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Behavioral Intervention

CPT-Text for Post-Traumatic Stress Disorder (CPT-TEXT Trial)

N/A
Recruiting
Led By Shannon Wiltsey-Stirman, PhD
Research Sponsored by Stanford University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Significant symptoms of PTSD as evidenced by a score of 33 or above on the PCL-5
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline through 24 weeks at 3 timepoints
Awards & highlights

CPT-TEXT Trial Summary

This trial will compare a texting-based therapy for PTSD against a similar therapy that is tailored to be more culturally sensitive. It will also compare an incentive strategy against reminders to prevent people from discontinuing therapy early.

Who is the study for?
This trial is for adults in the US with significant PTSD symptoms that started or worsened during COVID-19. Participants must score 33+ on the PCL-5, have experienced a Criterion A event, be registered on Talkspace for therapy, and own a texting device. It's not open to those with acute psychosis, substance abuse needing higher care level, or high suicide risk.Check my eligibility
What is being tested?
The study tests two PTSD treatments delivered via text: Culturally Informed Trauma Treatment (CITT) and CPT-Text against usual reminders. It also examines if incentives help patients stick with therapy longer compared to standard platform reminders.See study design
What are the potential side effects?
As this trial involves psychological interventions through texting rather than medication, side effects may include emotional discomfort due to discussing traumatic events but are unlikely to involve physical side effects.

CPT-TEXT Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I have severe PTSD symptoms, scoring 33 or higher on a specific test.

CPT-TEXT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline through 24 weeks, at 3 timepoints
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline through 24 weeks, at 3 timepoints for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
PTSD Checklist for DSM-5 (PCL-5)
Secondary outcome measures
Behavioral Intention
Cultural Humility Scale (CHS)
Cultural Missed Opportunities (CMO)
+7 more

CPT-TEXT Trial Design

4Treatment groups
Experimental Treatment
Active Control
Group I: CPT-Text + Reminder As UsualExperimental Treatment2 Interventions
CPT-Text. CPT is a 12-session, trauma-focused, cognitive therapy that teaches clients to examine and change problematic beliefs about themselves and the world that were altered as a result of trauma. Reminder as Usual (RAU). As per Talkspace guidelines, therapists are available to client participants twice per day, five days per week. In the event a client participant has not engaged or messaged in 48 hours, therapists send a personalized message to the client participant to encourage them to re-engage.
Group II: CPT-Text + IncentiveExperimental Treatment2 Interventions
CPT-Text. CPT is a 12-session, trauma-focused, cognitive therapy that teaches clients to examine and change problematic beliefs about themselves and the world that were altered as a result of trauma. Retention Incentive (RI). Participants will be told at baseline that they can earn discounts for other users with PTSD if they message with their therapist regularly.
Group III: Culturally Informed Trauma Treatment (CITT) + IncentiveActive Control2 Interventions
CITT will be conducted by Talkspace therapists with a specialty in PTSD culturally informed PTSD treatment. Retention Incentivefor other users with PTSD in subsequent months if they message with their therapist regularly.
Group IV: CITT+ Reminder as UsualActive Control2 Interventions
CITT will be conducted by Talkspace therapists with a specialty in culturally informed PTSD treatment. Reminder as Usual (RAU). As per Talkspace guidelines, therapists are available to client participants twice per day, five days per week. In the event a client participant has not engaged or messaged in 48 hours, therapists send a personalized message to the client participant to encourage them to re-engage.

Find a Location

Who is running the clinical trial?

Stanford UniversityLead Sponsor
2,408 Previous Clinical Trials
17,343,007 Total Patients Enrolled
The University of Texas Health Science Center at San AntonioOTHER
455 Previous Clinical Trials
91,008 Total Patients Enrolled
TalkspaceIndustry Sponsor
4 Previous Clinical Trials
14,606 Total Patients Enrolled

Media Library

CPT-Text (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05037175 — N/A
Post-Traumatic Stress Disorder Research Study Groups: CPT-Text + Incentive, Culturally Informed Trauma Treatment (CITT) + Incentive, CITT+ Reminder as Usual, CPT-Text + Reminder As Usual
Post-Traumatic Stress Disorder Clinical Trial 2023: CPT-Text Highlights & Side Effects. Trial Name: NCT05037175 — N/A
CPT-Text (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05037175 — N/A
~116 spots leftby Jun 2025
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