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Gastric Cancer Patients Undergoing Neoadjuvant Chemotherapy for Stomach Cancer

N/A
Recruiting
Research Sponsored by Chinese Academy of Sciences
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up three years
Awards & highlights

Summary

This study seeks to develop a deep-learning-based intelligent predictive model for the efficacy of neoadjuvant chemotherapy in gastric cancer patients. By utilizing the patients' CT imaging data, biopsy pathology images, and clinical information, the intelligent model will predict the post-neoadjuvant chemotherapy efficacy and prognosis, offering assistance in personalized treatment decisions for gastric cancer patients.

Eligible Conditions
  • Stomach Cancer
  • Imaging
  • Pathology

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~five years
This trial's timeline: 3 weeks for screening, Varies for treatment, and five years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Accuracy of TRG prediction by the AI model
Area under the receiver operating characteristic curve (AUC) for TRG prediction by the AI model
Secondary outcome measures
Overall Survival (OS) at 5 years
Progression-Free Survival (PFS) at 3 years

Trial Design

1Treatment groups
Experimental Treatment
Group I: Gastric Cancer Patients Undergoing Neoadjuvant ChemotherapyExperimental Treatment1 Intervention
This group comprises participants diagnosed with advanced gastric cancer. The participants will be treated with standard neoadjuvant chemotherapy regimens recommended by clinical guidelines. Treatment details, including the generic name of the drugs, dosage form, dosage, frequency, and duration, will be recorded according to the specific regimen.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Neoadjuvant Chemotherapy
2014
Completed Phase 2
~340

Find a Location

Who is running the clinical trial?

Peking University People's HospitalOTHER
613 Previous Clinical Trials
6,489,271 Total Patients Enrolled
Tianjin Medical University Cancer Institute and HospitalOTHER
386 Previous Clinical Trials
177,634 Total Patients Enrolled
Chinese Academy of SciencesLead Sponsor
101 Previous Clinical Trials
34,045,838 Total Patients Enrolled
~100 spots leftby Sep 2025
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