← Back to Search

Thrombolytic Agent

CHinese Acute Tissue-Based Imaging Selection for Lysis In Stroke -Tenecteplase II (CHABLIS-T II Trial)

Phase 2
Waitlist Available
Research Sponsored by Huashan Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24-36 hours
Awards & highlights
No Placebo-Only Group

Summary

To explore the efficacy and safety of tenecteplase for acute ischemic stroke patients (onset time 4.5-24h) of large vessel occlusion using early combined CT/MR imaging outcomes

Eligible Conditions
  • Stroke

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24-36 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24-36 hours for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Intracranial Hemorrhage
Angiogram
patients without endovascular therapy obtained >50% reperfusion at 4-6 hours
Secondary study objectives
Barthel index
Clinical efficacy outcome: NIHSS change
Clinical efficacy outcome: NIHSS change at 7 days
+15 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: Tenecteplase armExperimental Treatment1 Intervention
Group II: Best treatment arm (e.g. Aspirin, Recombinant Tissue Plasminogen Activator, Urokinase, Thrombectomy)Experimental Treatment1 Intervention
The best treatment selected by local doctors
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
The best treatment selected by local doctors(Aspirin, Recombinant Tissue Plasminogen Activator, Urokinase, Thrombectomy)
2021
Completed Phase 2
~230
Tenecteplase
2020
Completed Phase 4
~6200

Find a Location

Who is running the clinical trial?

Shanghai 7th People's HospitalOTHER
5 Previous Clinical Trials
1,690 Total Patients Enrolled
1 Trials studying Stroke
200 Patients Enrolled for Stroke
Puer People's HospitalUNKNOWN
Nanshi Hospital of NanyangUNKNOWN
3 Previous Clinical Trials
2,032 Total Patients Enrolled
3 Trials studying Stroke
2,032 Patients Enrolled for Stroke
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineUNKNOWN
Shanghai Fifth People's Hospital,Fudan UniversityUNKNOWN
3 Previous Clinical Trials
489 Total Patients Enrolled
the Third Hospital of MianyangUNKNOWN
1 Previous Clinical Trials
200 Total Patients Enrolled
Huizhou Municipal Central HospitalOTHER
67 Previous Clinical Trials
712,248 Total Patients Enrolled
12 Trials studying Stroke
228,731 Patients Enrolled for Stroke
Hexigten Traditional Chinese and Mongolian Medicine HospitalUNKNOWN
Zhejiang UniversityOTHER
433 Previous Clinical Trials
4,123,304 Total Patients Enrolled
8 Trials studying Stroke
1,427 Patients Enrolled for Stroke
Yangpu Hospital, School of Medicine, Tongji UniversityUNKNOWN
~53 spots leftby Jan 2026
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top