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Polyphenols

A Study to Evaluate the Safety and Efficacy of RQC for AMD

Phase 2
Waitlist Available
Led By Paul A Knepper, MD, PhD
Research Sponsored by Paul A Knepper, MD PhD
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 months
Awards & highlights
No Placebo-Only Group

Summary

This study is evaluating whether a combination of resveratrol, quercetin, and curcumin is safe and effective for people with age-related macular degeneration.

Eligible Conditions
  • Macular Degeneration

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Adverse Events
Change in Drusen Volume from Baseline
Geographic Atrophy (GA) Growth Rate
+1 more
Secondary study objectives
Progression to Advanced AMD

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Resveratrol, Quercetin, Curcumin (RQC)Experimental Treatment1 Intervention
Resveratrol (100mg BID), Quercetin (120mg BID), Curcumin (1000mg BID); 24 months
Group II: CurcuminActive Control1 Intervention
Curcumin (1000mg BID); 24 months

Find a Location

Who is running the clinical trial?

Paul A Knepper, MD PhDLead Sponsor
Paul A Knepper, MD, PhDPrincipal InvestigatorZaparackas Knepper, Ltd
1 Previous Clinical Trials
200 Total Patients Enrolled
Zibute Zaparackas, MDPrincipal InvestigatorZaparackas Knepper, Ltd
~35 spots leftby Dec 2025