Ibuprofen

Insomnia, Catarrh, Chronic Pain + 33 more
Treatment
13 FDA approvals
20 Active Studies for Ibuprofen

What is Ibuprofen

IbuprofenThe Generic name of this drug
Treatment SummaryIbuprofen is a medication used to reduce inflammation and pain. It is a type of non-steroidal anti-inflammatory drug (NSAID) and was first developed in 1960 as an alternative to aspirin. Ibuprofen was patented in 1961 and was first released to treat rheumatoid arthritis in the UK in 1969 and the US in 1974. It is available over-the-counter in the form of a racemic mixture, meaning it contains both the R- and S-enantiomers. The S-enantiomer is believed to be more effective than the R-enantiomer in treating pain and inflammation
Motrinis the brand name
Ibuprofen Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Motrin
Ibuprofen
1974
2460

Approved as Treatment by the FDA

Ibuprofen, also called Motrin, is approved by the FDA for 13 uses including Acute Pain and Dysmenorrhea .
Acute Pain
Used to treat Pain, Acute in combination with Oxycodone
Dysmenorrhea
Gastric Ulcer
Used to treat Gastric Ulcer in combination with Famotidine
Mild pain
Rheumatoid Arthritis
Used to treat Rheumatoid Arthritis in combination with Famotidine
Stomach Ulcer
Used to treat Gastric Ulcer in combination with Famotidine
Pain, Acute
Used to treat Pain, Acute in combination with Oxycodone
Osteoarthritis (OA)
Used to treat Osteoarthritis (OA) in combination with Famotidine
Migraine
Osteoarthritis
Used to treat Osteoarthritis (OA) in combination with Famotidine
Fever
Headache
Menstrual Distress (Dysmenorrhea)

Effectiveness

How Ibuprofen Affects PatientsIbuprofen is used to manage pain, fever, and inflammation. It works by blocking the production of prostanoids, which are substances involved in inflammation. Ibuprofen can also help with dental procedures, menstrual pain, and migraines. It may also reduce neurodegeneration and help with Parkinson's Disease and breast cancer.
How Ibuprofen works in the bodyIbuprofen works by blocking an enzyme called cyclooxygenase. This enzyme helps create substances called prostaglandins, which cause pain and fever. Ibuprofen stops the production of prostaglandins, which reduces inflammation, pain, fever, and swelling. However, blocking this enzyme can also lead to side effects like stomach ulcers.

When to interrupt dosage

The recommended dose of Ibuprofen is reliant upon the identified condition, including smooth muscle relaxation prior to radiological procedures, Catarrh and Pain relief. The quantity of dosage differs, according to the technique of delivery (e.g. Kit - Oral; Topical or Tablet) featured in the table below.
Condition
Dosage
Administration
Analgesics
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Migraine Disorders
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Muscle Spasticity
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Opioids
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Stomach Ulcer
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Nasal Congestion
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Arthritis, Gouty
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Spasm
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Dysmenorrhea
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Premature Birth
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Juvenile arthritis
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Muscle Relaxation
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Acute Pain
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Mild pain
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Primary Dysmenorrhoea
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Pain
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Influenza
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Chronic Pain
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Migraine
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops
Pain
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Tablet, coated - Oral, Suspension, Capsule, liquid filled - Oral, Capsule, liquid filled, Tablet, chewable - Oral, Tablet, chewable, Tablet, sugar coated, Tablet, sugar coated - Oral, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Suspension - Oral, Kit, Solution, Solution - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution, Injection, solution - Intravenous, Kit - Oral, Capsule, coated, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Topical, Cream, Cream - Topical, Kit - Topical, Solution - Topical, Gel - Topical, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Gel, Solution / drops

Warnings

Ibuprofen Contraindications
Condition
Risk Level
Notes
Coronary Artery Bypass Grafting
Do Not Combine
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Ibuprofen.
Common Ibuprofen Drug Interactions
Drug Name
Risk Level
Description
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Ibuprofen.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Ibuprofen.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Ibuprofen.
Erlotinib
Major
The metabolism of Erlotinib can be decreased when combined with Ibuprofen.
Fluorouracil
Major
The metabolism of Fluorouracil can be decreased when combined with Ibuprofen.
Ibuprofen Toxicity & Overdose RiskConsuming more than 99mg/kg of ibuprofen can lead to abdominal pain, nausea, vomiting, fatigue, dizziness, vertigo, drowsiness, insomnia, headache, fainting, ringing in the ears, depression of the central nervous system, seizures, and difficulty breathing. In very rare cases, it can also cause metabolic acidosis, abnormal liver function, high potassium levels, kidney failure, and coma. The reported lethal dose of ibuprofen is 636mg/kg in rats, 740mg/kg in mice, and 495mg/kg in guinea pigs.

Ibuprofen Novel Uses: Which Conditions Have a Clinical Trial Featuring Ibuprofen?

At present, there are 531 active trials examining the potential of Ibuprofen in managing Rheumatoid Arthritis, Chronic Pain and Migraine Symptoms.
Condition
Clinical Trials
Trial Phases
Premature Birth
24 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1
Rheumatoid Arthritis
55 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1
Influenza
0 Actively Recruiting
Pain
0 Actively Recruiting
Aquaporin 2
3 Actively Recruiting
Phase 3, Not Applicable, Phase 2
Chronic Pain
129 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 3, Early Phase 1, Phase 1
Migraine
51 Actively Recruiting
Phase 4, Not Applicable, Phase 1, Phase 3, Phase 2, Early Phase 1
Muscle Relaxation
0 Actively Recruiting
Juvenile arthritis
8 Actively Recruiting
Phase 2, Not Applicable, Phase 3
Migraine
13 Actively Recruiting
Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4
Acute Pain
1 Actively Recruiting
Not Applicable
Primary Dysmenorrhoea
1 Actively Recruiting
Not Applicable
Nasal Congestion
0 Actively Recruiting
Catarrh
0 Actively Recruiting
Pericarditis
1 Actively Recruiting
Phase 2, Phase 3
Arthritis, Gouty
0 Actively Recruiting
Insomnia
0 Actively Recruiting
Pain
0 Actively Recruiting
Cystic Fibrosis
0 Actively Recruiting
Pain
0 Actively Recruiting

Patient Q&A Section about ibuprofen

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who should not take ibuprofen?

"If you have severe heart failure, severe kidney failure or severe liver failure, are trying to get pregnant, have high blood pressure that's not under control, have heart disease or mild to moderate heart failure, or have ever had a stroke, you may not be able to use Invokana."

Answered by AI

What is ibuprofen used for?

"Ibuprofen can be bought without a prescription and is a type of painkiller known as an NSAID. It can be used to relieve mild to moderate pain, such as toothache, migraine, and period pain."

Answered by AI

How is ibuprofen harmful?

"NSAIDs may cause ulcers, bleeding, or holes in the stomach or intestine, which can develop at any time during treatment and may happen without warning symptoms. This can lead to death."

Answered by AI

What is better Tylenol or ibuprofen?

"Acetaminophen is most effective for fever, aches, and pains, but is less effective for pain caused by inflammation. Ibuprofen is more effective for pain caused by inflammation, such as menstrual cramps and arthritis."

Answered by AI

Clinical Trials for Ibuprofen

Image of McGill University Health Centre in Montreal, Canada.

Dexmedetomidine for Pain Relief

18 - 75
All Sexes
Montreal, Canada
This study will compare three different doses of perineural dexmedetomidine 0.67 mcg/kg, 1 mcg/kg, and 1.33 mcg/kg as adjuvants to local anesthetics for ultrasound-guided infraclavicular brachial plexus blocks (ICBs). Our research hypothesis is that 1.33 mcg/kg will provide a 15%-longer duration than 1mcg/kg, which in turn will provide a 15%-longer duration than 0.67 mcg/kg. Since analgesic duration and sensory duration can be influenced by intake of pain medications and surgical trauma to small cutaneous nerves, respectively, we will select motor block duration as the main outcome to better target the action of dexmedetomidine on the brachial plexus.
Phase 2
Waitlist Available
McGill University Health CentreJulián Aliste, MD
Have you considered Ibuprofen clinical trials? We made a collection of clinical trials featuring Ibuprofen, we think they might fit your search criteria.Go to Trials
Image of California Clinical Trials Medical Group in Glendale, United States.

NTR-1011 for Lupus and Rheumatoid Arthritis

18 - 75
All Sexes
Glendale, CA
This phase 1a and 1b study is designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary efficacy of NTR-1011 in healthy adults and in adult patients with systemic lupus erythematosus and rheumatoid arthritis. The main goals of this study are to determine the safety profile of NTR-1011 across subcutaneous and intravenous dose levels, understand how the drug behaves in the body, characterize its biological activity through relevant pharmacodynamic markers, assess the potential for immune responses to treatment, and explore early signals of clinical benefit in autoimmune disease settings. This is a randomized, double blind, placebo controlled study that begins with a single ascending dose evaluation in healthy volunteers followed by a multiple dose assessment in patients. The design is intended to define the highest safe and well tolerated dose, establish a robust PK and PD baseline, and generate initial patient level evidence to support dose selection and advancement into subsequent clinical development.
Phase 1
Recruiting
California Clinical Trials Medical GroupHakop Gevorkyan, MDNeutrolis
Have you considered Ibuprofen clinical trials? We made a collection of clinical trials featuring Ibuprofen, we think they might fit your search criteria.Go to Trials
Image of Johns Hopkins Medicine in Baltimore, United States.

Embolization for Migraine

18 - 80
All Sexes
Baltimore, MD
This study is to test the safety and feasibility of a procedure called embolization of the middle meningeal arteries (MMA), using a product called Onyx. Embolization creates a plug in the arteries. MMA embolization with Onyx is not approved for use in patients with migraines, but is currently used in patients with subdural hematomas. The FDA is allowing the use of Onyx in this study. It is thought that by using Onyx to block the middle meningeal arteries, the amount of migraine-causing substances which are released into the brain's bloodstream will be reduced. The company that manufactures Onyx, Medtronic, is providing the supplies for this study. Participants will be in the study for about 8 months after enrolling, including 6 months of follow up after the procedure. The participants will be asked to complete a daily headache diary and continue the participant's regular migraine medications. Participants will also have several clinic visits and be asked to provide blood samples for research.
Waitlist Available
Has No Placebo
Johns Hopkins MedicineRisheng Xu, MD, PhDMedtronic
Image of Baylor College of Medicine/Texas Children's Hospital in Austin, United States.

Guided Imagery Therapy for Abdominal Pain

7 - 12
All Sexes
Austin, TX
Chronic abdominal pain is common among children, and the majority of cases are attributed to functional abdominal pain disorders. One approach to treating these disorders is by using psychological therapies. This clinical trial aims to see how well pre-recorded guided imagery therapy sessions help children's abdominal pain when delivered via a mobile application (app) on a smartphone or tablet. Participants will complete a baseline abdominal pain and stooling diary to determine eligibility, as well as other surveys. Eligible participants will be given access to the guided imagery therapy mobile application. This intervention asks participants to listen to a 10- to 15-minute GIT session 5 out of 7 days per week for 8 weeks, in addition to their usual care for their abdominal pain. Then, participants will complete another abdominal pain and stooling diary, along with other psychometric surveys, at the end of this intervention period. Participants will also collect another diary and surveys 3 months post-treatment.
Waitlist Available
Has No Placebo
Baylor College of Medicine/Texas Children's Hospital (+1 Sites)
Image of Weill Cornell Medical College in New York, United States.

Health Coaching for Rheumatoid Arthritis

18+
All Sexes
New York, NY
The goal of this clinical trial is to learn if peer coaching works to reduce levels of anxiety and/or depression in adults diagnosed with Rheumatoid Arthritis (RA). The main questions it aims to answer are: Do people with RA who complete the intervention with a peer coach have lower levels of anxiety and/or depression at 6 months from baseline? Do people with RA who complete the intervention with a peer coach have lower levels of anxiety and/or depression at 6 months compared to those in the control arm? Researchers will compare the peer coaching intervention to an active-control arm (where people without RA coach participants on general health and nutrition topics) to see if peer coaching works to reduce anxiety and/or depression. Participants will meet with a coach every week for 9 weeks and complete several surveys before, during and after the intervention
Recruiting
Has No Placebo
Weill Cornell Medical CollegeIris Y Navarro-Millán, MDBristol-Myers Squibb
Image of Humana Healthcare Research, Inc. in Louisville, United States.

Academic Detailing for Rheumatoid Arthritis

Any Age
All Sexes
Louisville, KY
The goal of this trial is to learn if an interactive evidence-based educational outreach visits to clinicians who prescribe biologics change prescribing of biosimilar medications. The main questions it aims to answer are: 1. Do educational outreach visits lead to a higher number of prescriptions for biosimilar versions of adalimumab? 2. Do in-person or virtual visits work better? Researchers will compare clinicians offered the educational outreach visit to those who are not offered the visit to see if there is a difference in prescribing of biosimilar versions of adalimumab instead of the original brand-name version. Participants will be offered the chance to meet with a trained clinician who will provide educational information tailored to their knowledge and attitudes on the topic. They will also be provided an educational brochure and patient educational materials.
Waitlist Available
Has No Placebo
Humana Healthcare Research, Inc. (+1 Sites)
Have you considered Ibuprofen clinical trials? We made a collection of clinical trials featuring Ibuprofen, we think they might fit your search criteria.Go to Trials
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