Behavioral Intervention
Three-Tier Support Model for Adverse Childhood Experiences
Recruiting1 award2 criteria
Loma Linda, California
This trial is studying whether a combination of different types of support can improve outcomes for children with ACEs. Families with children between the ages of 3 and 11 who have recently seen a pediatrician are invited to participate.
Sirolimus for Tuberous Sclerosis
Recruiting0 awardsPhase 2
Birmingham, Alabama
This trial is testing sirolimus, a medication that helps control symptoms of Tuberous Sclerosis Complex (TSC), in infants. The goal is to prevent or delay seizures, which can impact long-term brain development. Sirolimus works by turning down the activity of a center in the body that doesn't function properly in TSC. Sirolimus has been studied for its potential to control seizures in pediatric patients with TSC and has shown promising results in improving seizure control.
Behavioural Intervention
IPSRT + Healthy Lifestyle Intervention for Bipolar Disorder Risk
Recruiting1 award4 criteria
Pittsburgh, Pennsylvania
This trial tests a telehealth therapy called IPSRT to help children at high risk of bipolar disorder due to having a bipolar parent. The therapy focuses on improving sleep and daily routines to prevent the disorder. The study will monitor outcomes over time. Interpersonal and Social Rhythm Therapy (IPSRT) was specifically developed to manage stressful life events, improve disruptions in social and circadian rhythms, and has shown efficacy in treating bipolar disorder.
Popular Filters
Trials for Major Depressive Disorder Patients
Behavioral Intervention
Behavioral Activation for Alcohol Use Disorder
Recruiting1 awardPhase 2
Lawrence, Kansas
This trial will test a new way to help college freshmen who drink too much alcohol. The intervention will address concerns that are most relevant to these students and be integrated into the college curriculum.
Behavioral Intervention
Counseling for Depression and Suicide Risk
Recruiting1 award
Portland, Oregon
This trial is testing whether an anonymous online screening for stress, depression, substance use, and suicidal thoughts will help medical trainees and faculty who are in distress. It is expected that the screening will make them more likely to come for counseling and that their suicide risk factors will be lower after they receive treatment.
Mindfulness-Based Intervention
Mindfulness Training for Mood Disorders
Recruiting1 award
Pittsburgh, Pennsylvania
This trial will test a mindfulness-based intervention to improve mood regulation in early adolescents at high risk for developing mood disorders, in order to better understand how and for whom mindfulness interventions work.
Omega-3 Fatty Acids
Vitamin D + Omega-3 for Depression
Recruiting0 awards
Boston, Massachusetts
This trial is studying whether taking vitamin D3 or omega-3 fatty acids supplements reduces the risk of developing cancer, heart disease, and stroke. This study will also examine whether either of these supplements reduces the risk of clinical depression or improves mood scores over time.
Non-invasive Brain Stimulation
Brain Stimulation + Cognitive Remediation for Preventing Alzheimer's
Recruiting0 awards10 criteria
Toronto, Ontario
This trial will compare the efficacy of a non-invasive brain stimulation combined with cognitive remediation versus a sham ("placebo") stimulation combined with a sham ("placebo") cognitive remediation in slowing down cognitive decline and preventing Alzheimer's Dementia in older persons with mild cognitive impairment or major depressive disorder with or without mild cognitive impairment.
Trials for Persistent Depressive Disorder Patients
Behavioral Intervention
Behavioral Activation for Alcohol Use Disorder
Recruiting1 awardPhase 2
Lawrence, Kansas
This trial will test a new way to help college freshmen who drink too much alcohol. The intervention will address concerns that are most relevant to these students and be integrated into the college curriculum.
Behavioral Intervention
Counseling for Depression and Suicide Risk
Recruiting1 award
Portland, Oregon
This trial is testing whether an anonymous online screening for stress, depression, substance use, and suicidal thoughts will help medical trainees and faculty who are in distress. It is expected that the screening will make them more likely to come for counseling and that their suicide risk factors will be lower after they receive treatment.
Mindfulness-Based Intervention
Mindfulness Training for Mood Disorders
Recruiting1 award
Pittsburgh, Pennsylvania
This trial will test a mindfulness-based intervention to improve mood regulation in early adolescents at high risk for developing mood disorders, in order to better understand how and for whom mindfulness interventions work.
Omega-3 Fatty Acids
Vitamin D + Omega-3 for Depression
Recruiting0 awards
Boston, Massachusetts
This trial is studying whether taking vitamin D3 or omega-3 fatty acids supplements reduces the risk of developing cancer, heart disease, and stroke. This study will also examine whether either of these supplements reduces the risk of clinical depression or improves mood scores over time.
Non-invasive Brain Stimulation
Brain Stimulation + Cognitive Remediation for Preventing Alzheimer's
Recruiting0 awards10 criteria
Toronto, Ontario
This trial will compare the efficacy of a non-invasive brain stimulation combined with cognitive remediation versus a sham ("placebo") stimulation combined with a sham ("placebo") cognitive remediation in slowing down cognitive decline and preventing Alzheimer's Dementia in older persons with mild cognitive impairment or major depressive disorder with or without mild cognitive impairment.
Phase 3 Trials
Macrolide Antibiotic
Azithromycin for Reducing Infections After C-Section
Recruiting1 awardPhase 3
Birmingham, Alabama
This trial is testing whether giving azithromycin along with standard antibiotics to 8,000 women having a cesarean delivery can help reduce infections after childbirth. The study will compare the rates of
Trials With No Placebo
Behavioral Intervention
Behavioral Activation for Alcohol Use Disorder
Recruiting1 awardPhase 2
Lawrence, Kansas
This trial will test a new way to help college freshmen who drink too much alcohol. The intervention will address concerns that are most relevant to these students and be integrated into the college curriculum.
Behavioral Intervention
Integrated Care Management for Lupus
Recruiting1 award3 criteria
Boston, Massachusetts
This trialwill study lupus patients at BWH to identify those at high risk of adverse outcomes, and offer intensive care management to reduce avoidable ED visits, hospitalizations and improve high quality care.
Behavioral Intervention
Dissonance-Based Obesity Prevention + Response and Attention Training for Obesity
Recruiting1 award
Eugene, Oregon
This trial is testing whether a novel obesity prevention program is more effective when done in single-sex versus mixed-sex groups, and whether adding food response and attention training increases weight gain prevention effects.
Behavioural Intervention
Risk-Based Screening for Breast Cancer
Recruiting1 award4 criteria
Birmingham, Alabama
This trial is comparing annual breast cancer screening to a risk-based breast cancer screening schedule. The goal is to see if the risk-based schedule detects breast cancers earlier and causes fewer false positives.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.