Probiotic
Probiotics for Long COVID Symptoms
Recruiting0 awards3 criteria
Milwaukee, Wisconsin
This trial tests whether taking a probiotic called Lp299v can help people who have long-term symptoms after COVID-19. The probiotic aims to reduce inflammation and improve blood vessel function. Adults aged 18-89 with these symptoms will take the supplement for a period of time to see if it helps. Probiotics have shown benefits in a variety of diseases, including respiratory infections, and may be beneficial in the adjunctive treatment of COVID-19.
Behavioural Intervention
Broccoli Sprouts for Healthy Eating
Recruiting0 awards5 criteria
Corvallis, Oregon
This trial will study the effects of broccoli sprouts on the human body at a molecular and metabolic level. It will also look at the composition of the microbiome (the microorganisms that live in the gut).
Behavioural Intervention
Diet Intervention for Juvenile Arthritis
Recruiting1 award1 criteria
Winnipeg, Manitoba
This trial aims to investigate whether a Mediterranean Diet-based diet can improve arthritis in children by studying its effects on the gut microbiome. Fifty-four participants will change their diet for 8 weeks, with the
Prebiotic
Prebiotics for PTSD and Liver Cirrhosis
Recruiting1 award3 criteria
Richmond, Virginia
"This trial investigates the relationship between PTSD, cirrhosis, and gut microbiome in Veterans. Patients with both PTSD and cirrhosis have greater cognitive impairment and changes in gut microbiome compared to those
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Trials for Microbial Colonization Patients
Microbiota Transplant
Nasal Bacteria Transfer for Neonatal Infections
Recruiting0 awardsPhase 1
Baltimore, Maryland
This trial will investigate if transferring nasal bacteria from parents to newborns can introduce the parents' bacteria into the newborns' microbiome and improve the diversity of bacteria in the newborns.
Procedure
Nasal Microbiota Transplant for Preventing Newborn Infections
Recruiting0 awardsPhase 1
Baltimore, Maryland
This trial is testing if transferring healthy bacteria from a parent's nose to their newborn's nose can help protect the baby from harmful bacteria. The study focuses on newborns at Johns Hopkins Hospital. By creating a healthy bacterial environment in the baby's nose, the researchers hope to reduce the risk of infections.
Microbiome Therapy
Nasal Microbiota Transplant for Staphylococcus aureus Colonization
Recruiting0 awardsPhase 1
Baltimore, Maryland
This trial will study how nasal manual therapy (NMT) impacts the variety of bacteria in the noses of children after they have been treated with mupirocin medication sprayed into the nose.
Selective Serotonin and Norepinephrine Reuptake Inhibitor
Microbiome Influence on Drug Metabolism
Recruiting2 awardsPhase 1
Somerville, New Jersey
This trial will study how drugs are metabolized by the microbiome in humans, in parallel with preclinical studies. The investigators will be able to confirm the relevance of microbiome-derived metabolism in vivo, create microbiome-dependent PK profiles of the drugs, and establish methodology to capture the contribution of microbiome-derived metabolism to inter-individual variability in clinical drug PK profiles.
Trials for Crohn's Disease Patients
Behavioural Intervention
Fasting-Mimicking Diet for Inflammatory Bowel Disease-Related Depression
Recruiting1 awardPhase < 1
Edmonton, Alberta
This trial is investigating the effects of a fasting mimicking diet on IBD patients who are suffering from symptoms of depression. The goal is to develop a safe and effective treatment to improve mental health in patients with IBD by targeting the gut microbiome through dietary interventions.
Microbiome Therapy
Fecal Microbiota Transplant for Clostridium Difficile and IBD
Recruiting1 awardPhase 1
Philadelphia, Pennsylvania
This trial will study the safety and effectiveness of Fecal Microbiota Transplants (FMT) in children with recurrent C. Difficile infections, with or without Inflammatory Bowel Disease (IBD). 454 pyrosequencing will be used to study the gut microbiota before and after transplantation.
Behavioural Intervention
Dietary Therapy for Crohn's Disease and Ulcerative Colitis
Recruiting1 award
Boston, Massachusetts
This trial tests two special diets to help people with active Crohn's Disease or Ulcerative Colitis. One diet is a liquid nutrient formula, and the other limits certain carbs. The goal is to see if these diets can improve gut health and reduce symptoms.
Dietary Intervention
Diet-CD for Crohn's Disease During Pregnancy
Recruiting1 award4 criteria
Worcester, Massachusetts
This trial tests if a special diet during pregnancy can improve gut health in women with Crohn's disease and their babies. The goal is to create a healthier balance of gut bacteria, which may help reduce disease relapse in mothers and lower gut inflammation in babies. The study will collect various samples to analyze the effects of the diet.
Trials With No Placebo
Behavioural Intervention
Fasting-Mimicking Diet for Inflammatory Bowel Disease-Related Depression
Recruiting1 awardPhase < 1
Edmonton, Alberta
This trial is investigating the effects of a fasting mimicking diet on IBD patients who are suffering from symptoms of depression. The goal is to develop a safe and effective treatment to improve mental health in patients with IBD by targeting the gut microbiome through dietary interventions.
Behavioural Intervention
High-Fiber Diet for Satiety
Recruiting1 award14 criteria
Columbia, Missouri
This trial is testing a high fiber diet made from peas on overweight/obese adults and those with metabolic syndrome. The diet aims to slow nutrient absorption and produce substances in the gut that increase fullness and improve health. Pea fiber has been studied for its potential to improve weight control and metabolic health in overweight and obese adults.
Trials Offering Remuneration
Microbiota Transplant
Nasal Bacteria Transfer for Neonatal Infections
Recruiting0 awardsPhase 1
Baltimore, Maryland
This trial will investigate if transferring nasal bacteria from parents to newborns can introduce the parents' bacteria into the newborns' microbiome and improve the diversity of bacteria in the newborns.
Procedure
Nasal Microbiota Transplant for Preventing Newborn Infections
Recruiting0 awardsPhase 1
Baltimore, Maryland
This trial is testing if transferring healthy bacteria from a parent's nose to their newborn's nose can help protect the baby from harmful bacteria. The study focuses on newborns at Johns Hopkins Hospital. By creating a healthy bacterial environment in the baby's nose, the researchers hope to reduce the risk of infections.
Microbiome Therapy
Nasal Microbiota Transplant for Staphylococcus aureus Colonization
Recruiting0 awardsPhase 1
Baltimore, Maryland
This trial will study how nasal manual therapy (NMT) impacts the variety of bacteria in the noses of children after they have been treated with mupirocin medication sprayed into the nose.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.