← Back to Search

STXBP1 and SYNGAP1 Related Disorders Natural History Study

N/A
Recruiting
Led By Ingo Helbig, MD
Research Sponsored by Children's Hospital of Philadelphia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up every 6 months upto 5 years
Awards & highlights
No Placebo-Only Group

Summary

The purpose of this study is to find out more about STXBP1 and SYNGAP1 related disorders. The information gathered by this study will be used to prepare for clinical treatment trials. The primary objective of the study is to better define and outline the clinical spectrum of STXBP1 and SYNGAP1 through detailed developmental, seizure, and quality of life assessments as an extension of routine clinical care.

Eligible Conditions
  • Inherited disorder
  • Encephalopathy
  • Intellectual disability

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~every 6 months upto 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and every 6 months upto 5 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Changes in percentiles recorded on clinical assessments over time

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: SYNGAP1 cohortExperimental Treatment1 Intervention
Group II: STXBP1 cohortExperimental Treatment1 Intervention

Find a Location

Who is running the clinical trial?

Children's Hospital of PhiladelphiaLead Sponsor
731 Previous Clinical Trials
8,472,640 Total Patients Enrolled
STXBP1 FoundationUNKNOWN
1 Previous Clinical Trials
50 Total Patients Enrolled
Ingo Helbig, MDPrincipal InvestigatorChildren's Hospital of Philadelphia
~267 spots leftby Aug 2028