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What is Elixophyllin
TheophyllineThe Generic name of this drug
Treatment SummaryTheophylline is a medication derived from tea that works as a diuretic, muscle relaxant, and bronchodilator. It also stimulates the heart and central nervous system. Theophylline works by blocking certain enzymes and activating histone deacetylase. It is mainly used to treat asthma, breathing problems, and chronic obstructive pulmonary disease (COPD), and is sold under the brand names Uniphyl and Theochron.
Elixophyllinis the brand name
Elixophyllin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Elixophyllin
Theophylline
1979
114
Approved as Treatment by the FDA
Theophylline, commonly known as Elixophyllin, is approved by the FDA for 4 uses like Asthma and Lung Disorder .Asthma
Lung Disorder
Bronchoconstriction
Chronic Bronchitis
Effectiveness
How Elixophyllin Affects PatientsTheophylline is a medication used to treat asthma and bronchial spasms, and is chemically similar to caffeine and theobromine. It works by relaxing the airways (to reduce bronchospasms) and by reducing sensitivity of the airways to triggers.
How Elixophyllin works in the bodyTheophylline works by relaxing the muscles of the airways and reducing their sensitivity to allergens and other irritants. It does this by blocking enzymes that break down molecules responsible for muscle contraction, as well as blocking a receptor that can cause airway constriction. In addition, it can reduce inflammation by preventing proteins involved in the inflammatory process from being made.
When to interrupt dosage
The prescribed dosage of Elixophyllin is contingent upon the identified condition, such as Bronchodilation, Bronchoconstriction and Chronic Obstructive Pulmonary Disease (COPD). The dose is subject to the technique of administration as specified in the table below.Condition
Dosage
Administration
Acute Bronchitis
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Bronchospasm
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Asthma
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Emphysema
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Bronchoconstriction
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Chronic Obstructive Pulmonary Disease
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Chronic Bronchitis
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Lung Disorder
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Bronchodilation
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Chronic bronchial inflammation
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Airway secretion clearance therapy
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Warnings
There are 20 known major drug interactions with Elixophyllin.Common Elixophyllin Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Theophylline.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Theophylline.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Theophylline.
Bendamustine
Major
The metabolism of Bendamustine can be decreased when combined with Theophylline.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Theophylline.
Elixophyllin Toxicity & Overdose RiskSigns of an overdose on this drug include seizures, abnormal heart rhythms, and stomach issues.
Elixophyllin Novel Uses: Which Conditions Have a Clinical Trial Featuring Elixophyllin?
280 clinical trials are presently in progress to assess the potential of Elixophyllin in providing Bronchodilation, ameliorating Chronic Bronchitis and managing Asthma.Condition
Clinical Trials
Trial Phases
Asthma
156 Actively Recruiting
Phase 1, Phase 2, Phase 4, Not Applicable, Early Phase 1, Phase 3
Bronchodilation
0 Actively Recruiting
Acute Bronchitis
12 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2
Bronchospasm
0 Actively Recruiting
Chronic bronchial inflammation
0 Actively Recruiting
Airway secretion clearance therapy
0 Actively Recruiting
Emphysema
12 Actively Recruiting
Phase 3, Phase 4, Not Applicable, Phase 1, Phase 2
Bronchoconstriction
0 Actively Recruiting
Chronic Obstructive Pulmonary Disease
99 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4
Chronic Bronchitis
4 Actively Recruiting
Not Applicable, Phase 4
Lung Disorder
9 Actively Recruiting
Not Applicable, Phase 1, Phase 2
Patient Q&A Section about elixophyllin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Elixophyllin used for?
"If you want to avoid wheezing and shortness of breath, you need to use this medication regularly. It's a type of drug called a xanthine, which relaxes the muscles around your airways so you can breathe more easily. Using it also reduces the lungs' reaction to irritants."
Answered by AI
What are the side effects adverse reactions and drug interactions related to Elixophyllin?
"The following list outlines some of the side effects that have been associated with theophylline use:
-Nausea -Vomiting -Headache -Insomnia
These side effects are generally mild when peak serum theophylline concentrations are <20 mcg/mL."
Answered by AI
What drugs contain theophylline?
"The medication elixophyllin is used to treat asthma and other respiratory conditions. It is available in oral and inhalation forms. Other medications in this class include Norphyl, Phyllocontin, Quibron-T, Quibron-TSR, Theo-24, TheoCap, and Theochron."
Answered by AI