Diagnostic Imaging for Pheochromocytoma
This trial is testing better methods to detect, locate, and treat pheochromocytomas. These are tumors that usually form in the adrenal glands and can cause high blood pressure. They can be hard to detect with current methods and can lead to severe medical consequences if left undetected.
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Trials for Adrenal Gland Pheochromocytoma Patients
Behavioral Nudge for Genetic Predisposition
This trial aims to find new ways to deliver genetic testing results that can change medical management beyond traditional genetic counseling visits. The study will use non-geneticist clinicians and patient nudges in a randomized clinical
[18F]FluorThanatrace PET/CT Imaging for Pheochromocytoma and Paraganglioma
This trial will investigate a PET/CT imaging scan to assess PARP-1 expression in pheochromocytoma/paraganglioma patients before surgery/systemic therapy. It won't influence treatment decisions.
CAR T-cell Therapy
IL13Ralpha2 CAR T Cells for Advanced Skin Cancer
This trial tests the safety and best dose of modified immune cells for patients with advanced melanoma or other cancers that have spread. The treatment uses the patient's own T cells, which are changed in a lab to better attack cancer cells. The goal is to see if these modified cells can safely and effectively fight the cancer.
Trials for PCC Patients
Behavioral Nudge for Genetic Predisposition
This trial aims to find new ways to deliver genetic testing results that can change medical management beyond traditional genetic counseling visits. The study will use non-geneticist clinicians and patient nudges in a randomized clinical
[18F]FluorThanatrace PET/CT Imaging for Pheochromocytoma and Paraganglioma
This trial will investigate a PET/CT imaging scan to assess PARP-1 expression in pheochromocytoma/paraganglioma patients before surgery/systemic therapy. It won't influence treatment decisions.
CAR T-cell Therapy
IL13Ralpha2 CAR T Cells for Advanced Skin Cancer
This trial tests the safety and best dose of modified immune cells for patients with advanced melanoma or other cancers that have spread. The treatment uses the patient's own T cells, which are changed in a lab to better attack cancer cells. The goal is to see if these modified cells can safely and effectively fight the cancer.
Trials With No Placebo
Behavioral Nudge for Genetic Predisposition
This trial aims to find new ways to deliver genetic testing results that can change medical management beyond traditional genetic counseling visits. The study will use non-geneticist clinicians and patient nudges in a randomized clinical
[18F]FluorThanatrace PET/CT Imaging for Pheochromocytoma and Paraganglioma
This trial will investigate a PET/CT imaging scan to assess PARP-1 expression in pheochromocytoma/paraganglioma patients before surgery/systemic therapy. It won't influence treatment decisions.
CAR T-cell Therapy
IL13Ralpha2 CAR T Cells for Advanced Skin Cancer
This trial tests the safety and best dose of modified immune cells for patients with advanced melanoma or other cancers that have spread. The treatment uses the patient's own T cells, which are changed in a lab to better attack cancer cells. The goal is to see if these modified cells can safely and effectively fight the cancer.
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Frequently Asked Questions
Introduction to pheochromocytoma
What are the top hospitals conducting pheochromocytoma research?
In the realm of clinical trials for pheochromocytoma, several prominent hospitals are working tirelessly to advance our understanding and treatment options for this rare adrenal gland tumor. At the National Institutes of Health Clinical Center in Bethesda, groundbreaking research is underway with four active trials focused on pheochromocytoma. Over the years, they have contributed to a total of seven such trials since recording their first endeavor in 2000. Meanwhile, Memorial Sloan Kettering Cancer Center in New york has joined the mission by currently conducting three active pheochromocytoma trials. Although their overall count may seem modest at three all-time trials since 2006, each study represents an important step forward.
M D Anderson Cancer Center leads from Houston as another powerhouse dedicated to battling this challenging condition. With three ongoing pheochromocytoma studies and a cumulative tally of seven completed trials since embarking on their inaugural investigation in 2011, they continue to make significant strides towards improving patient outcomes. Not far behind is the University of Iowa located in Iowa City, where two current pheochromocytoma clinical trials are making notable contributions alongside their previous three conducted studies dating back to 2009.
It's worth noting that M D Anderson Cancer Center's second location also plays an integral role within this field; together with its main campus it shares two ongoing pheochromocytoma investigations while having carried out a combined total of three over time starting from around twelve years ago(around same time).
These remarkable institutions across various locations exemplify the unwavering commitment that medical professionals have towards finding better solutions for patients affected by rare conditions like pheochromocytoma. Every trial conducted brings us closer to unlocking new treatments and ultimately offers hope for those facing these daunting health challenges
Which are the best cities for pheochromocytoma clinical trials?
When it comes to pheochromocytoma clinical trials, several cities stand out as hubs for research and innovation. New york City leads the pack with 12 active trials investigating treatments such as Tipifarnib, Axitinib, and Lanreotide. Los Angeles follows closely behind with 10 ongoing studies focused on Nivolumab, Tipifarnib, and Doxazosin. Anchorage in Alaska also shows promise with 9 active trials exploring options like Nivolumab and Tipifarnib. Additionally, Houston in Texas has 7 active trials studying Lutetium [177Lu] oxodotreotide/dotatate, EO2401, Belzutifan among others. Lastly, Bethesda in Maryland contributes to the field with 6 ongoing trials investigating ([18F]-6F-DA), Talazoparib, Temozolomide along with other potential breakthroughs. These cities offer individuals affected by pheochromocytoma access to cutting-edge clinical trials that pave the way for advancements in care and bring hope for better treatment outcomes.
Which are the top treatments for pheochromocytoma being explored in clinical trials?
Exciting developments are underway in the realm of pheochromocytoma treatment, with several promising options being explored in clinical trials. One highly anticipated contender is Lutetium [177Lu] oxodotreotide/dotatate, currently involved in one active trial and representing a breakthrough since its first listing in 2022. Another potential game-changer is EO2401, also undergoing investigation in one ongoing trial after making its debut on the scene in 2020. Rounding out this trio of top contenders is Axitinib, showcasing its potential through one active trial following its introduction to the field back in 2019. As researchers delve into these treatments further, hope continues to grow for improved outcomes and enhanced quality of life for individuals battling pheochromocytoma.
What are the most recent clinical trials for pheochromocytoma?
Exciting advancements in clinical trials offer hope for individuals with pheochromocytoma, a rare neuroendocrine tumor. Among the most recent studies is a trial investigating dose escalation as a potential treatment strategy. This trial encompasses both Phase 1 and Phase 2, showcasing its comprehensive approach to evaluating safety and efficacy. Another notable study explores the use of Lutetium [177Lu] oxodotreotide/dotatate for pheochromocytoma patients, aiming to harness targeted therapy to combat this challenging condition. Furthermore, Talazoparib presents promise as an innovative treatment option through its involvement in a Phase 2 trial. These studies highlight the ongoing commitment towards finding effective treatments and improving outcomes for those affected by pheochromocytoma
What pheochromocytoma clinical trials were recently completed?
Mayo Clinic recently completed a notable clinical trial in May 2017 investigating the efficacy of Lenvatinib for pheochromocytoma. This trial marks an important step in advancing our understanding and treatment options for this rare neuroendocrine tumor.