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Optical Coherence Tomography of Tear Film Dynamics In-Vivo

N/A
Waitlist Available
Led By Jannick Rolland, PhD
Research Sponsored by University of Rochester
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up participants will be seen once within a one year period, on average within 1 month
Awards & highlights
No Placebo-Only Group

Summary

The purpose of this study is to evaluate a new instrument that takes digital images of tear film (a thin film that coats the eye that is made up of oil and water). The investigators are interested in measuring how the thickness of the tear film varies through time. The goal is to develop a technique that may enable non-invasive evaluation of Dry Eye Disease for future clinical diagnosis.

Eligible Conditions
  • Dry Eye Syndrome

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~participants will be seen once within a one year period, on average within 1 month
This trial's timeline: 3 weeks for screening, Varies for treatment, and participants will be seen once within a one year period, on average within 1 month for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Thickness of aqueous layers on patient cornea (um)
Thickness of lipid layers on patient cornea (nm)
Secondary study objectives
Optical aberrations
Thickness maps dynamics

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Dry Eye DiseaseExperimental Treatment1 Intervention
Optical Coherence Tomography
Group II: NormalsActive Control1 Intervention
Optical Coherence Tomography

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Who is running the clinical trial?

University of RochesterLead Sponsor
872 Previous Clinical Trials
549,966 Total Patients Enrolled
Jannick Rolland, PhDPrincipal InvestigatorUniversity of Rochester
~0 spots leftby Dec 2025
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