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Behavioural Intervention
Blood Flow Restriction Training for Parkinson's Disease
N/A
Waitlist Available
Led By Anjali Sivaramakrishnan, PhD, PT
Research Sponsored by The University of Texas Health Science Center at San Antonio
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
In Hoehn and Yahr stage 2-4
Males and females between the ages 40 - 85 with a diagnosis of idiopathic Parkinson's Disease (PD) consistent with the United Kingdom PD society brain bank criteria
Must not have
History of cardiovascular disease, uncontrolled hypertension (blood pressure ≥140/90 mmHg), orthostatic hypotension, deep-vein thrombosis, varicose veins, or rhabdomyolysis
History of other neurological disorders affecting the central nervous system such as stroke, multiple sclerosis, tumors, amyotrophic lateral sclerosis or muscle disease such as muscular dystrophy, myopathy
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to14 weeks
Awards & highlights
No Placebo-Only Group
Summary
This trial aims to investigate how limiting blood flow during balance exercises can potentially help alleviate symptoms of Parkinson's disease.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
My Parkinson's disease is at a moderate to advanced stage.
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I am between 40-85 years old and have been diagnosed with Parkinson's Disease.
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I have a history of heart disease or uncontrolled high blood pressure.
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I have a history of neurological or muscle disorders like stroke or MS.
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I am pre-menopausal and not using birth control.
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I am planning to undergo major surgery within the next 2 months.
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I do not have uncontrolled diabetes, severe osteoporosis, or cognitive issues.
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My BMI is above 40, indicating I might have poorer muscle function and more pain.
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I had surgery on my legs or feet in the last 6 months.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline to14 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to14 weeks
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Feasibility metric
Secondary study objectives
Ankle plantar flexor muscle strength
Balance Measure
Functional Mobility
+6 moreAwards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
2Treatment groups
Experimental Treatment
Group I: IRT Only Control GroupExperimental Treatment1 Intervention
Instability Resistance Training only group. Participants will receive 2 sessions per week over 6 weeks.
Group II: BFR plus IRT GroupExperimental Treatment2 Interventions
Blood Flow Restriction plus Instability Resistance Training group. Participants will receive 2 sessions per week over 6 weeks.
Find a Location
Who is running the clinical trial?
The University of Texas Health Science Center at San AntonioLead Sponsor
477 Previous Clinical Trials
92,950 Total Patients Enrolled
National Institute on Aging (NIA)NIH
1,805 Previous Clinical Trials
28,194,837 Total Patients Enrolled
Anjali Sivaramakrishnan, PhD, PTPrincipal InvestigatorThe University of Texas Health Science Center at San Antonio