Popular Trials
Behavioural Intervention
Adaptive Naming Treatment Schedules for Aphasia
This trial evaluates novel treatments to help people with aphasia (language disorder) improve their ability to find words, with a focus on long-term retention and use in everyday life.
Behavioral Intervention
Sentence Training for Aphasia
This trial aims to improve sentence production and comprehension in people with aphasia using a technique that subtly influences the brain to enhance language skills without the person being fully aware of it. The goal is to create lasting improvements in language abilities by frequently exposing the brain to certain language patterns.
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Trials for Hemoglobinopathy Patients
tDCS + Speech-Language Therapy for Aphasia
This trial uses a non-invasive brain stimulation technique combined with speech therapy to help stroke patients with Aphasia improve their communication skills. The brain stimulation aims to enhance the effects of language therapy by making the brain's language areas work better together. This technique has shown promise in improving language recovery in post-stroke aphasia.
Behavioural Intervention
tDCS + Speech Therapy for Aphasia
This trial is studying whether transcranial direct current stimulation (tDCS), when combined with aphasia therapy, can improve language abilities in people who have chronic, post-stroke aphasia.
Trials for Primary Progressive Aphasia Patients
Behavioural Intervention
Speech-Language Therapy for Primary Progressive Aphasia
This trial seeks to study how tailored speech-language interventions help bilingual individuals with PPA. Researchers will evaluate effects of treatment, language use, and brain scans to determine best approach.
Behavioural Intervention
Multicomponent Language Treatment for Primary Progressive Aphasia
This trial aims to help individuals with Primary Progressive Aphasia (PPA), a condition that causes a gradual decline in communication skills due to brain degeneration. The researchers want to test a new treatment approach
Behavioral Intervention
Support Group Program for Progressive Aphasia
"This trial aims to study the benefits of a support group program for people with progressive aphasia and their caregivers. They will use assessments before, after treatment, and follow-up to measure the effects of the
Behavioural Intervention
tDCS + Language Therapy for Primary Progressive Aphasia
This trial uses a gentle electrical current applied to the scalp to help patients with Primary Progressive Aphasia improve their language abilities. The treatment stimulates specific brain areas, helping the brain reorganize around damaged regions. This method has shown promise in improving language symptoms in patients with primary progressive aphasia and post-stroke aphasia.
Device
HD-tDCS + mCILT for Primary Progressive Aphasia
This trial is testing whether high-definition transcranial direct current stimulation (HD-tDCS) paired with modified constraint-induced language therapy (mCILT) can improve language performance in people with primary progressive aphasia (PPA). The study will compare changes in language performance and brain imaging before and after receiving 10 semi-consecutive daily sessions of real or sham HD-tDCS + mCILT. The 3-month follow-up will be the primary endpoint.
Trials With No Placebo
Behavioral Intervention
Telemedicine Interventions for Aphasia
This trial is testing two types of speech therapy for stroke patients who have trouble speaking. One therapy engages the right side of the brain, and the other helps with naming objects. The goal is to see which therapy improves speech better.
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Frequently Asked Questions
Introduction to aphasia
What are the top hospitals conducting aphasia research?
When it comes to advancing our understanding and treatment of aphasia, several top hospitals in the United States are leading the charge. In Baltimore, Johns Hopkins Hospital is at the forefront with six ongoing clinical trials focused on this complex communication disorder. Since recording their first trial in 2013, they have dedicated themselves to finding innovative ways to improve language and speech abilities for individuals affected by aphasia.
Meanwhile, in Milwaukee, the Medical College of Wisconsin has also made significant strides in aphasia research. With four active trials and a total of five completed studies since their inaugural trial in 2019, they are actively contributing to our knowledge of this condition and developing new interventions that can make a difference.
In Philadelphia, researchers at the University of Pennsylvania are equally committed to tackling aphasia through intensive investigation. Currently conducting four clinical trials related to this language impairment disorder and boasting an impressive history of twelve previous trials dating back to 2007; these dedicated professionals strive for breakthroughs that can enhance communication skills and quality of life for those living with aphasia.
Further south at the University of South carolina in Columbia, another group is making significant contributions. With four active aphasia trials currently underway and a total count of five completed studies since starting their initial trial in 2016; they stand as crucial players seeking improved treatments for people struggling with impaired language abilities due to various causes including stroke or brain injury.
Lastly but not least significant is The Medical University Of South Carolina where there have been notable developments regarding Aphasic impairments over years as evidenced by current involvement into yet more four on-going trialing process while successfully accomplishing seven experiments relating earlier ones which dates back around ten years ago- from specifically noting its pioneer experimentation initiated during year2012
These esteemed institutions across different locations exemplify how collaboration between medical professionals plays a pivotal role in advancing our knowledge about conditions like aphasia. Through cutting-edge research conducted within these hospitals' clinical trials programs, we inch closer to developing more effective therapies and interventions that can help individuals affected by aphasia regain their ability to communicate with the world.
Which are the best cities for aphasia clinical trials?
Baltimore, Maryland; Boston, Massachusetts; Austin, Texas; Philadelphia, Pennsylvania; and Chicago, Illinois emerge as the top cities for aphasia clinical trials. With 11 active trials in Baltimore studying interventions like Cathodal Cerebellar tDCS and SFA and PICTURE IT Intervention-CoDeLT Intervention, participants have access to cutting-edge research. Boston closely follows with 9 ongoing studies focusing on Anodal tDCS and Unison speech (vs. solo). Austin, Philadelphia, and Chicago also offer promising opportunities with 6 active trials each exploring innovative approaches such as Lexical Retrieval Training and Active TMS. These cities serve as hubs of advancement in aphasia treatment through clinical research efforts.
Which are the top treatments for aphasia being explored in clinical trials?
Aphasia, a language disorder that impacts communication abilities, is the focus of ongoing clinical trials exploring potential treatments. Among the top contenders is HD-tdcs, currently being tested in one active trial dedicated to aphasia. This innovative treatment option entered the scene in 2020 and has already garnered interest with two all-time aphasia trials under its belt. As researchers delve further into understanding this challenging condition, HD-tDCS shows promise as a potential breakthrough for individuals affected by aphasia.
What are the most recent clinical trials for aphasia?
Recent clinical trials for aphasia have shown promising advancements in the field. One notable study focuses on active transcranial direct current stimulation, which has entered both Phase 1 and Phase 2 trials as of January 1, 2023. Another trial explores the effectiveness of remotely supervised tdcs and word-naming practice in improving language abilities for individuals with aphasia. Additionally, a phase 2 trial investigates the potential benefit of using escitalopram at a dosage of 10mg specifically for treating aphasia symptoms. These studies offer hope for those affected by aphasia and highlight ongoing efforts to enhance treatment options and improve communication outcomes.
What aphasia clinical trials were recently completed?
Recently, several clinical trials investigating potential treatments for aphasia have reached significant milestones, bringing hope to individuals affected by this communication disorder. These studies focused on evaluating the efficacy of different interventions and therapies. While specific trial details vary, it is worth noting that advancements in technology and innovative approaches are being explored to address the challenges associated with aphasia. The completion of these trials signifies progress in our understanding of aphasia management and offers promise for improved outcomes in individuals living with this condition.