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What is Stadol
ButorphanolThe Generic name of this drug
Treatment SummaryNalbuphine is a synthetic painkiller used to treat extreme pain. It works by blocking the pain signals sent to the brain and has properties similar to narcotic drugs.
Stadolis the brand name
Stadol Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Stadol
Butorphanol
1996
28
Approved as Treatment by the FDA
Butorphanol, also known as Stadol, is approved by the FDA for 3 uses such as Perioperative Pain and Pain .Perioperative Pain
Pain
Pain
Effectiveness
How Stadol Affects PatientsButorphanol is a painkiller that has been around since 1978. It blocks pain signals in the brain and spine. There is now a version of this drug that can be taken through the nose, rather than through a needle. This method bypasses the stomach and intestines and is more effective, as it does not break down as much in the body. The effects of the transnasal form of butorphanol kicks in quickly and has a similar effect to the injection form.
How Stadol works in the bodyButorphanol works by interacting with opiate receptors in the brain. It's an agonist-antagonist, meaning it stimulates some opiate receptors, but blocks others. It's not totally clear how it works, but it appears to block some of the effects of opiates.
When to interrupt dosage
The endorsed measure of Stadol is contingent upon the diagnosed state, including Pain, Labor and Delivery and Chronic Pain. The portion of dosage can differ, depending on the technique of application (e.g. Spray - Nasal or Injection) detailed in the table beneath.Condition
Dosage
Administration
Pain
10.0 mg/mL, , 2.0 mg/mL, 1.0 mg/mL
Nasal, , Spray, metered, Spray, metered - Nasal, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Spray, Spray - Nasal, Aerosol, metered; Liquid, Aerosol, metered; Liquid - Nasal, Solution, Solution - Nasal, Injection, solution, Injection, solution - Intramuscular; Intravenous, Solution - Parenteral, Parenteral
Labor and Delivery
10.0 mg/mL, , 2.0 mg/mL, 1.0 mg/mL
Nasal, , Spray, metered, Spray, metered - Nasal, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Spray, Spray - Nasal, Aerosol, metered; Liquid, Aerosol, metered; Liquid - Nasal, Solution, Solution - Nasal, Injection, solution, Injection, solution - Intramuscular; Intravenous, Solution - Parenteral, Parenteral
Pain
10.0 mg/mL, , 2.0 mg/mL, 1.0 mg/mL
Nasal, , Spray, metered, Spray, metered - Nasal, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Spray, Spray - Nasal, Aerosol, metered; Liquid, Aerosol, metered; Liquid - Nasal, Solution, Solution - Nasal, Injection, solution, Injection, solution - Intramuscular; Intravenous, Solution - Parenteral, Parenteral
Chronic Pain
10.0 mg/mL, , 2.0 mg/mL, 1.0 mg/mL
Nasal, , Spray, metered, Spray, metered - Nasal, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Spray, Spray - Nasal, Aerosol, metered; Liquid, Aerosol, metered; Liquid - Nasal, Solution, Solution - Nasal, Injection, solution, Injection, solution - Intramuscular; Intravenous, Solution - Parenteral, Parenteral
Warnings
Stadol has five contraindications and should not be consumed if the individual is suffering from any of the conditions listed in the table below.Stadol ContraindicationsCondition
Risk Level
Notes
Mental Depression
Do Not Combine
Gastrointestinal obstruction
Do Not Combine
Asthma
Do Not Combine
suspected gastrointestinal obstruction
Do Not Combine
Asthma
Do Not Combine
Common Stadol Drug Interactions
Drug Name
Risk Level
Description
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline
Major
The risk or severity of adverse effects can be increased when Butorphanol is combined with 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline.
Azelastine
Major
Butorphanol may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Benmoxin
Major
The risk or severity of adverse effects can be increased when Butorphanol is combined with Benmoxin.
Brofaromine
Major
The risk or severity of adverse effects can be increased when Butorphanol is combined with Brofaromine.
Caroxazone
Major
The risk or severity of adverse effects can be increased when Butorphanol is combined with Caroxazone.
Stadol Toxicity & Overdose RiskOverdosing on butorphanol can be dangerous and lead to symptoms such as shallow breathing, decreased heart function, unconsciousness, and in extreme cases, death.
Stadol Novel Uses: Which Conditions Have a Clinical Trial Featuring Stadol?
There are 173 active trials researching the potential of Stadol to alleviate Chronic Pain, Pain and Painful Conditions.Condition
Clinical Trials
Trial Phases
Chronic Pain
149 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3, Early Phase 1
Pain
1 Actively Recruiting
Not Applicable
Pain
0 Actively Recruiting
Labor and Delivery
0 Actively Recruiting
Stadol Reviews: What are patients saying about Stadol?
5Patient Review
12/20/2007 My doctor has used this injection on me a few times when my regular migraine medication didn't take effect. I was groggy afterwards but it did help relieve the pain.
5Patient Review
11/19/2008 This medication was great for my migraine. I took it and then slept for a few hours, and when I woke up I felt so much better.
5Patient Review
10/7/2009 Stadol NS is an excellent migraine rescue medication for me, as I cannot take triptans and am allergic to most other options. It does make me very drowsy, but that is a welcome side effect when I am in the throes of a migraine. Just be aware that it is addictive if you have any tendencies in that direction.
5Patient Review
8/26/2009 Stadol is my go-to pain reliever. It's fast and it works like nothing else I've tried. Unfortunately, now that I've lost my health insurance, it's become quite expensive to purchase.
5Patient Review
1/14/2009 My doctor prescribed this to me for migraines and it's been extremely effective.
Patient Q&A Section about stadol
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Do doctors still prescribe Stadol?
"The drug is no longer being made. However, it can still be found in the US under the name of butorphanol as well as in other countries under different brand names."
Answered by AI
What are the side effects of Stadol?
"Some of the possible side effects of this medication include drowsiness, dizziness, constipation, nausea, vomiting, loss of appetite, dry mouth, warmth or redness under the skin."
Answered by AI
Why is Stadol used during labor?
"Narcotic pain medications are often given during early labor. These medications are given as an injection into the buttocks muscle or through the intravenous (IV) route during active labor."
Answered by AI
What is the drug Stadol used for?
"This medication is used to relieve moderate to severe pain, including pain from surgery, muscle pain, and migraines. It is similar to morphine in that it is an opioid pain reliever. It works by affecting certain centers in the brain that control pain."
Answered by AI