Fluocinonide

Inflammation, Dermatosis, Itching
Treatment
5 FDA approvals
20 Active Studies for Fluocinonide

What is Fluocinonide

FluocinonideThe Generic name of this drug
Treatment SummaryA topical steroid used to reduce inflammation and treat eczema.
Fluocinonideis the brand name
image of different drug pills on a surface
Fluocinonide Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fluocinonide
Fluocinonide
1984
147

Approved as Treatment by the FDA

Fluocinonide, otherwise known as Fluocinonide, is approved by the FDA for 5 uses like Inflammation and Itching .
Inflammation
Used to treat Inflammation in combination with Gramicidin D
Itching
Used to treat Pruritus in combination with Gramicidin D
Inflammation
Used to treat Inflammation in combination with Gramicidin D
Pruritus
Used to treat Pruritus in combination with Gramicidin D
Dermatosis
Used to treat Dermatosis in combination with Gramicidin D

Effectiveness

How Fluocinonide Affects PatientsFluocinonide is a strong medicine used to reduce inflammation and treat skin conditions like eczema. It helps reduce itching, redness, dryness, crusting, scaling, inflammation, and other discomforts caused by skin inflammation.
How Fluocinonide works in the bodyFluocinonide is a steroid used to reduce inflammation in the skin. It binds to a receptor in the cell nucleus and causes changes in gene expression. Fluocinonide works by blocking the production of substances called prostaglandins and leukotrienes, which are responsible for inflammation. It also blocks the action of certain proteins that help cells stick together and move around. The steroid also weakens the immune system by reducing lymphocytes and other immune system components. Finally, it interferes with the body's ability to create and use energy, leading to increased glucose levels in the blood.

When to interrupt dosage

The prescribed dosage of Fluocinonide is contingent upon the determined condition, including Inflammation, Dermatosis and Itch. The amount of dosage likewise varies, in accordance with the technique of delivery (e.g. Topical or Jelly - Topical) featured in the table beneath.
Condition
Dosage
Administration
Inflammation
, 0.0005 mg/mg, 0.5 mg/mL, 0.001 mg/mg, 0.05 %, 0.01 %, 0.00005 mg/mg
, Gel, Gel - Topical, Topical, Ointment, Ointment - Topical, Cream, Cream - Topical, Solution - Topical, Solution, Jelly, Jelly - Topical, Cream; Emulsion, Cream; Emulsion - Topical, Kit, Kit - Topical
Dermatosis
, 0.0005 mg/mg, 0.5 mg/mL, 0.001 mg/mg, 0.05 %, 0.01 %, 0.00005 mg/mg
, Gel, Gel - Topical, Topical, Ointment, Ointment - Topical, Cream, Cream - Topical, Solution - Topical, Solution, Jelly, Jelly - Topical, Cream; Emulsion, Cream; Emulsion - Topical, Kit, Kit - Topical
Itching
, 0.0005 mg/mg, 0.5 mg/mL, 0.001 mg/mg, 0.05 %, 0.01 %, 0.00005 mg/mg
, Gel, Gel - Topical, Topical, Ointment, Ointment - Topical, Cream, Cream - Topical, Solution - Topical, Solution, Jelly, Jelly - Topical, Cream; Emulsion, Cream; Emulsion - Topical, Kit, Kit - Topical

Warnings

There are 20 known major drug interactions with Fluocinonide.
Common Fluocinonide Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Fluocinonide is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Fluocinonide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abatacept
Major
The risk or severity of adverse effects can be increased when Fluocinonide is combined with Abatacept.
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Fluocinonide.
Abetimus
Major
The risk or severity of adverse effects can be increased when Fluocinonide is combined with Abetimus.
Fluocinonide Toxicity & Overdose RiskPossible side effects of using this drug include acne, burning sensation, dry skin, increased hair growth, skin infections, irritation, itching, discoloration, heat rash, inflammation, skin thinning or softening, and stretch marks.
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Fluocinonide Novel Uses: Which Conditions Have a Clinical Trial Featuring Fluocinonide?

Currently, 200 active clinical trials are assessing the potential of Fluocinonide to alleviate Itch, Inflammation and Dermatosis.
Condition
Clinical Trials
Trial Phases
Dermatosis
0 Actively Recruiting
Inflammation
58 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4
Itching
2 Actively Recruiting
Phase 3, Not Applicable

Fluocinonide Reviews: What are patients saying about Fluocinonide?

5Patient Review
6/24/2017
Fluocinonide for Psoriasis of Scalp
This solution is essential to my life. I have scalp psoriasis and it's the only thing that works for me. It might burn at first, but soon enough you'll start noticing a difference.
5Patient Review
10/24/2017
Fluocinonide for Skin Condition
This cream quickly and effectively relieved both my chigger bites and the rash that developed from sweating and friction.
5Patient Review
2/5/2021
Fluocinonide for Skin Condition
This ointment, prescribed by my podiatrist has done an excellent job of clearing up my foot fungus. However, it hasn't cured the problem entirely. I'm also not a fan of ointments in general, so that's why it only gets four stars from me.
5Patient Review
3/27/2019
Fluocinonide for Itching
I've been using this for years with great success. Whenever I have an area of severe itching, I apply a thin film and the sensation subsides within hours - it never returns!
5Patient Review
5/15/2016
Fluocinonide for Atopic Dermatitis
This medication has been working wonders for my eczema. It cleared up the rash within just a couple of days, and if I start to feel an itch coming on, I can apply it and prevent the redness and blisters from even forming. I'm really amazed at how well this medication works!
4Patient Review
5/2/2017
Fluocinonide for Atopic Dermatitis
While this medication did clear the redness, I found myself feeling really down and depressed. This was strange and surprising to me, so I wanted to warn others in case this could be a more serious side effect for someone with an underlying condition.
2.7Patient Review
12/10/2017
Fluocinonide for Psoriasis of Scalp
It's hard to use this treatment by yourself, but it did clear up my scalp psoriasis. However, the symptoms came back after I stopped using it for a week. Another downside is that I experienced a lot of hair loss.
2.7Patient Review
8/23/2021
Fluocinonide for Itching
I didn't see any reduction in itchiness when using this cream, unfortunately.
2.3Patient Review
3/30/2018
Fluocinonide for Rash
I was admitted to the hospital for cellulitis on my arm and then started breaking out with an itchy rash. I have been to four different doctors, and one prescribed medication for a fungus under my nails which I didn't have. I am hoping that this cream will work because the itch is driving me insane. It's spreading from my armpits to my chest, between my legs, and up my neck. The instructions say not to use it on your armpits, but it seems to be worse in areas that are moist. If anyone has any advice, please let me know.
2.3Patient Review
3/22/2019
Fluocinonide for Itching
I was really hoping this would help me more than it did. It's not that it didn't work at all, but I still have a long way to go before finding something that completely eliminates my itchiness.
1Patient Review
8/22/2017
Fluocinonide for Skin Rash that Becomes Thick & Discolored From Rubbing It
I started taking this medication and - while it did stop the severe itching I was experiencing from eczema - it caused huge, pus-filled bumps that were incredibly inflamed. My face also broke out in terrible acne. Needless to say, I stopped taking this medication.
1Patient Review
1/6/2021
Fluocinonide for Skin Condition
The 0.01% concentration didn't help me at all. I'm wondering if a stronger dose would've made a difference.
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Patient Q&A Section about fluocinonide

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is fluocinonide cream an antifungal?

"No, fluocinonide (Vanos) is not an antifungal medication. It is a corticosteroid. Depending on your personal skin condition, you might be prescribed fluocinonide (Vanos) and an antifungal at the same time."

Answered by AI

What are side effects of fluocinonide?

"Possible side effects of the medication include: painful and/or itchy skin, soreness, redness and scaling around the mouth, and severe burning, crusting, or flaking of the skin."

Answered by AI

What is fluocinonide used to treat?

"Fluocinonide is a topical cream used to treat various skin conditions including psoriasis, eczema, and discomfort. The cream works by reducing inflammation and itchy, dry skin."

Answered by AI

Is fluocinonide a strong steroid?

"Fluocinonide is a medication used to reduce swelling, itching, and redness in conditions such as eczema and psoriasis. It is a strong corticosteroid."

Answered by AI

Clinical Trials for Fluocinonide

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Cognitive Remediation for Memory and Thinking Difficulties

18+
All Sexes
Farmington, CT
The goal of this clinical trial is to determine if a neuroscience-based computerized cognitive remediation ("brain training") program can treat neurocognitive dysfunction (i.e., memory or thinking difficulties) that emerges in some older adults following a viral infection. The main questions it aims to answer are: * Does computerized cognitive remediation improve cognitive performance and day-to-day functioning in older adults with postviral neurocognitive dysfunction? * Will treatment effects be maintained over time, leading to better long term cognitive outcomes? * Does the treatment lead to reductions in blood-based markers of inflammation as a potential mechanism of cognitive symptom improvement? * Can the treatment be optimized and refined based on feedback from participants to improve user (patient) experience? Researchers will compare the computerized cognitive remediation program to an active computer-based control condition (alternative computer activities) to see if the computerized cognitive remediation program works to treat postviral neurocognitive dysfunction. Participation takes approximately 43-48 hours over 7 months, with most activities (40-46 hours) completed within the first 7-8 weeks, including: * Initial intake visit: Eligibility confirmation (\~2-3 hours) * Computer activities: About 5 hours per week for \~6 weeks (total \~30 hours) completed on a computer tablet provided by the study and loaned to participants for use during the treatment phase * Weekly remote check-in meetings: \~30 minutes each during treatment * Blood draws: Two sessions (before and after treatment), \~20-30 minutes each * Three research visits: Pre-treatment, post-treatment, and 6-month follow-up (\~2-3 hours each, including assessments of cognitive, emotional, and daily functioning)
Waitlist Available
Has No Placebo
UConn HealthCutter Lindbergh, Ph.D.
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Freeze-dried Grape Powder for Healthy Aging

50 - 75
All Sexes
Storrs, CT
The purpose of this study is to investigate the effects of consuming grape powder on immune profiles in healthy middle- and older-aged individuals. Specifically, the investigators are interested in evaluating the potential effects of grapes in influencing markers of immune function, inflammation, and metabolism that are known to change with aging. Grapes contain several nutrients and antioxidant polyphenols such as resveratrol, quercetin, vitamin K and fiber, which are known to promote heart and immune health. However, the effects of grapes on altering immune profiles within the context of aging is not well understood. Therefore, this study will explore how daily grape consumption impacts certain markers of immunity in healthy middle- and older-aged adults. The main study procedures include consumption of a freeze-dried grape powder and control powder (which tastes the same but has none of the grape compounds that are being studied) mixed with water as a beverage on a daily basis for 4 weeks each. The investigators will additionally ask that participants avoid eating grapes and certain other antioxidant/grape-related foods and beverages throughout the 13-week study. Participants will additionally be asked to complete surveys about their diet, physical activity, and medical history, as well as provide blood samples and body weight measures throughout the course of the study. Participation in the study is expected to last about 6.25 hours over the course of 13 weeks and will include 7 visits.
Recruiting
Paid Trial
Department of Nutritional Sciences
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Orticumab for Heart Attack

18+
All Sexes
Los Angeles, CA
The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardial infarction who have elevated coronary inflammation based on CCTA. The main question it aims to answer is: Clinical effects of orticumab treatment on inflammation of the coronary artery parameters measured with CCTA Researchers will compare the effects with placebo group after 6 months of treatment Participants will Keep the planned study visit appointments Provide complete information about medical and medical history Speak to the study doctor before changing any of non-study treatments, including starting new medications, receiving any vaccinations, or setting out to join any other clinical studies
Phase 2
Recruiting
Abcentra Investigational Site (+6 Sites)Abcentra
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Biophoton Therapy for Stem Cell Proliferation

18 - 70
All Sexes
Tampa, FL
Study Objective The purpose of this clinical study is to evaluate if biophoton therapy, delivered by Tesla BioHealing® Biophoton Generators (Biophotonizer), can increase self-grown stem cells naturally. Study Design This is a randomized, double-blinded, placebo-controlled intervention clinical study to assess the effectiveness of biophoton therapy in impacting stem cells. Approximately 46 volunteers who want to increase self-grown stem cells will participate in the study. Study Randomization The biostatistician will prepare a randomization schedule including a serial of subject numbers. A subject number will be randomly assigned to each study participant, which will assign them to either the control group or the treatment group. Other than the Informed Consent Form (ICF), all study information will be recorded by using the subject number. The Principal Investigator, study physicians, study nurse, data-entry specialists, and biostatisticians, as well as the participants, will be blinded about who received which product during the first two weeks of study participation.
Recruiting
Online Trial
Tesla MedBed at Tampa-FL (+1 Sites)James Z Liu, MD, PhD
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Physical Activity for Delayed Onset Muscle Soreness

18 - 35
All Sexes
Toronto, Canada
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS). DOMS is characterized by muscle pain and tenderness that typically resolves within a week. While the precise cause of DOMS is unknown, there is growing evidence implicating damage to the connective tissue that surrounds our muscle fibers and is related to a small amount of inflammation. This inflammation is a normal part of our body's ability to recovery from injuries and may be visualized through the use of ultrasound technology. A variety of recovery techniques have been proposed that may help with the recovery of DOMS such as massage and electrical muscle stimulation, but these are not always accessible. Therefore, we are interested in investigating whether the number of daily steps can affect how you experience DOMS.
Waitlist Available
Has No Placebo
Goldring Center for High Performance Sport
Have you considered Fluocinonide clinical trials? We made a collection of clinical trials featuring Fluocinonide, we think they might fit your search criteria.Go to Trials
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Mediterranean Diet for Inflammation Post-Colonoscopy

18+
All Sexes
San Diego, CA
This study aims to investigate the impact of various healthy diets, specifically a modified plant-based Mediterranean diet, on the gut microbiome and overall well-being post-colonoscopy. The investigators hypothesize that certain diets can positively influence gut bacteria, reducing inflammation and enhancing metabolic signals. To explore this, they will utilize metagenomic testing on stool samples to analyze the DNA of gut microorganisms. Additionally, they will conduct immune profiling on serum samples and perform metabolomic analysis to comprehensively evaluate the diet-induced changes in immune response and metabolic pathways. This multi-faceted approach will help them understand how dietary changes affect the composition and function of the gut microbiome, immune function, and overall metabolism.
Recruiting
Has No Placebo
University of California, San Diego Altman Clinical and Translational Research Institute
Have you considered Fluocinonide clinical trials? We made a collection of clinical trials featuring Fluocinonide, we think they might fit your search criteria.Go to Trials
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