Vitamin
Vitamin D + Fish Oil for Health Improvement
This trial is studying whether taking daily dietary supplements of vitamin D3 or omega-3 fatty acids reduces the risk of developing cancer, heart disease, and stroke in people who do not have a prior history of these illnesses.
mTOR inhibitor
Sirolimus for Tuberous Sclerosis
This trial is testing sirolimus, a medication that helps control symptoms of Tuberous Sclerosis Complex (TSC), in infants. The goal is to prevent or delay seizures, which can impact long-term brain development. Sirolimus works by turning down the activity of a center in the body that doesn't function properly in TSC. Sirolimus has been studied for its potential to control seizures in pediatric patients with TSC and has shown promising results in improving seizure control.
Behavioural Intervention
IPSRT + Healthy Lifestyle Intervention for Bipolar Disorder Risk
This trial tests a telehealth therapy called IPSRT to help children at high risk of bipolar disorder due to having a bipolar parent. The therapy focuses on improving sleep and daily routines to prevent the disorder. The study will monitor outcomes over time. Interpersonal and Social Rhythm Therapy (IPSRT) was specifically developed to manage stressful life events, improve disruptions in social and circadian rhythms, and has shown efficacy in treating bipolar disorder.
Popular Filters
Trials for Major Depressive Disorder Patients
Behavioral Intervention
Counseling for Depression and Suicide Risk
This trial is testing whether an anonymous online screening for stress, depression, substance use, and suicidal thoughts will help medical trainees and faculty who are in distress. It is expected that the screening will make them more likely to come for counseling and that their suicide risk factors will be lower after they receive treatment.
Mindfulness-Based Intervention
Mindfulness Training for Mood Disorders
This trial will test a mindfulness-based intervention to improve mood regulation in early adolescents at high risk for developing mood disorders, in order to better understand how and for whom mindfulness interventions work.
Behavioral Intervention
Behavioral Activation for Alcohol Use Disorder
This trial will test a new way to help college freshmen who drink too much alcohol. The intervention will address concerns that are most relevant to these students and be integrated into the college curriculum.
Omega-3 Fatty Acids
Vitamin D + Omega-3 for Depression
This trial is studying whether taking vitamin D3 or omega-3 fatty acids supplements reduces the risk of developing cancer, heart disease, and stroke. This study will also examine whether either of these supplements reduces the risk of clinical depression or improves mood scores over time.
Non-invasive Brain Stimulation
Brain Stimulation + Cognitive Remediation for Preventing Alzheimer's
This trial will compare the efficacy of a non-invasive brain stimulation combined with cognitive remediation versus a sham ("placebo") stimulation combined with a sham ("placebo") cognitive remediation in slowing down cognitive decline and preventing Alzheimer's Dementia in older persons with mild cognitive impairment or major depressive disorder with or without mild cognitive impairment.
Behavioural Intervention
ER + NH + CM Interventions for Suicide Prevention
This trial will test which combination of three interventions (New Hope, Elders Resilience, and Case Management) is most effective at reducing suicidal ideation and increasing resilience in American Indian adolescents.
Trials for Persistent Depressive Disorder Patients
Behavioral Intervention
Counseling for Depression and Suicide Risk
This trial is testing whether an anonymous online screening for stress, depression, substance use, and suicidal thoughts will help medical trainees and faculty who are in distress. It is expected that the screening will make them more likely to come for counseling and that their suicide risk factors will be lower after they receive treatment.
Mindfulness-Based Intervention
Mindfulness Training for Mood Disorders
This trial will test a mindfulness-based intervention to improve mood regulation in early adolescents at high risk for developing mood disorders, in order to better understand how and for whom mindfulness interventions work.
Behavioral Intervention
Behavioral Activation for Alcohol Use Disorder
This trial will test a new way to help college freshmen who drink too much alcohol. The intervention will address concerns that are most relevant to these students and be integrated into the college curriculum.
Omega-3 Fatty Acids
Vitamin D + Omega-3 for Depression
This trial is studying whether taking vitamin D3 or omega-3 fatty acids supplements reduces the risk of developing cancer, heart disease, and stroke. This study will also examine whether either of these supplements reduces the risk of clinical depression or improves mood scores over time.
Non-invasive Brain Stimulation
Brain Stimulation + Cognitive Remediation for Preventing Alzheimer's
This trial will compare the efficacy of a non-invasive brain stimulation combined with cognitive remediation versus a sham ("placebo") stimulation combined with a sham ("placebo") cognitive remediation in slowing down cognitive decline and preventing Alzheimer's Dementia in older persons with mild cognitive impairment or major depressive disorder with or without mild cognitive impairment.
Behavioural Intervention
ER + NH + CM Interventions for Suicide Prevention
This trial will test which combination of three interventions (New Hope, Elders Resilience, and Case Management) is most effective at reducing suicidal ideation and increasing resilience in American Indian adolescents.
Phase 3 Trials
Macrolide Antibiotic
Azithromycin for Reducing Infections After C-Section
This trial is testing whether giving azithromycin along with standard antibiotics to 8,000 women having a cesarean delivery can help reduce infections after childbirth. The study will compare the rates of
Trials With No Placebo
Behavioral
Computerized Decision Support for Blood Clot Prevention
This trial is a single-center, 400-patient, randomized controlled trial of an EPIC Best Practice Advisory (BPA; alert-based computerized decision support tool) to increase prescription of extended-duration post-discharge thromboprophylaxis and decrease symptomatic VTE in high-risk patients hospitalized with medical illness.
Behavioral Intervention
Dissonance-Based Obesity Prevention + Response and Attention Training for Obesity
This trial is testing whether a novel obesity prevention program is more effective when done in single-sex versus mixed-sex groups, and whether adding food response and attention training increases weight gain prevention effects.
Behavioural Intervention
Risk-Based Screening for Breast Cancer
This trial is comparing annual breast cancer screening to a risk-based breast cancer screening schedule. The goal is to see if the risk-based schedule detects breast cancers earlier and causes fewer false positives.
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Frequently Asked Questions
Introduction to prevention
What are the top hospitals conducting prevention research?
When it comes to groundbreaking clinical trials in the field of prevention, several top hospitals across the United States are making notable strides. Brigham and Women's Hospital in Boston leads the way with six active prevention trials aimed at identifying strategies to ward off various diseases. While they have yet to conduct any prevention trials historically, their commitment to preventive medicine is evident. Similarly, Mayo Clinic in Rochester is actively engaged in four ongoing prevention studies, focusing on innovative approaches to disease prevention. Although they also do not have a past record of conducting preventive trials, their dedication towards exploring preventative measures is commendable.
In Aurora, Colorado, Children's Hospital Colorado recognizes the importance of early intervention and has three active prevention trials underway. These efforts aim to identify ways to prevent or mitigate health issues from an early age and support children's well-being as they grow up.
Meanwhile, Dent Neurologic Institute located in Amherst acknowledges that preventing neurological disorders carries immense significance for overall health outcomes. They currently contribute by running three active clinical trials focused on preventive strategies within this realm.
Lastly,nestled away in Bellevue,the Northwest Clinical Research Center signifies its role as a crucial player by hosting three ongoing preventive clinical investigations without prior historical input.Their current endeavors involve pioneering research into preventative measures against various conditions related issues emphasizing their contribution towards ensuring healthier lives
These esteemed institutions demonstrate unwavering commitment toward mitigating risks before diseases surface and promoting overall wellness through proactive approaches.Across different locations these top-tier hospitals exemplify how ongoing collaborative work continues driving us closer than ever before towards cultivating healthier lives for everyone
Which are the best cities for prevention clinical trials?
When it comes to prevention clinical trials, several cities have emerged as leaders in research and development. Boston, Massachusetts leads the way with 18 active trials focusing on interventions like Enteric Coated Aspirin, Deferoxamine, and Vitamin d. New york, New York follows closely behind with 13 ongoing studies examining strategies such as targeted screening advice based on comprehensive risk assessments. Miami, Florida; Phoenix, Arizona; and Baltimore Maryland also contribute significantly to prevention research with their own set of active trials exploring various preventive measures. These cities offer individuals opportunities to participate in cutting-edge clinical trials aimed at preventing diseases and improving overall health outcomes.
Which are the top treatments for prevention being explored in clinical trials?
When it comes to prevention, clinical trials are currently investigating the efficacy of several promising treatments. The top contenders in these trials include:
- Daratumumab: Being tested in multiple ongoing trials
- Belantamab mafodotin: Showing potential as a preventive treatment
- Lenalidomide: Under investigation for its preventive properties
These treatments hold promise for preventing breast cancer and may provide a breakthrough in the fight against this disease. Continued research and development are crucial to improving prevention strategies and ultimately reducing the burden of breast cancer worldwide.
What are the most recent clinical trials for prevention?
Exciting advancements are being made in the realm of prevention, as recent clinical trials offer promising approaches to safeguard against various health conditions. Among these studies is a Phase 2 trial investigating the efficacy of high-dose ORC-13661 for prevention. Additionally, a Phase 3 trial called ReMMiD-C Therapeutic Arm A aims to explore preventive strategies further. Another Phase 3 trial named ROSE (Reach Out, Stay Strong, Essentials) focuses on preventing complications in mothers with newborns. Furthermore, a Phase 2 trial examines the potential benefits of smartphones in preventive measures. Lastly, Stellate ganglion block is being explored through both Phase 2 and Phase 3 trials for its preventative properties. With these innovative initiatives underway, we can anticipate significant progress in disease prevention efforts moving forward.
What prevention clinical trials were recently completed?
Recently, several clinical trials focused on prevention have concluded, providing valuable insights into strategies for disease avoidance. These studies demonstrate the commitment of researchers to proactively addressing health concerns.