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Stimulant

Caffeine + Sodium Bicarbonate for Resistance Training Performance

Phase < 1
Recruiting
Led By David G Behm, PhD
Research Sponsored by Memorial University of Newfoundland
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up during every repetition to failure sets. each set will take a maximum of 30 seconds. with fatigue from the repetitive 6 sets, the exercise and monitoring time will decrease.

Summary

"This trial is looking at how caffeine and sodium bicarbonate supplements can affect your performance during short-term resistance training. They want to see if these supplements can help with the number of repetitions you can do,

Who is the study for?
This trial is for individuals who are interested in the effects of supplements on resistance training. Specific eligibility criteria have not been provided, but typically participants would be healthy adults engaged in regular resistance training.
What is being tested?
The study is testing how caffeine and sodium bicarbonate supplements affect short-term performance during resistance training. It will measure the number of repetitions, muscle activation, movement speed, and fatigue levels.
What are the potential side effects?
While specific side effects are not listed for this trial, common side effects from caffeine may include jitteriness, increased heart rate, or digestive discomfort; sodium bicarbonate might cause stomach upset or bloating.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~during every repetition to failure sets. each set will take a maximum of 30 seconds. with fatigue from the repetitive 6 sets, the exercise and monitoring time will decrease.
This trial's timeline: 3 weeks for screening, Varies for treatment, and during every repetition to failure sets. each set will take a maximum of 30 seconds. with fatigue from the repetitive 6 sets, the exercise and monitoring time will decrease. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Bench press repetitions to failure
Knee extensions repetitions to failure
Secondary study objectives
Blood lactate
Electromyography (EMG) root mean square (Mean amplitude)
Heart rate
+1 more

Trial Design

3Treatment groups
Experimental Treatment
Placebo Group
Group I: Sodium bicarbonateExperimental Treatment1 Intervention
Sodium bicarbonate supplement is consumed at 3 time points (120, 90 and 45 minutes prior to testing) with participants drinking 300mL of sodium bicarbonate solution at each time for a total consumed volume of 900mL. Sodium bicarbonate concentration - 0.3g/kg (Arm and Hammer brand) Each solution has MiO Liquid Water Enhancer to mask the taste.
Group II: CaffeineExperimental Treatment1 Intervention
Caffeine supplement is consumed at 3 time points (120, 90 and 45 minutes prior to testing) with participants drinking 300mL of a caffeine and water solution at each time for a total consumed volume of 900mL . Caffeine concentration - 3mg/kg or 0.003g/kg Each solution has MiO Liquid Water Enhancer to mask the taste.
Group III: ControlPlacebo Group1 Intervention
Control solution is MiO + 300mL water at 3 time points (120, 90 and 45 minutes prior to testing) with participants drinking 300mL of control solution at each time for a total consumed volume of 900mL.

Find a Location

Who is running the clinical trial?

Memorial University of NewfoundlandLead Sponsor
71 Previous Clinical Trials
1,835,839 Total Patients Enrolled
David G Behm, PhDPrincipal InvestigatorMemorial University of Newfoundland
1 Previous Clinical Trials
16 Total Patients Enrolled
~13 spots leftby Dec 2025