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Behavioral Intervention
High-Intensity Gait Training for Multiple Sclerosis
N/A
Recruiting
Research Sponsored by University of Illinois at Chicago
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Age ≥21 years
Multiple sclerosis diagnosis
Must not have
Severe osteoporosis
Unexplained, recurring headaches
Timeline
Screening 3 weeks
Treatment Varies
Follow Up immediately (within 1 week) before and after training
Awards & highlights
No Placebo-Only Group
Summary
This trial aims to see if high-intensity walking exercise can help improve fatigue and walking problems in people with multiple sclerosis. This could potentially enhance their quality of life and reduce the economic burden associated with the
Who is the study for?
This trial is for people with Multiple Sclerosis who experience fatigue and walking difficulties. Specific eligibility criteria are not provided, but typically participants must meet certain health conditions to ensure safety and effectiveness of the treadmill training intervention.
What is being tested?
The study investigates if high-intensity gait training on a treadmill can reduce fatigue and improve walking in individuals with Multiple Sclerosis. The goal is to see if this type of exercise could enhance their quality of life.
What are the potential side effects?
While specific side effects are not listed, high-intensity treadmill training may cause muscle soreness, increased fatigue initially, or exacerbate symptoms in some individuals with Multiple Sclerosis.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am 21 years old or older.
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I have been diagnosed with multiple sclerosis.
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My treatment for my condition has not changed in the last 6 months.
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I often feel very tired.
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I can walk for 6 minutes, even with a cane or walker.
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I have difficulty walking due to my condition.
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I have been diagnosed with severe osteoporosis.
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I often have headaches for no clear reason.
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I have had skull abnormalities or fractures.
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I have a neurological condition that is not multiple sclerosis.
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I do not have uncontrolled heart, lung, or metabolic conditions.
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I am unable to give consent for myself.
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I am taking medication that could make me more prone to seizures.
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I have metal implants in my head or face.
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I have had a multiple sclerosis flare-up in the last month.
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I have a history of seizures or epilepsy.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ immediately (within 1 week) before and after training
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~immediately (within 1 week) before and after training
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Corticomotor excitability
Symptomatic fatigue
Walking speed
Secondary study objectives
Aerobic capacity
Fatigue impact
Verbal learning and memory
+2 moreOther study objectives
Community ambulation
Interhemispheric inhibition
Spatial walking symmetry
+1 moreAwards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: High-intensity interval treadmill trainingExperimental Treatment1 Intervention
Walking with high intensity intervals interspersed.
Group II: Moderate-intensity continuous treadmill trainingActive Control1 Intervention
Continuous walking at a moderate intensity
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
treadmill training
2015
N/A
~50
Find a Location
Who is running the clinical trial?
University of Illinois at ChicagoLead Sponsor
640 Previous Clinical Trials
1,568,769 Total Patients Enrolled
15 Trials studying Multiple Sclerosis
1,799 Patients Enrolled for Multiple Sclerosis