← Back to Search

Cartilage Repair Agent

Microfracture with BST-CarGel for Knee Injuries

N/A
Waitlist Available
Led By William Stanish, MD
Research Sponsored by Piramal Healthcare Canada Ltd
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months
Awards & highlights

Summary

This study will investigate whether the treatment of damaged cartilage in the knee with BST-CarGel will increase the amount and quality of cartilage repair tissue when compared with microfracture alone. Furthermore, the effect of BST-CarGel in decreasing cartilage related pain and improving cartilage-related function in the knee will be assessed.

Eligible Conditions
  • Knee Injuries

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Degree of Filling of the Lesion by Repair Tissue at 12 Months Through MRI.
Repair Cartilage T2 Relaxation Time
Secondary study objectives
Change From Baseline for Knee-related Pain, Stiffness and Function at 12 Months (WOMAC Parts A, B, C)

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Microfracture with BST-CarGelExperimental Treatment1 Intervention
BST-CarGel applied to a Microfractured lesion in repair of focal articular cartilage lesions on the femoral condyle
Group II: Microfracture without BST-CarGelActive Control1 Intervention
Microfractured lesion in repair of focal articular cartilage lesions on the femoral condyle
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
BST-CarGel with Microfracture
2005
N/A
~80

Find a Location

Who is running the clinical trial?

Piramal Healthcare Canada LtdLead Sponsor
2 Previous Clinical Trials
72 Total Patients Enrolled
1 Trials studying Knee Injuries
67 Patients Enrolled for Knee Injuries
William Stanish, MDPrincipal InvestigatorOrthopaedic and Sport Medicine - Dalhousie University
~4 spots leftby Oct 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top