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Orton Score System for Colonoscopy Preparation

N/A

Waitlist Available

Led By Steven M Powell, MD

Research Sponsored by University of Virginia

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Referred for open access colonoscopy from an outside provider/UVA provider

Age 18 or older (up to 100 years)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up through study duration, approximately 1 year

Summary

This trial is testing a new system for prescribing a specific bowel prep to patients most at risk for an inadequate prep, in order to decrease the number of incomplete or cancelled procedures.

Who is the study for?

This trial is for adults aged 18 to 100 who are referred for an open access colonoscopy from outside or UVA providers and can give informed consent. It's not suitable for prisoners.

What is being tested?

The study tests a new scoring system, the Orton Score, against typical standard care to improve bowel prep before outpatient colonoscopies. The goal is to reduce inadequate preps and increase polyp detection without randomizing patients.

What are the potential side effects?

While specific side effects aren't listed, bowel prep generally may cause discomfort such as cramping, bloating, nausea or vomiting. Extended prep might increase these sensations.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I was referred for a colonoscopy by another doctor.

Select...

I am between 18 and 100 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ through study duration, approximately 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~through study duration, approximately 1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and through study duration, approximately 1 year for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Inadequate prep rate

Secondary study objectives

Adenoma detection rate (ADR)

Advanced adenoma / adenocarcinoma detection rate

Incomplete colonoscopy rate

+1 more

Trial Design

3Treatment groups

Experimental Treatment

Active Control

Placebo Group

Group I: Retrospective Cohort (before Orton Score)Experimental Treatment1 Intervention

Group II: Orton Score Cohort - HighActive Control1 Intervention

Patients will be scored using the "Orton Score," a novel clinical prediction tool to determine which patients are at risk for poor bowel preps and may benefit from an extended prep. If they score highly, they will receive an extended GoLytely bowel prep.

Group III: Prospective Orton Score Cohort - LowPlacebo Group1 Intervention

Patients will be scored using the "Orton Score," a novel clinical prediction tool to determine which patients are at risk for poor bowel preps and may benefit from an extended prep. If they do not score highly, they will receive a standard GoLytely (or Suprep) bowel prep.

0 / 2Eligibility criteria met