Seromycin

Tuberculosis, organism demonstrated to be susceptible, inadequate response to conventional therapy + 3 more
Treatment
3 FDA approvals
0 Active Studies for Seromycin

What is Seromycin

CycloserineThe Generic name of this drug
Treatment SummaryAntibiotic medication produced by a type of bacteria called Streptomyces garyphalus.
Cycloserineis the brand name
Seromycin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cycloserine
Cycloserine
1952
7

Approved as Treatment by the FDA

Cycloserine, otherwise called Cycloserine, is approved by the FDA for 3 uses such as Tuberculosis and inadequate response to conventional therapy .
Tuberculosis
Used to treat Pulmonary Tuberculosis (TB) in combination with null
inadequate response to conventional therapy
Used to treat inadequate response to conventional therapy in combination with null
Tuberculosis
Used to treat Tuberculosis, Extrapulmonary in combination with null

Effectiveness

How Seromycin Affects PatientsCycloserine is a broad-spectrum antibiotic that can kill or slow the growth of bacteria. It works by blocking the formation of peptidoglycans, which are the building blocks of a bacterial cell wall. When these walls become weakened by cycloserine, the bacteria can die.
How Seromycin works in the bodyCycloserine works to stop bacteria from growing by blocking an important step in the formation of their cell walls. It does this by preventing two enzymes from converting a certain amino acid into the chemical needed to make up the cell wall.

When to interrupt dosage

The dosage of Seromycin is contingent upon the identified issue, such as organism demonstrated to be susceptible, inadequate response to traditional treatment and Failed traditional therapy. The amount of dosage can be found in the table below, depending on the route of administration.
Condition
Dosage
Administration
Tuberculosis
, 2.5 mg/mg, 250.0 mg
, Oral, Capsule, Capsule - Oral
Urinary tract infection
, 2.5 mg/mg, 250.0 mg
, Oral, Capsule, Capsule - Oral
inadequate response to conventional therapy
, 2.5 mg/mg, 250.0 mg
, Oral, Capsule, Capsule - Oral
organism demonstrated to be susceptible
, 2.5 mg/mg, 250.0 mg
, Oral, Capsule, Capsule - Oral
Failed conventional therapy
, 2.5 mg/mg, 250.0 mg
, Oral, Capsule, Capsule - Oral
Tuberculosis
, 2.5 mg/mg, 250.0 mg
, Oral, Capsule, Capsule - Oral

Warnings

Seromycin Contraindications
Condition
Risk Level
Notes
Schizophrenia
Do Not Combine
ethanol
Do Not Combine
Depression
Do Not Combine
Kidney Failure
Do Not Combine
Anxiety
Do Not Combine
Epilepsy
Do Not Combine
There are 20 known major drug interactions with Seromycin.
Common Seromycin Drug Interactions
Drug Name
Risk Level
Description
Bacillus calmette-guerin substrain russian BCG-I live antigen
Major
The therapeutic efficacy of Bacillus calmette-guerin substrain russian BCG-I live antigen can be decreased when used in combination with Cycloserine.
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Cycloserine.
Acepromazine
Minor
Cycloserine may increase the neurotoxic activities of Acepromazine.
Aceprometazine
Minor
Cycloserine may increase the neurotoxic activities of Aceprometazine.
Acetophenazine
Minor
Cycloserine may increase the neurotoxic activities of Acetophenazine.
Seromycin Toxicity & Overdose RiskThe most toxic dose of cycloserine for mice has been found to be 5290mg/kg and for rats it is over 5000mg/kg. Overdosing on cycloserine can cause drowsiness, confusion, headache, dizziness, irritability, a feeling of numbness or tingling in the skin, difficulty speaking, paralysis, abnormal behavior, seizures, and loss of consciousness.

Seromycin Novel Uses: Which Conditions Have a Clinical Trial Featuring Seromycin?

An ongoing inquiry is assessing the effectiveness of Seromycin for Failed conventional therapy, Tuberculosis, Extrapulmonary and organisms shown to be vulnerable.
Condition
Clinical Trials
Trial Phases
Urinary tract infection
0 Actively Recruiting
Tuberculosis
0 Actively Recruiting
Failed conventional therapy
0 Actively Recruiting
Tuberculosis
0 Actively Recruiting
organism demonstrated to be susceptible
0 Actively Recruiting
inadequate response to conventional therapy
0 Actively Recruiting

Seromycin Reviews: What are patients saying about Seromycin?

3Patient Review
2/4/2011
Seromycin for Osteoporosis
This drug is great. It really helped me.
3Patient Review
2/1/2011
Seromycin for Osteoporosis
This drug is great. It really helped me.
3Patient Review
2/1/2011
Seromycin for Osteoporosis
This drug is awesome. I love drugs.
3Patient Review
2/4/2011
Seromycin for Osteoporosis
This drug is great. It really helped me.
3Patient Review
2/3/2011
Seromycin for Osteoporosis
This drug is great. It really helped me.
3Patient Review
2/4/2011
Seromycin for Osteoporosis
This drug is great. I'm grateful for modern medicine.
3Patient Review
2/3/2011
Seromycin for Osteoporosis
This drug is effective. I'm grateful for modern medicine.
3Patient Review
2/1/2011
Seromycin for Osteoporosis
This drug is effective.
3Patient Review
2/1/2011
Seromycin for Osteoporosis
This drug is great. It really helped me out.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about seromycin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What drug class is seromycin?

"Amino acids are organic compounds that have both an amino and carboxylic acid functional group, as well as a side chain that is specific to each amino acid."

Answered by AI

How is cycloserine administered?

"Doses are then increased to 500 mg twice daily for the next 2 weeks as tolerated. After 4 weeks, the dosage is adjusted according to the therapeutic response.

Seromycin can be taken orally and the current dosage suggestion is 500 mg to 1 g per day, divided into monitored doses through blood levels. The usual starting dose for adults is 250 mg, taken twice a day at 12 hour intervals, for the first 2 weeks. After that, the dosage is increased to 500 mg twice a day for the next 2 weeks if tolerated. After 4 weeks, the dosage is then adjusted according to response to the medication."

Answered by AI

What type of antibiotic is cycloserine?

"Cycloserine is a broad-spectrum antibiotic and has activity against Gram-positive and Gram-negative bacteria.

Cycloserine, trade-named Seromycin, is an antibiotic that also inhibits GABA transaminase. It is effective against Gram-positive and Gram-negative bacteria, and is prescribed as part of a regimen to treat active drug-resistant tuberculosis."

Answered by AI

What is cycloserine used for?

"Cycloserine belongs to the class of antibiotics known as bacteriostatics, and is used to treat tuberculosis. When used to treat TB, it is given in conjunction with other medications. Cycloserine may also be used to treat other conditions at the discretion of a medical practitioner."

Answered by AI
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