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Mindfulness-Based Stress Reduction for Diabetes (De-Stress Trial)

N/A
Waitlist Available
Led By Nazia T Raja-Khan, M.D., M.S.
Research Sponsored by Milton S. Hershey Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age 18 years or older
Hemoglobin A1c ≥ 7.5% within 10 weeks and 2 days (72 days) before the start of the study intervention (Orientation session)
Must not have
Inpatient admission for psychiatric disorder within the past two years, or ER visit for psychiatric disorder within the past 10 weeks
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and 6 months
Awards & highlights
No Placebo-Only Group

Summary

This trial will compare the effects of an online mindfulness-based stress reduction intervention to an active control stress management education on glucose control in adults with uncontrolled type 1 or type 2 diabetes.

Who is the study for?
Adults with uncontrolled type 1 or type 2 diabetes, high stress levels, and an HbA1c level of at least 7.5% can join this study. Participants need internet access for online sessions and must have been diagnosed with diabetes for over a year. Exclusions include certain psychiatric conditions, current pregnancy, enrollment in other studies or stress programs, and non-English speakers.
What is being tested?
The trial is testing the effectiveness of an online Mindfulness-based Stress Reduction (MBSR) program against Stress Management Education (SME) to improve glucose control in diabetics. The study involves live virtual classes over six months with follow-ups to compare the two methods.
What are the potential side effects?
Since this trial focuses on stress reduction techniques rather than medication, side effects are minimal but may include discomfort from discussing personal issues during sessions or potential frustration if no improvement in stress levels is perceived.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am 18 years old or older.
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My last Hemoglobin A1c level was 7.5% or higher.
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I have been diagnosed with diabetes for over a year.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I haven't been admitted for psychiatric reasons in the last 2 years or visited the ER for one in the last 10 weeks.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and 6 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change in Hemoglobin A1c from Baseline to 6 months
Secondary study objectives
Change in Diabetes Distress Scale from Baseline to 2 months
Change in Diabetes Distress Scale from Baseline to 6 months
Change in Hemoglobin A1c from Baseline to 2 months
+2 more

Side effects data

From 2013 Phase 4 trial • 89 Patients • NCT01033851
2%
muscle soreness
100%
80%
60%
40%
20%
0%
Study treatment Arm
Mindfulness Based Stress Reduction
Stress Management Education

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Mindfulness Based Stress ReductionExperimental Treatment1 Intervention
Group II: Stress Management EducationActive Control1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Mindfulness Based Stress Reduction
2016
Completed Phase 4
~3570

Find a Location

Who is running the clinical trial?

Milton S. Hershey Medical CenterLead Sponsor
511 Previous Clinical Trials
2,870,551 Total Patients Enrolled
Penn State UniversityOTHER
370 Previous Clinical Trials
127,696 Total Patients Enrolled
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NIH
2,464 Previous Clinical Trials
4,337,144 Total Patients Enrolled
West Chester University of PennsylvaniaOTHER
5 Previous Clinical Trials
1,023 Total Patients Enrolled
Georgetown UniversityOTHER
350 Previous Clinical Trials
138,856 Total Patients Enrolled
Rowan UniversityOTHER
24 Previous Clinical Trials
2,655 Total Patients Enrolled
National Institutes of Health (NIH)NIH
2,843 Previous Clinical Trials
8,172,924 Total Patients Enrolled
Nazia T Raja-Khan, M.D., M.S.Principal InvestigatorMilton S. Hershey Medical Center

Media Library

Mindfulness Based Stress Reduction Clinical Trial Eligibility Overview. Trial Name: NCT04016415 — N/A
Type 2 Diabetes Research Study Groups: Mindfulness Based Stress Reduction, Stress Management Education
Type 2 Diabetes Clinical Trial 2023: Mindfulness Based Stress Reduction Highlights & Side Effects. Trial Name: NCT04016415 — N/A
Mindfulness Based Stress Reduction 2023 Treatment Timeline for Medical Study. Trial Name: NCT04016415 — N/A
~57 spots leftby Jan 2026