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Dextrose-Enhanced Anesthetic for Chronic Pain
N/A
Waitlist Available
Research Sponsored by The Seekers Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Present chronic pain symptoms of at least 3 months in duration
Currently receiving injection therapy every 1-3 weeks for at least 6 months
Must not have
Age less than 18 years
Scar or infection at the blockade puncture site
Timeline
Screening 3 weeks
Treatment Varies
Follow Up bpi is administered at the following intervals: first visit (baseline/week 1), the third visit (week 5), the sixth and final visit (week 11), and again four weeks after the end of the intervention period (week 15).
Awards & highlights
No Placebo-Only Group
Summary
This trial aims to see if adding a 5% dextrose solution to a local anesthetic can help improve outcomes for patients with chronic non-cancer pain. Researchers want to know if injecting d
Who is the study for?
This trial is for individuals with chronic non-cancer pain who regularly receive trigger point injections or peripheral nerve blockade. Participants must be able to attend treatment every two weeks for three months and complete several questionnaires about their health and pain levels.
What is being tested?
The study is testing if adding a small amount (5%) of dextrose to the usual local anesthetic improves long-term pain relief in patients. It's a single-arm, open-label trial where everyone gets the same intervention without being compared to a control group.
What are the potential side effects?
Since this trial involves commonly used local anesthetics with added dextrose, side effects may include typical reactions to injection such as discomfort at the injection site, bruising, infection risk, and possible allergic reactions.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I have been experiencing chronic pain for at least 3 months.
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I have been on injection therapy every 1-3 weeks for at least 6 months.
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I am under 18 years old.
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I have a scar or infection where I might receive an injection.
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I do not have any unstable mental health conditions.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ the phq-9 is administered at the following intervals: at the first visit (baseline/week 1), the third visit (week 5), the sixth and final visit (week 11), and again four weeks after the end of the intervention period (week 15).
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~the phq-9 is administered at the following intervals: at the first visit (baseline/week 1), the third visit (week 5), the sixth and final visit (week 11), and again four weeks after the end of the intervention period (week 15).
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Brief Pain Inventory form (BPI)
Patient Health Questionnaire (PHQ-9)
Patient's Global Impression of the Change (PGIC)
+1 moreAwards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
1Treatment groups
Experimental Treatment
Group I: Addition of 1 mL of 50% dextrose solution to the usual local anesthetic solution of choiceExperimental Treatment1 Intervention
The physician will add 1 mL of 50% dextrose solution (Pfizer Canada ULS, Kirkland, Québec) to the usual local anesthetic solution of choice for each patient. Solutions contain either 0.3% Ropivacaine, 1% Procaine, 0.5% Lidocaine, 0.25% Bupivacaine, or a mixture of 0.25% Bupivacaine and 2% Lidocaine in a 9:1 ratio.
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Who is running the clinical trial?
The Seekers CentreLead Sponsor