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Hormone Therapy

PROMOTE Study: Prediction of Response Of HorMOnal Treatment in Advanced and Recurrent Endometrial Cancer (PROMOTE Trial)

N/A
Recruiting
Led By Hanny Pijnenborg, MD PhD
Research Sponsored by Radboud University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights
No Placebo-Only Group
All Individual Drugs Already Approved
Approved for 10 Other Conditions

Summary

The PROMOTE study aims at optimising use of hormonal therapy in advanced stage and recurrent endometrial cancer analysing tumor tissue taken before start of hormonal therapy

Eligible Conditions
  • Endometrial Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Clinical benefit rate
Progression free survival
Response rate
Secondary study objectives
Health-related quality of life

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
Approved for 10 Other Conditions
This treatment demonstrated efficacy for 10 other conditions.

Trial Design

1Treatment groups
Experimental Treatment
Group I: EC patients with HTExperimental Treatment1 Intervention
Patients with advanced stage or recurrent endometrial cancer treated with hormonal therapy

Find a Location

Who is running the clinical trial?

Radboud UniversityLead Sponsor
728 Previous Clinical Trials
298,405 Total Patients Enrolled
3 Trials studying Endometrial Cancer
78 Patients Enrolled for Endometrial Cancer
The Netherlands Cancer InstituteOTHER
302 Previous Clinical Trials
214,405 Total Patients Enrolled
1 Trials studying Endometrial Cancer
12 Patients Enrolled for Endometrial Cancer
Hospital del MarOTHER
89 Previous Clinical Trials
443,898 Total Patients Enrolled
Leiden University Medical CenterOTHER
558 Previous Clinical Trials
607,145 Total Patients Enrolled
5 Trials studying Endometrial Cancer
3,251 Patients Enrolled for Endometrial Cancer
Catharina Ziekenhuis EindhovenOTHER
150 Previous Clinical Trials
127,450 Total Patients Enrolled
Canisius-Wilhelmina HospitalOTHER
47 Previous Clinical Trials
31,685 Total Patients Enrolled
Royal Cornwall Hospitals TrustOTHER
26 Previous Clinical Trials
36,434 Total Patients Enrolled
3 Trials studying Endometrial Cancer
516 Patients Enrolled for Endometrial Cancer
Hospital Vall d'HebronOTHER
92 Previous Clinical Trials
69,464 Total Patients Enrolled
1 Trials studying Endometrial Cancer
103 Patients Enrolled for Endometrial Cancer
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER
706 Previous Clinical Trials
2,718,174 Total Patients Enrolled
1 Trials studying Endometrial Cancer
40 Patients Enrolled for Endometrial Cancer
Erasmus Medical CenterOTHER
710 Previous Clinical Trials
2,098,455 Total Patients Enrolled
~66 spots leftby Oct 2026