What side effects are associated with this type of intervention?

Common treatments for atopic dermatitis include topical corticosteroids, moisturizers, and vitamin D supplementation. Topical corticosteroids can cause skin thinning (atrophy) and should be used cautiously, especially on sensitive areas like the face. Moisturizers are generally safe but may cause irritation in some individuals. Vitamin D supplementation has shown potential benefits but requires more research to confirm its efficacy and safety. Overall, these treatments are effective but should be monitored for potential side effects.

What prior FDA approvals exist?

The FDA has approved several treatments for Atopic Dermatitis, including biologics like dupilumab and tralokinumab, which have shown significant efficacy in reducing symptoms. Dupilumab, in particular, has been noted for its effectiveness in achieving a 75% reduction in the Eczema Area and Severity Index (EASI-75) score. These treatments are relevant to the trial studying animation-style videos for patient education, as visual and engaging content can enhance understanding and adherence to these advanced therapies. Additionally, systemic therapies like cyclosporine and methotrexate have been used, though they come with more significant side effects. The focus on animation-style videos aims to improve patient outcomes by making complex treatment regimens more accessible and easier to follow.

What other types of research exist?

Promising alternatives to animation-style videos for atopic dermatitis patient education include: 1) Illustrated Eczema Action Plans, which have shown high usability and usefulness among caregivers and patients. 2) Comprehensive, standardized treatment protocols that incorporate emerging eczema therapies and guidelines, as suggested by the National Eczema Association. 3) Interactive web-based learning programs, which have been effective in other dermatological conditions like skin cancer. These alternatives can provide engaging, accessible, and effective education for atopic dermatitis patients.

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Educational Materials for Eczema (AD-TPE Trial)

N/A

Waitlist Available

Led By Margaret Lee, MD PhD

Research Sponsored by Boston University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Boston Medical Center (BMC) patients under the age of 18 diagnosed with AD and their parents/legal guardian

Be younger than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

No Placebo-Only Group

Summary

This trial tests whether educational videos or paper handouts are more effective in teaching children with atopic dermatitis about managing their condition. The goal is to see which method helps improve their symptoms and quality of life.

Who is the study for?

This trial is for Boston Medical Center patients under 18 with Atopic Dermatitis (AD) and their parents or guardians, who speak Spanish or English and have internet access. There are no specific exclusion criteria.

What is being tested?

The study is testing if animated videos are better than printed materials at teaching patients about AD management. It looks at how these methods affect the severity of AD, sleep quality, and itchiness levels in participants.

What are the potential side effects?

Since this trial involves educational materials rather than medical treatments, there are no direct side effects associated with the interventions being tested.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am under 18, diagnosed with AD, and a patient at BMC or I am their parent/legal guardian.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in eczema severity based on the Eczema Area and Severity Index (EASI)

Change in eczema severity based on the Patient Oriented Eczema Measure (POEM)

Change in sleep quality

+1 more

Secondary study objectives

Atopic Dermatitis related costs

Change in knowledge of coping with Atopic Dermatitis (AD)

Change in patient/parent confidence

+2 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Group 2- Educational videosExperimental Treatment1 Intervention

Parent-child dyads randomized to this group will receive an investigator developed educational video in English or Spanish about atopic dermatitis.

Group II: Group 1- Printed educational materialsActive Control1 Intervention

Parent-child dyads randomized to this group will receive printed educational materials in English or Spanish about atopic dermatitis.

0 / 1Eligibility criteria met

Research Highlights

Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.

Mechanism Of Action

Side Effect Profile

Prior Approvals

Other Research

The most common treatments for Atopic Dermatitis (AD) include topical corticosteroids, which reduce inflammation and suppress immune responses; topical immunomodulators, which modulate the immune system to decrease inflammation; and phototherapy, which uses UV light to reduce skin inflammation and itch. Educational interventions, such as animation-style videos, play a crucial role by improving patient understanding and adherence to treatment regimens. Enhanced patient education ensures that patients are well-informed about their condition and treatment options, leading to better management of symptoms and overall disease control.

European guideline (EuroGuiDerm) on atopic eczema - part II: non-systemic treatments and treatment recommendations for special AE patient populations.The Use of Acellular Fish Skin Grafts in Burn Wound Management-A Systematic Review.Young people's perceptions of acne and acne treatments: secondary analysis of qualitative interview data.