Procedure
DBS Surgery for Hand Dystonia
This trial is testing a new procedure to treat focal hand dystonia, a condition that causes involuntary muscle movements. A device is placed in the chest and attached to wires in the brain, which stimulating the areas affected by dystonia can help to block nerve signals and improve symptoms.
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Trials for Essential Tremor Patients
Deep Learning Platform
DystoniaNet Diagnosis for Dystonia
This trial aims to validate a computer program called DystoniaNet that helps doctors diagnose dystonia more accurately. It targets patients with isolated dystonia who often experience delays in diagnosis. The program uses artificial intelligence to learn from data and identify signs of the disorder, improving diagnosis speed and accuracy.
Procedure
Deep Brain Stimulation for Spasmodic Dysphonia and Tremor
This trial studies how Deep Brain Stimulation (DBS) affects voice control in patients with dystonia and essential tremor. DBS sends electrical impulses to brain areas that manage movement, aiming to improve voice function in these patients. Deep Brain Stimulation (DBS) has been used to treat severe movement disorders, including Parkinson's disease, dystonia, and essential tremor.
Procedure
Deep Brain Stimulation for Parkinson's Disease
This trial is testing different types of deep brain stimulation to see which is most effective in treating Parkinson's, essential tremor, and multiple sclerosis. The results will help design more effective stimulation patterns and aid in understanding how DBS works.
Trials for ET Patients
Deep Learning Platform
DystoniaNet Diagnosis for Dystonia
This trial aims to validate a computer program called DystoniaNet that helps doctors diagnose dystonia more accurately. It targets patients with isolated dystonia who often experience delays in diagnosis. The program uses artificial intelligence to learn from data and identify signs of the disorder, improving diagnosis speed and accuracy.
Procedure
Deep Brain Stimulation for Spasmodic Dysphonia and Tremor
This trial studies how Deep Brain Stimulation (DBS) affects voice control in patients with dystonia and essential tremor. DBS sends electrical impulses to brain areas that manage movement, aiming to improve voice function in these patients. Deep Brain Stimulation (DBS) has been used to treat severe movement disorders, including Parkinson's disease, dystonia, and essential tremor.
Procedure
Deep Brain Stimulation for Parkinson's Disease
This trial is testing different types of deep brain stimulation to see which is most effective in treating Parkinson's, essential tremor, and multiple sclerosis. The results will help design more effective stimulation patterns and aid in understanding how DBS works.
Trials With No Placebo
Anticholinergic
Trihexyphenidyl for Cerebral Palsy
This trial is investigating how a medication called trihexyphenidyl affects children with dystonic cerebral palsy. Researchers want to learn how the body processes this medication in pediatric patients and if genetics play
Deep Learning Platform
DystoniaNet Diagnosis for Dystonia
This trial aims to validate a computer program called DystoniaNet that helps doctors diagnose dystonia more accurately. It targets patients with isolated dystonia who often experience delays in diagnosis. The program uses artificial intelligence to learn from data and identify signs of the disorder, improving diagnosis speed and accuracy.
Procedure
Deep Brain Stimulation for Spasmodic Dysphonia and Tremor
This trial studies how Deep Brain Stimulation (DBS) affects voice control in patients with dystonia and essential tremor. DBS sends electrical impulses to brain areas that manage movement, aiming to improve voice function in these patients. Deep Brain Stimulation (DBS) has been used to treat severe movement disorders, including Parkinson's disease, dystonia, and essential tremor.
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Frequently Asked Questions
Introduction to dystonia
What are the top hospitals conducting dystonia research?
In the realm of dystonia research, several distinguished hospitals are leading the way in advancing our understanding and treatment of this complex neurological condition. The Toronto Western Hospital in Canada stands out with three active clinical trials dedicated to dystonia, alongside seven completed trials since their first recorded investigation back in 2006. Across the border in Boston, two institutions are making significant strides as well. At the Massachusetts Eye and Ear Infirmary, researchers are currently conducting two ongoing dystonia trials while having achieved four previous studies since they embarked on their first trial in 2015. Meanwhile, at the renowned Massachusetts General Hospital, experts have initiated two active dystonia trials thus far but made a remarkable impact despite their relative newness by starting it's pioneering investigation merely last year during2020.
Further down south at the National Institutes of Health Clinical Center located in Bethesda has accomplished an impressive nine completed dystonia trials for innovation-oriented individuals running such experiments since all time from recording times back until2009.The London Health Sciences Centre may appear smaller-scale with only two current clinical tests ongoing and three previously held investigations; theirs can be traced back only a decade ago to2012.
Dystonia is a challenging condition characterized by involuntary muscle contractions that cause repetitive or twisting movements. It can affect various parts of the body and lead to significant pain and functional impairments for those living with it. These top hospitals' commitment to exploring novel approaches and therapies through clinical trials offers hope for improved outcomes and quality of life for individuals affected by dystonia worldwide. By delving into these innovative studies and expanding our knowledge base about this intricate disorder under different settings from across North America up until Europe; we advance towards more effective treatments while moving closer towards finding eventual cure
Which are the best cities for dystonia clinical trials?
In the realm of dystonia clinical trials, several cities emerge as prime locations for innovative research. Boston, Massachusetts takes the lead with 7 active trials investigating interventions like Deep Brain Stimulation and DystoniaNet-based diagnosis. Toronto, Ontario follows closely behind with 5 ongoing studies exploring treatments such as Transcranial ExAblate System and Active Low Intensity Transcranial Focused ultrasound. Gainesville, Florida also makes its mark with 3 active trials delving into approaches like Active biphasic pulse stimulation and progressive resistance exercise. Additionally, Bethesda, Maryland contributes to the field with 3 active trials focusing on treatment arm options and DBS surgery. While San Francisco, California boasts 2 active trials centered around Deep Brain Stimulation and targeted patients with Parkinson's disease GP Target. These cities serve as hotspots for individuals seeking participation in cutting-edge dystonia clinical trials that pave the way for advancements in care and improved quality of life.
Which are the top treatments for dystonia being explored in clinical trials?
Exploration of clinical trials for dystonia has identified two top treatments showing promise in recent research. DystoniaNet-based diagnosis of isolated dystonia is currently being tested in one active trial, marking its debut in the field with a single all-time dystonia trial since 2022. Deep Brain Stimulation, on the other hand, has gained attention with one ongoing trial and a total of six historic dystonia trials since its introduction back in 2011. These groundbreaking treatments offer hope to patients living with this challenging neurological disorder as researchers strive for advancements and improved outcomes.
What are the most recent clinical trials for dystonia?
Recent clinical trials offer promising prospects for individuals living with dystonia. One such trial focuses on Ingrezza, a medication undergoing Phase 4 testing, which has shown potential benefits in the management of dystonia symptoms. Additionally, botulinum toxin type A is being evaluated in Phase 2 and Phase 3 studies as a potential treatment option for this condition. Another trial investigates deutetrabenazine 6 MG and its efficacy in alleviating dystonia symptoms. Furthermore, deep brain stimulation (DBS) surgery is being explored as a possible intervention for managing dystonia. Although these trials have varying phases and availability dates ranging from as recent as October 2021 to earlier years like January 2018 or even January 2016, they collectively contribute to advancing our understanding of dystonia treatment options moving forward.
What dystonia clinical trials were recently completed?
Two noteworthy clinical trials investigating potential treatments for dystonia have recently concluded, signifying significant progress in the field. In July 2021, AEON Biopharma successfully completed a trial focusing on ABP-450. This was followed by another trial involving ABP-450 sponsored by AEON Biopharma in March 2021. These recent advancements bring hope to individuals living with dystonia and highlight the commitment of researchers towards finding effective therapies for this challenging condition.