidone trials have also contributed valuable insights into dyspepsia treatment approaches. With continued research efforts like these, we can anticipate significant strides towards better management of dyspeptic symptoms and improved quality of life for affected individuals.
What dyspepsia clinical trials were recently completed?
Recently completed clinical trials have contributed to advancing our understanding and treatment options for dyspepsia, a common digestive disorder. In October 2021, researchers at the University of California concluded a trial investigating the efficacy of a novel medication in relieving dyspeptic symptoms. Another significant study was completed in September 2021 by Johns Hopkins University, focusing on evaluating the benefits of a specialized diet intervention for individuals with dyspepsia. These recent trials provide valuable insights into potential therapeutic approaches and offer hope for improved management strategies for those affected by this condition.