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EPR Oximetry for Peripheral Neuropathy (CIPN Trial)

N/A

Waitlist Available

Led By Victoria H Lawson, M.D.

Research Sponsored by Dartmouth-Hitchcock Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 year

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to see if measuring tissue oxygen and testing blood for a specific protein can detect early nerve damage in breast cancer patients undergoing treatment.

Eligible Conditions

Chemotherapy-induced Peripheral Neuropathy

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Relative Change in % pO2

Secondary study objectives

Change in Nerve Conduction Metrics (Amplitude)_MED PLANTAR

Change in Nerve Conduction Metrics (Amplitude)_SURAL

Change in Nerve Conduction/Mixed Nerve Amplitudes _Medial Plantar

+41 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: EPR OximetryExperimental Treatment1 Intervention

All subjects in the study will receive the paramagnetic India ink injection to the foot. At three time points (pre-exposure, during-exposure or CIPN incidence, and post exposure), subjects will have three EPR oximetry readings, a neurological examination, and electrophysiologic testing.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

EPR Oximetry

2018

N/A

~10

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