Green Tea, Quercetin + Chemotherapy for Prostate Cancer

Recruiting in Palo Alto (17 mi)

Overseen byPiwen Wang, PhD

Age: 18+

Sex: Male

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 1 & 2

Waitlist Available

Sponsor: Charles Drew University of Medicine and Science

Approved in 4 Jurisdictions

Trial Summary

What is the purpose of this trial?The goal of this clinical trial is to find out if taking natural products green tea and quercetin along with docetaxel chemotherapy improves the therapy of advanced prostate cancer, i.e., metastatic castration-resistant prostate cancer (mCRPC). It will also learn about the safety of this combination. Researchers will compare green tea plus quercetin to a placebo (a look-alike substance that contains no drug) in combination with docetaxel to see if green tea and quercetin works to improve the therapeutic effect of docetaxel.

Eligibility Criteria

This trial is for men with advanced prostate cancer that continues to grow despite hormone therapy. Participants must have metastatic castration-resistant prostate cancer and be suitable for docetaxel chemotherapy. Specific eligibility details are not provided, but typically include factors like age, health status, and prior treatments.

Inclusion Criteria

My cancer has worsened despite treatment with specific prostate cancer medications.

I have been diagnosed with prostate cancer that has spread.

I am willing and able to follow the study rules and attend all required visits.

+9 more

Exclusion Criteria

Ongoing alcohol abuse

Significant medical or psychiatric conditions that would make the patient a poor protocol candidate

I have received chemotherapy or radiotherapy for cancer that has spread.

+3 more

Participant Groups

The study tests if green tea and quercetin can boost the effectiveness of docetaxel chemotherapy in treating advanced prostate cancer. Patients will either receive a placebo or the natural product combination alongside their standard chemotherapy regimen.

2Treatment groups

Experimental Treatment

Placebo Group

Group I: green tea and quercetinExperimental Treatment1 Intervention

Green tea and quercetin capsules will be administered in combination with docetaxel treatment.

Group II: placeboPlacebo Group1 Intervention

Placebo capsules will be administered in combination with docetaxel treatment as comparison.

Docetaxel is already approved in United States, European Union, Canada, Japan for the following indications:

🇺🇸 Approved in United States as Taxotere for: