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What is Hydroflumethiazide
HydroflumethiazideThe Generic name of this drug
Treatment SummaryA thiazide diuretic is a medication used to reduce fluid retention in the body. It works similar to hydrochlorothiazide and is used to treat a variety of conditions.
Saluronis the brand name
Hydroflumethiazide Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Saluron
Hydroflumethiazide
2006
1
Effectiveness
How Hydroflumethiazide Affects PatientsHydroflumethiazide is a pill used to lower high blood pressure and reduce swelling. High blood pressure can strain the heart and arteries, leading to health issues like stroke, heart failure, and kidney failure. Hydroflumethiazide helps to reduce these risks by causing the body to lose excess water and salt through urination. It also works by relaxing the blood vessels, allowing the heart to work more efficiently. Studies have shown that Hydroflumethiazide can help prevent health problems associated with high blood pressure, although the exact reason why is not known.
How Hydroflumethiazide works in the bodyHydroflumethiazide is a type of medication that helps the body get rid of extra water. It does this by blocking a specific protein in the kidneys called the sodium-chloride symporter. This protein usually takes sodium and chloride from the urine and puts it back into the body. By blocking this protein, Hydroflumethiazide reduces the amount of sodium and chloride in the body, which reduces the amount of water the body absorbs. This helps the body get rid of extra water.
When to interrupt dosage
The prescribed dosage of Hydroflumethiazide is contingent upon the identified disorder, including Oestrogen therapy, Renal Dysfunction and Swelling. The quantity of dosage is dependent on the method of administration laid out in the table underneath.Condition
Dosage
Administration
Nephrotic Syndrome
50.0 mg,
Oral, Tablet, , Tablet - Oral
Swollen feet or ankles
50.0 mg,
Oral, Tablet, , Tablet - Oral
Glomerulonephritis
50.0 mg,
Oral, Tablet, , Tablet - Oral
Kidney Diseases
50.0 mg,
Oral, Tablet, , Tablet - Oral
Therapeutic procedure
50.0 mg,
Oral, Tablet, , Tablet - Oral
Chronic Kidney Disease
50.0 mg,
Oral, Tablet, , Tablet - Oral
Congestive Heart Failure
50.0 mg,
Oral, Tablet, , Tablet - Oral
Hypertensive disease
50.0 mg,
Oral, Tablet, , Tablet - Oral
Cirrhosis
50.0 mg,
Oral, Tablet, , Tablet - Oral
Oestrogen therapy
50.0 mg,
Oral, Tablet, , Tablet - Oral
Warnings
Hydroflumethiazide ContraindicationsCondition
Risk Level
Notes
Anuria
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Hydroflumethiazide may interact with Pulse Frequency
Common Hydroflumethiazide Drug Interactions
Drug Name
Risk Level
Description
Amifostine
Major
Hydroflumethiazide may increase the hypotensive activities of Amifostine.
Cyclopentamine
Major
The risk or severity of adverse effects can be increased when Hydroflumethiazide is combined with Cyclopentamine.
Dofetilide
Major
The risk or severity of QTc prolongation can be increased when Hydroflumethiazide is combined with Dofetilide.
Lithium carbonate
Major
Hydroflumethiazide may decrease the excretion rate of Lithium carbonate which could result in a higher serum level.
Lithium citrate
Major
Hydroflumethiazide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Hydroflumethiazide Toxicity & Overdose RiskAn overdose of this drug can cause increased urination, fatigue, and eventually, a coma. There may be minimal effects on the heart and lungs, and minimal changes in the body's electrolytes or dehydration.
Hydroflumethiazide Novel Uses: Which Conditions Have a Clinical Trial Featuring Hydroflumethiazide?
At present, 143 active clinical trials are being conducted to assess the potential of Hydroflumethiazide to ameliorate Cirrhosis, Glomerulonephritis and therapeutic interventions.Condition
Clinical Trials
Trial Phases
Glomerulonephritis
0 Actively Recruiting
Chronic Kidney Disease
1 Actively Recruiting
Phase 3
Kidney Diseases
0 Actively Recruiting
Oestrogen therapy
0 Actively Recruiting
Swollen feet or ankles
6 Actively Recruiting
Phase 2, Not Applicable
Hypertensive disease
22 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Nephrotic Syndrome
11 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3
Congestive Heart Failure
15 Actively Recruiting
Not Applicable, Phase 1, Phase 2
Therapeutic procedure
0 Actively Recruiting
Cirrhosis
51 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 4, Phase 3, Early Phase 1
Patient Q&A Section about hydroflumethiazide
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Diucardin used for?
"Ducardin is a drug used to help manage hypertension, either on its own or with other drugs, in more severe cases."
Answered by AI
What type of diuretic is Diuril?
"Diuril is a diuretic drug used to relieve fluid retention and edema, as well as hypertension. It may be used alone or in conjunction with other medications."
Answered by AI
Which heterocyclic ring is present in furosemide?
"Furosemide is a drug used to treat congestive heart failure. It is a diuretic, which means it helps the body get rid of excess water. It is made up of a group of chemicals called chlorobenzoic acid."
Answered by AI
What class is Bendroflumethiazide?
"Bendroflumethiazide is a type of thiazide diuretic, which is a medication that helps increase the amount of urine passed from the kidneys. Diuretics are often used to treat high blood pressure (hypertension)."
Answered by AI