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Randomized Controlled Trial to Evaluate the Impact of ZYN Nicotine Pouch Products on Cigarette Usage and BoExp in Adult Smokers Over a 12-week Period

N/A
Waitlist Available
Research Sponsored by Swedish Match AB
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up measured from baseline to week 12
Awards & highlights
No Placebo-Only Group

Summary

To verify whether unrestricted access to flavored products is likely to lead to greater reductions in combustible cigarette smoking and decreased exposure to smoking related toxicants.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~measured from baseline to week 12
This trial's timeline: 3 weeks for screening, Varies for treatment, and measured from baseline to week 12 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (total NNAL) in urine

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Active Control
Group I: tobacco flavor and unflavored options of ZYNActive Control1 Intervention
Group II: (control) continue smoking their usual brand of CCActive Control1 Intervention
Group III: unrestricted flavor options of ZYNActive Control1 Intervention

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Who is running the clinical trial?

Swedish Match ABLead Sponsor
6 Previous Clinical Trials
680 Total Patients Enrolled
Brian E Erkkila, PhDStudy ChairSwedish Match
~186 spots leftby Jan 2026