Non-invasive Brain Stimulation
tDCS for Cognitive Impairment in Parkinson's Disease
This trial aims to use a novel personalized network analysis approach to elucidate the mechanisms of the effect of tDCS on cognitive dysfunction in non-demented PD patients.
Brain Stimulation
Brain Stimulation + Physical Therapy for Parkinson's Disease
This trial is testing whether a combination of transcranial direct current stimulation (tDCS) and transcranial ultrasound (TUS) can help improve postural instability in Parkinson's disease patients receiving physical therapy.
Bisphosphonate
Zoledronic Acid for Parkinson's Disease
This trial is testing whether a single infusion of zoledronic acid can help prevent fractures in people with Parkinson's disease or parkinsonism. A total of 3500 participants will be enrolled in the United States.
Popular Filters
Trials for Dementia Patients
Radiation
Radiosurgery for Essential Tremor
This trial is testing a non-surgical radiation treatment to help people with severe tremors from Essential Tremor or Parkinson's Disease who can't have traditional brain surgery. The treatment aims to reduce shaking by targeting specific brain areas with precise radiation. This minimally invasive alternative to traditional brain surgery is designed for treating tremors in conditions like Essential Tremor and Parkinson's Disease.
Behavioural Intervention
Electrical Brain Stimulation for Parkinson's Disease
This trial is testing whether electrical stimulation of the brain can help reduce cognitive fatigue and improve cognitive function in patients with Parkinson's disease and mild cognitive impairment.
Trials for PD Patients
Radiation
Radiosurgery for Essential Tremor
This trial is testing a non-surgical radiation treatment to help people with severe tremors from Essential Tremor or Parkinson's Disease who can't have traditional brain surgery. The treatment aims to reduce shaking by targeting specific brain areas with precise radiation. This minimally invasive alternative to traditional brain surgery is designed for treating tremors in conditions like Essential Tremor and Parkinson's Disease.
Behavioural Intervention
Electrical Brain Stimulation for Parkinson's Disease
This trial is testing whether electrical stimulation of the brain can help reduce cognitive fatigue and improve cognitive function in patients with Parkinson's disease and mild cognitive impairment.
Trials With No Placebo
Radiation
Radiosurgery for Essential Tremor
This trial is testing a non-surgical radiation treatment to help people with severe tremors from Essential Tremor or Parkinson's Disease who can't have traditional brain surgery. The treatment aims to reduce shaking by targeting specific brain areas with precise radiation. This minimally invasive alternative to traditional brain surgery is designed for treating tremors in conditions like Essential Tremor and Parkinson's Disease.
Procedure
Deep Brain Stimulation for Parkinson's Disease
This trial is testing different types of deep brain stimulation to see which is most effective in treating Parkinson's, essential tremor, and multiple sclerosis. The results will help design more effective stimulation patterns and aid in understanding how DBS works.
Cannabinoid
Medical Cannabis for Chronic Pain
This trial will investigate if medical cannabis can effectively reduce pain and improve quality of life for patients with chronic conditions. The study will gather data through an online questionnaire about patients' use of cannabis and its effects. Medical cannabis interacts with the body's natural system to help manage pain and other symptoms. Medical cannabis has been increasingly studied and used as an alternative treatment for managing chronic pain, with numerous studies supporting its potential benefits.
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Frequently Asked Questions
Introduction to parkinson's disease
What are the top hospitals conducting parkinson's disease research?
Cutting-edge research in the field of Parkinson's disease is being conducted at several leading hospitals across the United States. Located in vibrant Nashville, Vanderbilt University Medical Center is actively engaged in five clinical trials focused on this debilitating condition. With a commendable history of 26 past trials, dating back to their first recorded study in 2007, Vanderbilt remains committed to advancing our understanding and treatment options for Parkinson's disease. Heading further south to Gainesville, Florida, we find the University of Florida making significant strides as well. This esteemed institution currently has four ongoing trials dedicated to exploring innovative approaches for managing Parkinson's disease. Since initiating their first trial back in 2004, they have contributed an impressive total of 36 studies to the scientific community.
In Birmingham, Alabama, another powerhouse emerges with the University of Alabama at Birmingham dedicating its efforts towards four active Parkinson's disease trials. Boasting a similar track record as their counterparts in Gainesville with a cumulative total of 36 completed studies since starting their initial investigation also in 2004; these researchers are striving tirelessly to improve outcomes and quality of life for those affected by this neurodegenerative disorder.
Moving westward toward Stanford University situated within California’s iconic Silicon Valley region we encounter yet another prestigious institution dedicated to tackling Parkinson's head-on. With four active clinical trials underway and ten past investigations under their belt since recording their first trial occurrence during early months .of year twenty-eighth , Stanford continues pushing boundaries through cutting-edge research.
Finally reaching Cleveland Clinic located conveniently amidst bustling Cleveland cityscape; Another key player enters stage possessing remarkable expertise regarding parkinsons while conducting current quartet tests along with thirty-eight previous endeavors all combined together from it’s onset time when they initiated inaugural evaluation revolving around parkinsonism was done so closely after start-of-previous-decade i.e just upon turn-into two-thousand-and-six AD
These top hospitals epitomize dedication and collaboration, bringing together the brightest minds in Parkinson's disease research. By harnessing their collective expertise and resources, they continue to make significant strides that hold promise for improving the lives of individuals affected by this challenging condition.
Which are the best cities for parkinson's disease clinical trials?
When it comes to [Parkinson's disease](https://www.withpower.com/clinical-trials/parkinson's-disease) clinical trials, several cities have emerged as prominent locations for research. New york, with its 13 active trials, focuses on studying interventions such as LY3884961, Zoledronic acid (ZA), and ExAblate Pallidotomy. Philadelphia also plays a significant role in advancing Parkinson's research with 11 ongoing studies exploring treatments like Gameficiation and Waitlist Couple Pairs Parkinson's Group. Similarly, Boston contributes to the field with 11 active trials investigating interventions such as mHealth delivered exercise programs and Digital music therapy. Chicago follows closely behind with 10 ongoing trials examining treatments like Sulvecaltamide and Treadmill walking. Lastly, Miami conducts nine active trials that explore various interventions alongside Zoledronic acid (ZA). These cities serve as vital hubs for individuals seeking participation in cutting-edge clinical trials focused on improving treatment options for Parkinson's disease patients.
Which are the top treatments for parkinson's disease being explored in clinical trials?
Exciting developments are unfolding in the realm of [Parkinson's disease](https://www.withpower.com/clinical-trials/parkinson's-disease) research, as clinical trials explore innovative treatments. One standout contender is Felix, a promising therapy currently undergoing one active trial for Parkinson's. Introduced in 2023, it has already made significant strides with its potential to offer relief and improve patient outcomes. Another noteworthy approach is Inspiratory Muscle Training, which focuses on strengthening respiratory muscles and has shown promise in alleviating symptoms associated with Parkinson's disease. This intervention also boasts one ongoing trial since its first listing in 2018. Lastly, advanced treadmill walking emerges as a novel treatment option worth investigating further—its single active trial aims to evaluate its effectiveness for individuals living with this neurodegenerative disorder after being introduced in 2022. These groundbreaking therapies inject hope into the lives of those affected by Parkinson's while pushing boundaries in the pursuit of improved quality of life.
What are the most recent clinical trials for parkinson's disease?
Exciting advancements are being made in the field of [Parkinson's disease](https://www.withpower.com/clinical-trials/parkinson's-disease) research, with recent clinical trials offering new possibilities for treatment. One such trial focuses on eiDBS suppression, a Phase 4 study that aims to evaluate the effectiveness of deep brain stimulation in managing Parkinson's symptoms. Another trial, known as Waitlist Couple Pairs Parkinson's Group, is currently in Phase 2 and explores the benefits of group therapy for couples living with Parkinson's disease. Additionally, i-BiSSkApp Group is a Phase 1 trial investigating how an innovative app-based intervention can improve quality of life for individuals affected by this neurodegenerative disorder. Furthermore, Delayed Start - PD provides insight into potential therapeutic strategies by examining the effects of delayed initiation of treatment on disease progression. Lastly, IkT-148009 enters Phase 2 testing its efficacy as a targeted therapy specifically designed for patients with Parkinson's disease. These ongoing trials hold immense promise and provide hope for improved management and ultimately better outcomes for those living with this condition.
What parkinson's disease clinical trials were recently completed?
Recent clinical trials in the field of [Parkinson's disease](https://www.withpower.com/clinical-trials/parkinson's-disease) have showcased remarkable advancements. In July 2022, Five Eleven Pharma, Inc. successfully completed a trial evaluating the potential of [18F]P17-059 therapy. Another notable achievement came in January 2022 with AbbVie's completion of their ABBV-951 trial for Parkinson's disease. BioVie Inc.'s NE3107 trial also concluded in January 2022, offering further insights into potential treatment options. These recent developments join earlier milestones such as The Michael J. Fox Foundation for Parkinson's Research completing its [18F] PI-2620 trial in August 2021 and Eisai Inc.'s successful E2027 study wrapped up in February 2021, highlighting ongoing efforts to combat this complex neurological disorder.