What side effects are associated with this type of intervention?

Common treatments for lung transplant complications include immunosuppressive medications and supportive therapies. Treatments similar to live music therapy, such as music therapy itself, are generally well-tolerated and have minimal side effects. These therapies aim to reduce anxiety, pain, and improve mood and sleep quality. Known side effects are rare but may include temporary emotional discomfort or overstimulation in some patients. Overall, these therapies are considered safe and beneficial for enhancing the overall well-being of post-lung transplant patients.

What prior FDA approvals exist?

The FDA has approved various pharmacological treatments for lung transplant complications, including immunosuppressants like tacrolimus to prevent organ rejection and manage lung injury. However, non-pharmacological treatments such as live music therapy, which aims to reduce anxiety, pain, and improve mood, are still under investigation. These therapies focus on creating a calming environment, providing distraction from pain, and enhancing overall well-being, but they have not yet received FDA approval specifically for lung transplant complications.

What other types of research exist?

Promising alternatives to Live Music Therapy for lung transplant patients include: <ol> <li>Guided Imagery: This technique involves visualizing calming and positive scenarios, which can reduce anxiety and pain.</li> <li></li> </ol> Biofeedback: This method helps patients control physiological functions such as heart rate and muscle tension, promoting relaxation and pain management. 3. Mindfulness-Based Stress Reduction (MBSR): This program combines mindfulness meditation and yoga to reduce stress and improve mood. 4. Cognitive-Behavioral Therapy (CBT): This therapy helps patients manage pain and anxiety by changing negative thought patterns. 5. Clinical Hypnosis: This technique can help manage pain and anxiety through focused attention and relaxation.

← Back to Search

Music Therapy for Post-Operative Lung Transplant Care

N/A

Waitlist Available

Led By Emily Pickett

Research Sponsored by University of Texas Southwestern Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Must not have

Post-lung transplant patients with chests left open directly after OR (before being taken back to the OR and having their chests closed)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up changes from baseline to post-surgery day 6

Awards & highlights

No Placebo-Only Group

Summary

This trial is testing if live music therapy can help lung transplant patients feel less pain and anxiety, use fewer medications, stay in the hospital for a shorter time, and sleep better. The therapy involves a music therapist playing the patient's favorite music.

Who is the study for?

This trial is for post-lung transplant patients at UTSW Clements University Hospital starting June 1, 2021. It's not suitable for those whose chests were left open after surgery and before being taken back to the OR for closure.

What is being tested?

The study tests if live music therapy can lower anxiety and pain, reduce use of benzodiazepines and pain meds, shorten ICU/hospital stay, and improve sleep quality in post-lung transplant patients.

What are the potential side effects?

Since this trial involves music therapy rather than medication or invasive procedures, significant side effects are not expected. However, individual responses to music therapy may vary.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

My chest was left open immediately after my lung transplant surgery.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ changes from baseline to post-surgery day 6

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~changes from baseline to post-surgery day 6

This trial's timeline: 3 weeks for screening, Varies for treatment, and changes from baseline to post-surgery day 6 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in Anxiety levels

Change in Pain levels (CPOT)

Change in Pain levels (Pain number scale)

+5 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Music Therapy GroupExperimental Treatment1 Intervention

Group II: Control GroupActive Control1 Intervention

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Music Therapy

2019

Completed Phase 3

~1660

0 / 1Eligibility criteria met

Research Highlights

Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.

Mechanism Of Action

Side Effect Profile

Prior Approvals

Other Research

Common treatments for lung transplant complications include immunosuppressive medications to prevent rejection, antibiotics to treat infections, and therapies to manage chronic conditions like bronchiolitis obliterans syndrome. Complementary therapies, such as music therapy, play a crucial role by providing relaxation, reducing anxiety, and improving mood, which can enhance overall recovery and quality of life. These therapies are particularly important as they offer non-pharmacological options to manage pain and stress, potentially reducing the need for additional medications and their associated side effects.

Adult respiratory distress syndrome following thoracic trauma.Ex vivo administration of trimetazidine improves post-transplant lung function in pig model.Mechanical Ventilation in Adults with Acute Respiratory Distress Syndrome. Summary of the Experimental Evidence for the Clinical Practice Guideline.