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Procedure

MRI for Brain Blood Flow During Exercise

N/A
Recruiting
Led By Jill N Barnes, PhD
Research Sponsored by University of Wisconsin, Madison
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Healthy men or women between the ages of 20-40 years old
Be between 18 and 65 years old
Must not have
Vulnerable populations (e.g., pregnant women, prisoners, individuals lacking capacity to consent)
Have a body mass index ≥30 kg/m2
Timeline
Screening 3 weeks
Treatment Varies
Follow Up one study visit, up to 120 minutes
Awards & highlights
No Placebo-Only Group

Summary

"This trial will measure blood flow in the brain during exercise using magnetic resonance imaging."

Who is the study for?
This trial is for healthy men and women aged 20-40 who exercise regularly, at least three times a week for 30 minutes. They should be familiar with using cardio exercise equipment but not have a high BMI, any major health issues like heart or kidney disease, or contraindications to MRI.
What is being tested?
The study measures how blood flows in the brain during exercise using an MRI. Participants will perform aerobic physical activities while their brain's blood flow responses are monitored.
What are the potential side effects?
Since the intervention involves only MRI scanning during exercise, there are no direct side effects from drugs or invasive procedures. However, MRIs can cause discomfort due to loud noises and confinement.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am a healthy adult aged between 20 and 40.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I am not pregnant, imprisoned, or unable to consent for myself.
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My BMI is 30 or higher.
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I have a history of liver, kidney, blood, heart diseases, high blood pressure, vascular disease, stroke, or diabetes.
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I am at least 71 inches tall.
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I do not fall within the required age range for the trial.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~one study visit, up to 120 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and one study visit, up to 120 minutes for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Cerebral Blood Flow
Cerebral Hemodynamics

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Young AdultsExperimental Treatment1 Intervention
Young Adults between 20-40 years of age.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
MRI
2009
Completed Phase 2
~2810

Find a Location

Who is running the clinical trial?

University of Wisconsin, MadisonLead Sponsor
1,232 Previous Clinical Trials
3,200,002 Total Patients Enrolled
17 Trials studying Stroke
271,286 Patients Enrolled for Stroke
Jill N Barnes, PhDPrincipal InvestigatorUniversity of Wisconsin, Madison
7 Previous Clinical Trials
461 Total Patients Enrolled
~10 spots leftby Jun 2025
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